ATI RN
Proctored Pharmacology ATI
1. Hydrochlorothiazide is classified as a
- A. Anti-inflammatory
- B. Antiarrhythmic
- C. Diuretic
- D. Antifungal
Correct answer: C
Rationale: Hydrochlorothiazide is classified as a diuretic. Diuretics are medications that help the body get rid of excess salt and water by increasing urine production, reducing fluid retention, and lowering blood pressure. Option A, Anti-inflammatory, is incorrect because hydrochlorothiazide does not primarily reduce inflammation. Option B, Antiarrhythmic, is incorrect because hydrochlorothiazide is not used to correct heart rhythm irregularities. Option D, Antifungal, is incorrect because hydrochlorothiazide is not used to treat fungal infections.
2. A healthcare professional is preparing to administer Pamidronate to a client who has bone pain related to cancer. Which of the following precautions should the healthcare professional take when administering pamidronate?
- A. Inspect the IV site for redness and irritation when changing the intravenous patch.
- B. Assess the IV site for thrombophlebitis frequently during administration.
- C. Instruct the client to sit upright or stand for 30 min following intravenous administration.
- D. Watch for manifestations of anaphylaxis for 20 min after intramuscular administration.
Correct answer: B
Rationale: Pamidronate is administered through intravenous (IV) infusion. As this medication can be irritating to veins, the healthcare professional should carefully assess the IV site for thrombophlebitis during administration to prevent potential complications. Choice A is incorrect as Pamidronate is not administered via intradermal patch. Choice C is incorrect as it does not relate to the administration of Pamidronate. Choice D is incorrect as Pamidronate is not administered intramuscularly.
3. When educating a client prescribed Rifampin, which instruction should the nurse provide?
- A. Expect orange discoloration of urine.
- B. Take the medication with food.
- C. Increase your intake of dairy products.
- D. Discontinue the medication if you experience itching.
Correct answer: A
Rationale: The correct instruction for a client prescribed Rifampin is to expect orange discoloration of urine. Rifampin is known to cause harmless discoloration of bodily fluids, including urine, which is a common side effect of this medication. It is important for the nurse to educate the client about this expected side effect to prevent unnecessary concern or discontinuation of the medication. Choices B, C, and D are incorrect because Rifampin does not require specific dietary considerations like taking it with food or increasing dairy intake. Furthermore, itching is not a common side effect that would necessitate immediate discontinuation of Rifampin.
4. When a client is receiving treatment with methotrexate, which supplement should the nurse instruct the client to take?
- A. Folic acid
- B. Vitamin D
- C. Calcium
- D. Iron
Correct answer: A
Rationale: Folic acid supplementation is crucial for clients undergoing methotrexate treatment because methotrexate functions as a folic acid antagonist. By supplementing with folic acid, the risk of methotrexate toxicity can be minimized, improving the treatment's effectiveness and safety. Vitamin D, calcium, and iron are not specifically recommended in conjunction with methotrexate therapy and may not provide the same protective benefits as folic acid.
5. Potassium-sparing diuretics primarily affect which part of the kidney?
- A. Proximal convoluted tubule
- B. Loop of Henle
- C. Collecting duct
- D. Distal convoluted tubule
Correct answer: D
Rationale: Potassium-sparing diuretics exert their primary effects on the distal convoluted tubule in the kidney. By acting on this specific part of the nephron, these diuretics promote sodium excretion while sparing potassium, thus helping to maintain potassium levels in the body. This mechanism differs from other diuretics that may cause potassium loss as a side effect. Understanding the site of action of potassium-sparing diuretics is crucial in clinical practice for managing conditions like hypertension and edema where diuresis is necessary without the risk of hypokalemia.
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