ATI RN
Pathophysiology Practice Exam
1. A person is given an attenuated antigen as a vaccine. When the person asks what was given in the vaccine, how should the nurse respond? The antigen is:
- A. Alive, but less infectious
- B. Mutated, but highly infectious
- C. Normal, but not infectious
- D. Inactive, but infectious
Correct answer: A
Rationale: An attenuated antigen used in a vaccine is alive but less infectious, aiming to stimulate an immune response. Choice B is incorrect because an attenuated antigen is not highly infectious. Choice C is incorrect as the antigen is intentionally altered to be less infectious. Choice D is incorrect as an attenuated antigen is not infectious.
2. A client with a history of smoking presents with a chronic cough and shortness of breath. The nurse should suspect which condition?
- A. Pulmonary fibrosis
- B. Chronic obstructive pulmonary disease (COPD)
- C. Lung cancer
- D. Pulmonary edema
Correct answer: B
Rationale: The correct answer is B: Chronic obstructive pulmonary disease (COPD). COPD is often associated with a chronic cough and shortness of breath, especially in individuals with a history of smoking. Pulmonary fibrosis (choice A) typically presents with progressive dyspnea and dry cough. Lung cancer (choice C) may present with a chronic cough, shortness of breath, and other symptoms like weight loss and hemoptysis. Pulmonary edema (choice D) presents with symptoms such as acute shortness of breath, orthopnea, and pink, frothy sputum.
3. Which of the following eye disorders manifests with red eye, pain, and visual acuity changes?
- A. Bacterial conjunctivitis
- B. Acute closed-angle glaucoma
- C. Chronic open-angle glaucoma
- D. Blepharitis
Correct answer: B
Rationale: Acute closed-angle glaucoma presents with symptoms such as a red eye, severe pain, and rapid visual acuity changes due to increased intraocular pressure. This condition is considered an ophthalmologic emergency. Bacterial conjunctivitis typically presents with redness, discharge, and irritation but is not associated with severe pain or visual changes. Chronic open-angle glaucoma is usually asymptomatic until advanced stages and does not typically present with acute pain. Blepharitis involves inflammation of the eyelid margins and is characterized by redness and irritation, but it does not cause severe pain or acute visual changes.
4. A child with a serious fungal infection is receiving amphotericin B parenterally. Which of the following minerals will the patient most likely be required to receive?
- A. Chloride
- B. Magnesium
- C. Glucose
- D. Sodium
Correct answer: B
Rationale: When a patient is receiving amphotericin B, which is known to cause renal toxicity, they are most likely to require magnesium supplementation. Amphotericin B can lead to renal loss of magnesium, potassium, and calcium. Magnesium is an essential mineral that plays a vital role in various physiological functions, and its levels need to be monitored and supplemented when necessary. Chloride, glucose, and sodium are not typically supplemented in the context of amphotericin B therapy for a serious fungal infection.
5. What causes type I diabetes?
- A. Overproduction of insulin from the beta cells of the pancreas
- B. Destruction of the beta cells within the pancreas, resulting in an inability to produce insulin
- C. Loss of insulin receptors on the target cells, resulting in insulin resistance
- D. A pituitary tumor in the brain, resulting in increased antidiuretic hormone production
Correct answer: B
Rationale: Type I diabetes is caused by the destruction of the beta cells in the pancreas, leading to an inability to produce insulin. This results in a lack of insulin, leading to hyperglycemia. Choice A is incorrect as type I diabetes is characterized by a deficiency of insulin production, not overproduction. Choice C describes the pathophysiology of type 2 diabetes, where insulin receptors become less responsive to insulin. Choice D is unrelated to type I diabetes as it describes a pituitary tumor causing increased antidiuretic hormone production.
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