ATI RN
Oncology Test Bank
1. What is a characteristic of normal cells?
- A. They have no functions
- B. They have a larger nucleus
- C. They undergo apoptosis
- D. They have a dark-colored nucleus
Correct answer: C
Rationale: The correct answer is that normal cells undergo apoptosis, which is a programmed cell death process essential for maintaining tissue homeostasis. Choice A is incorrect as normal cells do have specific functions. Choice B is incorrect as the size of the nucleus may vary but is not a defining characteristic of normal cells. Choice D is incorrect as the color of the nucleus is not a standard characteristic of normal cells.
2. A client hospitalized for chemotherapy has a hemoglobin of 6.1 mg/dL (61 mmol/L). The client is symptomatic but refuses blood transfusions. What medication does the nurse prepare to administer?
- A. Epoetin alfa.
- B. Filgrastim.
- C. Mesna.
- D. Dexrazoxane.
Correct answer: A
Rationale: Epoetin alfa stimulates the production of red blood cells, which is important for a client who refuses blood transfusions.
3. A client is diagnosed as having a positive reaction to the Mantoux test. Which of the following is the most appropriate nursing action?
- A. Isolate the client in a private room.
- B. Administer isoniazid (INH) as prescribed.
- C. Schedule the client for a chest x-ray.
- D. Begin a 9-month course of medication therapy.
Correct answer: C
Rationale: The correct answer is to schedule the client for a chest x-ray. A positive Mantoux test indicates exposure to TB, but it does not confirm active disease. A chest x-ray is necessary to assess the presence of active TB disease. Isolating the client in a private room (Choice A) is not necessary based solely on a positive Mantoux test result. Administering isoniazid (INH) (Choice B) or beginning a 9-month course of medication therapy (Choice D) is premature without confirming active TB through a chest x-ray.
4. A patient with Hodgkin lymphoma is receiving chemotherapy. Which side effect is the nurse most concerned about?
- A. Nausea and vomiting
- B. Alopecia
- C. Fatigue
- D. Peripheral neuropathy
Correct answer: D
Rationale: The correct answer is D, Peripheral neuropathy. This can be a serious and dose-limiting side effect of chemotherapy for Hodgkin lymphoma. Peripheral neuropathy can cause tingling, numbness, and pain in the hands and feet due to nerve damage. While nausea and vomiting, alopecia, and fatigue are common side effects of chemotherapy, they are not typically as concerning or dose-limiting as peripheral neuropathy in the context of Hodgkin lymphoma treatment.
5. An oncology nurse educator is providing health education to a patient who has been diagnosed with skin cancer. The patient’s wife has asked about the differences between normal cells and cancer cells. What characteristic of a cancer cell should the educator cite?
- A. Malignant cells contain more fibronectin than normal body cells.
- B. Malignant cells contain proteins called tumor-specific antigens.
- C. Chromosomes contained in cancer cells are more durable and stable than those of normal cells.
- D. The nuclei of cancer cells are unusually large, but regularly shaped.
Correct answer: B
Rationale: Malignant (cancer) cells often express tumor-specific antigens (TSAs), which are proteins or markers on the surface of cancer cells that are not found on normal cells. These antigens are produced due to genetic mutations in cancer cells and can sometimes be used to help the immune system recognize and attack cancerous cells. Tumor-specific antigens play a key role in cancer diagnosis, monitoring, and targeted therapies.
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