ATI RN
ATI Pharmacology
1. When teaching a client with a new prescription for Simvastatin, which instruction should be included?
- A. Take this medication with food.
- B. Avoid drinking grapefruit juice.
- C. Take this medication in the morning.
- D. Increase your intake of potassium-rich foods.
Correct answer: B
Rationale: The correct instruction for a client with a new prescription for Simvastatin is to avoid drinking grapefruit juice. Grapefruit juice can inhibit the metabolism of Simvastatin, leading to increased blood levels of the drug and a higher risk of adverse effects such as muscle pain and liver damage. It is important to educate the client about this potential interaction to ensure the safe and effective use of the medication. Choices A, C, and D are incorrect because taking Simvastatin with food or in the morning and increasing potassium-rich foods intake are not specifically related to the safe use of Simvastatin. Avoiding grapefruit juice is crucial to prevent drug interactions.
2. A healthcare professional is preparing to administer vancomycin 1 g by intermittent IV bolus. Available is vancomycin 1 g in 100 mL of dextrose 5% in water (D5W) to infuse over 45 min. The drop factor of the manual IV tubing is 10 gtt/mL. How many gtt/min should the healthcare professional adjust the manual IV infusion to deliver?
- A. 22 gtt/min
- B. 24 gtt/min
- C. 20 gtt/min
- D. 18 gtt/min
Correct answer: A
Rationale: To calculate the flow rate, use the formula: (Volume in mL x Drop factor) / Time in minutes = Flow rate in gtt/min. In this case, (100 mL x 10 gtt/mL) / 45 min = 22 gtt/min. Thus, the healthcare professional should adjust the manual IV infusion to deliver 22 gtt/min. Choice B, 24 gtt/min, is incorrect because it miscalculates the flow rate. Choices C and D, 20 gtt/min and 18 gtt/min, are also incorrect as they do not accurately calculate the flow rate based on the given information.
3. A client is starting a new prescription for levothyroxine. Which of the following instructions should the nurse include?
- A. Take the medication at bedtime.
- B. Take the medication with food.
- C. Take the medication first thing in the morning on an empty stomach.
- D. Take the medication with a full glass of milk.
Correct answer: C
Rationale: The correct instruction for taking levothyroxine is to take the medication first thing in the morning on an empty stomach. This timing is important for optimal absorption of the medication. Taking levothyroxine with food or at bedtime can interfere with its absorption. Milk and other foods, as well as certain medications, can reduce the effectiveness of levothyroxine by interfering with its absorption, so it should be taken separately from these items. Therefore, the correct choice is to take the medication first thing in the morning on an empty stomach.
4. A client has a prescription for hydrochlorothiazide to treat hypertension. The nurse should monitor the client for which of the following adverse effects?
- A. Hypokalemia
- B. Hypertension
- C. Hyperglycemia
- D. Hypercalcemia
Correct answer: A
Rationale: Hydrochlorothiazide is a diuretic that can cause potassium loss, leading to hypokalemia. Monitoring potassium levels is crucial to prevent potential adverse effects such as cardiac arrhythmias and muscle weakness.
5. A client is being taught about Terbutaline. Which statement by the client indicates understanding of the teaching?
- A. This medication will stop my contractions.
- B. This medication will prevent vaginal bleeding.
- C. This medication will promote blood flow to my baby.
- D. This medication will increase my prostaglandin production.
Correct answer: A
Rationale: The correct answer is A. Terbutaline works by blocking beta2-adrenergic receptors, leading to uterine smooth muscle relaxation and stopping contractions. Therefore, the client demonstrating understanding by recognizing that the medication will stop contractions is the most accurate response. Choices B, C, and D are incorrect because Terbutaline is primarily used to inhibit contractions in preterm labor, not prevent vaginal bleeding, promote blood flow to the baby, or increase prostaglandin production.
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