a nurse is caring for a client who receives rituximab to treat non hodgkins leukemia and who asks the nurse how rituximab works which of the following
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Nursing Elites

ATI RN

ATI Proctored Pharmacology Test

1. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?

Correct answer: C

Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.

2. A client has a new prescription for Sucralfate to treat a duodenal ulcer. Which of the following instructions should be included?

Correct answer: C

Rationale: The correct instruction for taking Sucralfate is to take it 1 hour before meals. This timing allows the medication to coat the stomach lining, providing a protective barrier against stomach acid, which aids in healing the duodenal ulcer. Option A is incorrect as it contradicts the correct timing for taking Sucralfate. Option B is not necessary as it does not pertain to how the medication should be taken in relation to meals. Option D is incorrect as chewing the tablet before swallowing is not the correct administration method for Sucralfate.

3. A client has a new prescription for Clonidine. Which of the following instructions should the nurse include?

Correct answer: A

Rationale: The correct answer is to expect to feel drowsy. Clonidine is known to cause drowsiness, especially at the beginning of treatment. It is important for clients to be cautious with activities that require alertness until they understand how the medication affects them. Choice B is incorrect as there is no specific need to increase high-potassium foods with Clonidine. Choice C is incorrect as grapefruit juice can interact with many medications but is not a typical instruction for Clonidine. Choice D is incorrect as there is no specific indication to avoid foods high in fat with Clonidine.

4. A client has a prescription for Prednisone for the treatment of Rheumatoid Arthritis. Which of the following statements by the client indicates an understanding of the teaching?

Correct answer: A

Rationale: The correct answer is A. Prednisone can cause hypokalemia, leading to low potassium levels. Increasing the intake of potassium-rich foods helps prevent this imbalance. Choices B, C, and D are incorrect because taking Prednisone with food, decreasing calcium-rich foods, or avoiding grapefruit are not specifically related to addressing the side effect of hypokalemia associated with Prednisone.

5. When does regular insulin typically peak?

Correct answer: D

Rationale: Regular insulin usually peaks around 1 to 5 hours after administration. This peak time frame is important to consider when managing blood glucose levels and timing meals to coincide with insulin activity. Choice A, '30 minutes to 2 ½ hours,' is incorrect because regular insulin typically peaks later. Choice B, '1 to 3 hours,' is not the most accurate as the peak for regular insulin can extend beyond 3 hours. Choice C, '6 to 14 hours,' is incorrect as this timeframe is more indicative of long-acting insulins, not regular insulin.

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