ATI RN
ATI Proctored Pharmacology Test
1. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?
- A. Blocks hormone receptors
- B. Increases immune response
- C. Binds with specific antigens on tumor cells
- D. Stops DNA replication during cell division
Correct answer: C
Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.
2. A client has a new prescription for Etravirine, an NNRTI. Which of the following statements should the nurse include in teaching the client?
- A. Take this medication with food.
- B. Take this medication on an empty stomach.
- C. Take this medication at the same time every day.
- D. Take this medication at bedtime to prevent drowsiness.
Correct answer: C
Rationale: The correct statement the nurse should include in teaching the client is to take Etravirine at the same time every day. This ensures consistent blood levels and effectiveness of the medication. Consistent timing is essential to achieve optimal therapeutic effects and avoid missing doses. Choices A and B are incorrect because Etravirine should not necessarily be taken with or without food; it is more important to take it consistently. Choice D is incorrect as there is no need to take Etravirine at bedtime to prevent drowsiness.
3. A client asks a nurse about Feverfew. Which response should the nurse provide?
- A. It is used to treat skin infections.
- B. It can decrease the frequency of migraine headaches.
- C. It can lessen the nasal congestion in the common cold.
- D. It can relieve nausea of morning sickness during pregnancy.
Correct answer: B
Rationale: The correct response is B: 'It can decrease the frequency of migraine headaches.' Feverfew is known for reducing the frequency of migraine headaches, but it has not been proven to relieve an existing migraine headache. Choices A, C, and D are incorrect because Feverfew is not used to treat skin infections, lessen nasal congestion in the common cold, or relieve nausea of morning sickness during pregnancy.
4. A client is prescribed gentamicin for an infection. Which finding indicates a potential adverse reaction to the medication?
- A. Blood pressure 160/90 mm Hg
- B. Presence of red blood cells in the urine
- C. Urine output of 35 mL/hr
- D. Respiratory rate of 22/min
Correct answer: B
Rationale: The presence of red blood cells in the urine is a significant finding that can indicate nephrotoxicity, a potential adverse effect of gentamicin. Nephrotoxicity can lead to kidney damage, and monitoring for this adverse reaction is crucial during gentamicin therapy. Elevated blood pressure (Choice A) is not typically associated with gentamicin adverse reactions. Decreased urine output (Choice C) may suggest kidney impairment but is not as specific as the presence of red blood cells in the urine. Respiratory rate (Choice D) is not directly related to potential adverse reactions to gentamicin.
5. A healthcare professional is providing discharge instructions to a client who has a new prescription for Furosemide. Which of the following instructions should the healthcare professional include?
- A. Take the medication with breakfast.
- B. Increase intake of foods high in potassium.
- C. Avoid prolonged sun exposure.
- D. Limit sodium intake.
Correct answer: B
Rationale: The correct answer is B: 'Increase intake of foods high in potassium.' Furosemide, a loop diuretic, can cause potassium depletion. The healthcare professional should instruct the client to increase the intake of foods high in potassium to prevent hypokalemia, a potential side effect of Furosemide therapy. Choice A is incorrect as Furosemide is usually recommended to be taken in the morning to prevent nocturia. Choice C is unrelated to the side effects of Furosemide. Choice D, while important for overall health, is not directly related to the side effects of Furosemide.
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