a nurse is caring for a client who receives rituximab to treat non hodgkins leukemia and who asks the nurse how rituximab works which of the following
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Nursing Elites

ATI RN

ATI Proctored Pharmacology Test

1. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?

Correct answer: C

Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.

2. A client is receiving chemotherapy and has a prescription for ondansetron IV for nausea and vomiting. The nurse should monitor the client for which of the following adverse effects?

Correct answer: C

Rationale: The correct answer is C: Tremors. Ondansetron can cause tremors as an adverse effect. Monitoring for tremors is essential as it can indicate a potential adverse reaction to the medication. Hypotension (choice A) and bradycardia (choice B) are not commonly associated with ondansetron. Urinary retention (choice D) is also not a typical adverse effect of ondansetron, making choices A, B, and D incorrect in this scenario.

3. Which of the following is the antidote for Heparin toxicity?

Correct answer: A

Rationale: Protamine is the specific antidote for Heparin toxicity. Heparin is an anticoagulant medication, and if an overdose occurs or if there is excessive bleeding due to Heparin use, protamine, a positively charged molecule, can neutralize the anticoagulant effects of Heparin by forming a complex with it. This binding prevents Heparin from further inhibiting coagulation factors and helps in reversing its effects.

4. When teaching a client how to use nitroglycerin transdermal ointment for angina, which instruction should the nurse include?

Correct answer: A

Rationale: The correct instruction is to remove the prior dose before applying a new dose. This helps prevent toxicity by ensuring the client does not inadvertently apply an excessive amount of nitroglycerin.

5. When providing discharge instructions to a client with a new prescription for Levofloxacin, which of the following instructions should the nurse include?

Correct answer: B

Rationale: The correct answer is to instruct the client to avoid taking Levofloxacin with dairy products. This is because calcium in dairy products can interfere with the absorption of the medication. Patients should be advised to take Levofloxacin either 1 hour before or 2 hours after consuming dairy products to ensure optimal effectiveness. Choice A is incorrect because Levofloxacin can be taken with or without food. Choice C is incorrect as the timing of Levofloxacin administration is not specified as at bedtime. Choice D is also incorrect as there is no need to increase intake of potassium-rich foods specifically for Levofloxacin administration.

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