ATI RN
ATI Proctored Pharmacology Test
1. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?
- A. Blocks hormone receptors
- B. Increases immune response
- C. Binds with specific antigens on tumor cells
- D. Stops DNA replication during cell division
Correct answer: C
Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.
2. A client has a new prescription for lisinopril. Which of the following findings should the nurse monitor as an adverse effect of this medication?
- A. Cough
- B. Hyperglycemia
- C. Headache
- D. Dry mouth
Correct answer: A
Rationale: A common adverse effect of lisinopril is a persistent dry cough. Lisinopril is an ACE inhibitor that can cause irritation in the respiratory tract, leading to a cough. Monitoring for a persistent cough is essential as it may indicate a serious adverse effect that requires medical attention. Hyperglycemia (Choice B) is not a common adverse effect of lisinopril. Headache (Choice C) and dry mouth (Choice D) are not typically associated with lisinopril use. Therefore, the correct answer is A: Cough.
3. A client is receiving IV Dopamine for the treatment of shock. Which of the following findings indicates that the medication is effective?
- A. Increased heart rate
- B. Decreased blood pressure
- C. Increased urine output
- D. Decreased respiratory rate
Correct answer: C
Rationale: Dopamine is a medication used in shock to increase cardiac output and improve renal perfusion. An increase in urine output indicates that the medication is effective as it shows improved renal perfusion and kidney function, which are essential for managing shock effectively. Choices A, B, and D are incorrect as an increased heart rate, decreased blood pressure, and decreased respiratory rate are not direct indicators of the effectiveness of IV Dopamine in treating shock.
4. A healthcare professional is reviewing laboratory results for a client who is receiving heparin via continuous IV infusion. Which of the following results indicates that the heparin infusion should be increased?
- A. aPTT of 90 seconds
- B. Platelet count of 150,000/mm³
- C. INR of 1.0
- D. Hgb of 15 g/dL
Correct answer: A
Rationale: An aPTT of 90 seconds is above the therapeutic range for heparin, which typically falls between 60-80 seconds. This indicates that the current heparin dose is too high, and the infusion rate should be decreased to avoid excessive anticoagulation and the risk of bleeding. Monitoring aPTT is crucial in adjusting heparin therapy to maintain it within the therapeutic range.
5. A client is receiving Morphine IV for pain management. Which of the following actions should the nurse take?
- A. Monitor the client's respiratory rate every 15 minutes.
- B. Monitor the client's blood pressure every 30 minutes.
- C. Monitor the client's oxygen saturation every hour.
- D. Monitor the client's heart rate every 5 minutes.
Correct answer: A
Rationale: The correct action for the nurse is to monitor the client's respiratory rate every 15 minutes while on Morphine IV to promptly detect respiratory depression, a critical adverse effect associated with this medication. Respiratory depression is a common side effect of opioid medications like Morphine and can be life-threatening. Monitoring the respiratory rate frequently enables the nurse to identify early signs of respiratory compromise and intervene promptly. Monitoring other vital signs like blood pressure, oxygen saturation, or heart rate is important but not as crucial as monitoring respiratory rate when a client is on Morphine IV.
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