a nurse is caring for a client who receives rituximab to treat non hodgkins leukemia and who asks the nurse how rituximab works which of the following
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Nursing Elites

ATI RN

ATI Proctored Pharmacology Test

1. A client asks the nurse how Rituximab works, which the client is receiving to treat Non-Hodgkin's Leukemia. Which of the following should the nurse include?

Correct answer: C

Rationale: Rituximab is a monoclonal antibody that binds with specific antigens on B-lymphocytes, leading to the destruction of cancer cells. In the context of Non-Hodgkin's Leukemia, Rituximab targets and destroys cancerous B-lymphocytes, which helps in treating the disease. Choices A, B, and D are incorrect. Rituximab does not block hormone receptors, increase immune response, or stop DNA replication during cell division. The primary mode of action of Rituximab is its binding with specific antigens on tumor cells, specifically B-lymphocytes, to elicit an immune response against cancerous cells.

2. A healthcare professional is preparing to administer Diltiazem IV to a client who has atrial fibrillation. Which of the following findings should the healthcare professional report immediately?

Correct answer: A

Rationale: The correct answer is bradycardia. Diltiazem, a calcium channel blocker, can lead to bradycardia as a side effect. Bradycardia should be reported immediately because it can result in serious cardiac complications, especially in a client with atrial fibrillation. Hypertension, shortness of breath, and tachycardia are not typically associated with Diltiazem administration and would not be immediate concerns in this scenario.

3. A client has a new prescription for Lovastatin. Which of the following instructions should the nurse include?

Correct answer: C

Rationale: The correct instruction for taking Lovastatin is to take it at bedtime. Cholesterol production in the liver is highest at night, so taking Lovastatin at bedtime aligns with the body's natural rhythm and maximizes its effectiveness.

4. Which part of the body requires a continuous supply of oxygen and vital nutrients to support life and death?

Correct answer: C

Rationale: The brain requires a continuous supply of oxygen and vital nutrients to support life and prevent death. Oxygen and nutrients are essential for brain function, and any interruption in the supply can lead to serious consequences, including brain damage or death. Therefore, ensuring a constant flow of oxygen and nutrients to the brain is vital for survival and overall health.

5. What instruction should the healthcare provider include to minimize an adverse effect of Clomipramine for OCD in an adolescent client?

Correct answer: A

Rationale: The correct answer is A: 'Wear sunglasses when outdoors.' To minimize the anticholinergic effect of Clomipramine, the client should wear sunglasses when outdoors to reduce photophobia. This adverse effect is common with tricyclic antidepressant (TCA) use. Choices B, C, and D are incorrect. Checking temperature daily, timing of medication intake, or adding extra calories to the diet are not directly related to minimizing adverse effects of Clomipramine.

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