Nursing Elites

1. A client is starting therapy with topotecan. Which of the following findings should the nurse instruct the client to report?

• A. Hair loss
• B. Fatigue
• C. Sore throat
• D. Red urine

Correct answer: C

Rationale: The nurse should instruct the client to report a sore throat because it can indicate an infection due to the immunosuppressive effects of topotecan. Monitoring for signs of infection is crucial to prevent complications during therapy. Choices A, B, and D are less critical findings compared to a sore throat. Hair loss is a common side effect of chemotherapy, fatigue is expected with cancer treatment, and red urine is a known harmless effect of topotecan.

2. A client has a new prescription for Atorvastatin. Which of the following instructions should be included?

• A. Take this medication with food.
• B. Avoid drinking grapefruit juice.
• C. Take this medication in the morning.
• D. Increase your intake of potassium-rich foods.

Correct answer: B

Rationale: The correct answer is to avoid drinking grapefruit juice when taking Atorvastatin. Grapefruit juice can interfere with the metabolism of Atorvastatin, leading to increased blood levels of the medication, which can result in a higher risk of adverse effects, such as muscle pain and liver damage. It is important for the client to follow this instruction to ensure the safe and effective use of Atorvastatin. Choices A, C, and D are incorrect. While taking Atorvastatin with food may be recommended for some individuals to reduce stomach upset, it is not a crucial instruction. The timing of Atorvastatin administration can vary depending on individual needs and is not universally fixed to the morning. Increasing potassium-rich foods is not directly related to Atorvastatin use and is not a standard precautionary measure associated with this medication.

3. A client has a new prescription for Digoxin to treat heart failure. Which of the following findings should the nurse monitor as an adverse effect?

• A. Visual disturbances
• B. Dry cough
• C. Confusion
• D. Urinary retention

Correct answer: A

Rationale: Visual disturbances, such as blurred or yellow vision, can be an early sign of digoxin toxicity. Monitoring for visual changes is crucial to detect and prevent potential adverse effects of digoxin. Dry cough, confusion, and urinary retention are not commonly associated adverse effects of digoxin and are not typically monitored in relation to this medication.

4. A client is taking oral Oxycodone and Ibuprofen in recommended doses. The nurse should identify that an interaction between these two medications will cause which of the following findings?

• A. A decrease in serum levels of ibuprofen, possibly leading to a need for increased doses of this medication.
• B. A decrease in serum levels of oxycodone, possibly leading to a need for increased doses of this medication.
• C. An increase in the expected therapeutic effect of both medications.
• D. An increase in expected adverse effects for both medications.

Correct answer: C

Rationale: When Oxycodone, a narcotic analgesic, and Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), are taken together, they work synergistically to enhance the pain-relieving effects of both medications. These drugs act through different mechanisms, leading to a combined analgesic effect that is more effective than when used alone. Therefore, the interaction between Oxycodone and Ibuprofen results in an increase in the expected therapeutic effect of both medications.

5. A healthcare professional is caring for a group of clients receiving antimicrobial therapy. Which of the following clients should the professional plan to monitor for manifestations of antibiotic toxicity?

• A. An adolescent client with a sinus infection
• B. An older adult client with prostatitis
• C. A client who is postpartum with mastitis
• D. A middle-aged client with a urinary tract infection

Correct answer: B

Rationale: An older adult client with prostatitis who is receiving antibiotics should be monitored for toxicity due to age-related reductions in medication metabolism and excretion. Older adults are more susceptible to antibiotic toxicity, making them a high-risk group for adverse effects.

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