ATI RN
ATI Pharmacology Proctored
1. Which of the following conditions is not treated with epinephrine?
- A. Renal disease
- B. Asthma
- C. Hypotension
- D. Glaucoma
Correct answer: A
Rationale: Epinephrine is not used to treat renal disease. Epinephrine is commonly used to treat conditions like asthma, hypotension, and glaucoma, but it is not an appropriate treatment for renal disease. Renal disease requires specific management strategies that do not involve the use of epinephrine.
2. An older adult client has a new prescription for Digoxin and takes multiple other medications. The nurse should recognize that concurrent use of which of the following medications places the client at risk for Digoxin toxicity?
- A. Phenytoin
- B. Verapamil
- C. Warfarin
- D. Aluminum hydroxide
Correct answer: B
Rationale: Verapamil, a calcium-channel blocker, can increase digoxin levels, leading to toxicity. When given together, the digoxin dosage may need adjustment, and the nurse should closely monitor the client's digoxin levels to prevent toxicity symptoms such as nausea, vomiting, visual disturbances, and arrhythmias. The other choices, Phenytoin, Warfarin, and Aluminum hydroxide, do not significantly interact with Digoxin to cause toxicity. Phenytoin may reduce Digoxin levels, while Warfarin and Aluminum hydroxide have minimal interactions with Digoxin.
3. A client has a new prescription for Verapamil to control hypertension. Which of the following instructions should the nurse include?
- A. Increase the amount of dietary fiber in the diet.
- B. Drink grapefruit juice daily to increase vitamin C intake.
- C. Decrease the amount of calcium in the diet.
- D. Withhold food for 1 hr after taking the medication.
Correct answer: A
Rationale: Increasing dietary fiber intake is essential when taking Verapamil to prevent constipation, a common adverse effect of the medication. Dietary fiber can help maintain bowel regularity and alleviate constipation.
4. A client is taking Paroxetine to treat PTSD and reports teeth grinding at night. Which interventions should the nurse implement to manage Bruxism? (Select all that apply.)
- A. Concurrent administration of buspirone.
- B. Administration of a different SSRI.
- C. Use of a mouth guard.
- D. Changing to a different class of antidepressant medication.
Correct answer: A
Rationale: The correct interventions to manage Bruxism associated with Paroxetine use include A: Concurrent administration of buspirone. Buspirone can help alleviate the side effect of Bruxism. Additionally, C: Use of a mouth guard is recommended to prevent oral damage from teeth grinding. B: Administration of a different SSRI is not necessary since the issue is specific to Paroxetine. D: Changing to a different class of antidepressant medication may be considered in severe cases, but the initial step should be to add buspirone to address the Bruxism caused by Paroxetine.
5. A client receiving chemotherapy with Methotrexate asks why Leucovorin is being given. Which of the following responses should the nurse use?
- A. Leucovorin reduces the risk of a transfusion reaction from Methotrexate.
- B. Leucovorin increases platelet production and prevents bleeding.
- C. Leucovorin potentiates the cytotoxic effects of Methotrexate.
- D. Leucovorin protects healthy cells from Methotrexate's toxic effects.
Correct answer: D
Rationale: Leucovorin, a folic acid derivative and an antagonist to Methotrexate, is given within 12 hours of high doses of Methotrexate to protect healthy cells from the toxic effects of Methotrexate. It helps to reduce the bone marrow suppression and gastrointestinal side effects caused by Methotrexate, supporting the client's overall well-being during chemotherapy treatment. Choices A, B, and C are incorrect because Leucovorin does not reduce the risk of a transfusion reaction from Methotrexate, increase platelet production, prevent bleeding, or potentiate the cytotoxic effects of Methotrexate. Instead, Leucovorin works by rescuing healthy cells from the toxic effects of Methotrexate.
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