ATI RN
ATI Pharmacology Proctored
1. Potassium-sparing diuretics primarily affect which part of the kidney?
- A. Proximal convoluted tubule
- B. Loop of Henle
- C. Collecting duct
- D. Distal convoluted tubule
Correct answer: D
Rationale: Potassium-sparing diuretics exert their primary effects on the distal convoluted tubule in the kidney. By acting on this specific part of the nephron, these diuretics promote sodium excretion while sparing potassium, thus helping to maintain potassium levels in the body. This mechanism differs from other diuretics that may cause potassium loss as a side effect. Understanding the site of action of potassium-sparing diuretics is crucial in clinical practice for managing conditions like hypertension and edema where diuresis is necessary without the risk of hypokalemia.
2. A healthcare provider is reviewing a client's medication history and notes a new prescription for Enalapril. The healthcare provider should monitor the client for which of the following as an adverse effect of this medication?
- A. Bradycardia
- B. Hyperkalemia
- C. Hypoglycemia
- D. Hypocalcemia
Correct answer: B
Rationale: Enalapril, an ACE inhibitor, can cause hyperkalemia as an adverse effect due to decreased aldosterone levels, leading to potassium retention. Monitoring potassium levels is essential to prevent complications associated with hyperkalemia. Bradycardia (Choice A) is not a common adverse effect of Enalapril. Enalapril does not typically affect glucose levels, so hypoglycemia (Choice C) is not a common concern with this medication. Enalapril does not directly impact calcium levels, so hypocalcemia (Choice D) is not a typical adverse effect.
3. A client has a new prescription for Raltegravir. Which of the following statements should the nurse include in teaching the client?
- A. This medication prevents the virus from entering the cell.
- B. This medication prevents the virus from leaving the cell.
- C. This medication blocks the virus from attaching to the cell.
- D. This medication blocks the virus from replicating in the cell.
Correct answer: D
Rationale: The correct answer is D because Raltegravir works by blocking the integrase enzyme, preventing the virus from integrating its genetic material into the host cell's DNA. By inhibiting this process, viral replication within the host cell is halted. Choices A, B, and C are incorrect because Raltegravir's mechanism of action specifically targets viral replication within the cell, not virus entry, exit, or attachment to the cell.
4. Which of the following conditions are not treated with Barbiturates?
- A. Seizures
- B. Hypotension
- C. Insomnia
- D. Anxiety
Correct answer: B
Rationale: Hypotension is not treated with barbiturates. Barbiturates are primarily used for treating seizures, insomnia, and anxiety, but they are not indicated for the treatment of hypotension.
5. A client has a new prescription for Etravirine, an NNRTI. Which of the following statements should the nurse include in teaching the client?
- A. Take this medication with food.
- B. Take this medication on an empty stomach.
- C. Take this medication at the same time every day.
- D. Take this medication at bedtime to prevent drowsiness.
Correct answer: C
Rationale: The correct statement the nurse should include in teaching the client is to take Etravirine at the same time every day. This ensures consistent blood levels and effectiveness of the medication. Consistent timing is essential to achieve optimal therapeutic effects and avoid missing doses. Choices A and B are incorrect because Etravirine should not necessarily be taken with or without food; it is more important to take it consistently. Choice D is incorrect as there is no need to take Etravirine at bedtime to prevent drowsiness.
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