ATI RN
Oncology Test Bank
1. A patient with myelofibrosis is being treated with ruxolitinib. What should the nurse monitor to assess the effectiveness of this treatment?
- A. Blood pressure
- B. White blood cell count
- C. Hemoglobin and hematocrit
- D. Spleen size
Correct answer: C
Rationale: Monitoring hemoglobin and hematocrit is essential to assess the effectiveness of ruxolitinib in treating myelofibrosis. Ruxolitinib works by inhibiting JAK1 and JAK2, which are involved in the signaling pathways that regulate blood cell production. Therefore, monitoring hemoglobin and hematocrit levels can provide valuable information on how well the drug is managing the disease. Blood pressure, white blood cell count, and spleen size are not direct indicators of the treatment's effectiveness in myelofibrosis.
2. A nurse is creating a plan of care for an oncology patient and one of the identified nursing diagnoses is risk for infection related to myelosuppression. What intervention addresses the leading cause of infection-related death in oncology patients?
- A. Encourage several small meals daily.
- B. Provide skin care to maintain skin integrity.
- C. Assist the patient with hygiene, as needed.
- D. Assess the integrity of the patient’s oral mucosa regularly.
Correct answer: B
Rationale: In oncology patients, particularly those undergoing chemotherapy or radiation therapy, myelosuppression (the decrease in bone marrow activity that leads to reduced white blood cells, red blood cells, and platelets) increases the risk of infection. Maintaining skin integrity is crucial because the skin acts as the body's first line of defense against infections. If the skin becomes compromised, such as through radiation burns, rashes, or breakdowns, it provides a potential entry point for pathogens, increasing the risk of infection. Since infections in oncology patients can quickly become severe due to their weakened immune systems, maintaining skin integrity is a critical intervention to reduce infection risk, especially for patients who are immunosuppressed.
3. The nurse is instructing the 35 year old client to perform a testicular self-examination. The nurse tells the client:
- A. To examine the testicles while lying down
- B. That the best time for the examination is after a shower
- C. To gently feel the testicle with one finger to feel for a growth
- D. That testicular self-examination should be done at least every 6 months
Correct answer: B
Rationale: The best time to perform a testicular self-examination (TSE) is after a warm shower or bath. The heat from the water relaxes the scrotal skin, making it easier to feel any abnormalities, lumps, or changes in the testicles. This relaxation allows for a more thorough and accurate examination.
4. A nurse at a long-term care facility is amending the care plan of a resident who has just been diagnosed with essential thrombocythemia (ET). The nurse should anticipate the administration of what medication?
- A. Dalteparin
- B. Allopurinol
- C. Hydroxyurea
- D. Hydrochlorothiazide
Correct answer: C
Rationale: Hydroxyurea is effective in lowering the platelet count for patients with ET.
5. A client with breast cancer is receiving doxorubicin (Adriamycin). The nurse monitors the client closely for:
- A. Pulmonary fibrosis
- B. Cardiotoxicity
- C. Hepatotoxicity
- D. Nephrotoxicity
Correct answer: B
Rationale: Doxorubicin (Adriamycin) is an anthracycline chemotherapy agent commonly used to treat various cancers, including breast cancer. One of the significant side effects associated with doxorubicin is cardiotoxicity, which can lead to serious complications such as heart failure and arrhythmias. The risk of cardiotoxicity is dose-dependent, meaning that higher cumulative doses increase the likelihood of cardiac damage. Therefore, it is essential for nurses to monitor cardiac function closely through assessments such as echocardiograms or monitoring for signs and symptoms of heart failure, such as shortness of breath, fatigue, and edema.
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