ATI RN
ATI Pharmacology Proctored Exam
1. A healthcare professional is planning to administer IV Alteplase to a client who is demonstrating manifestations of a massive Pulmonary Embolism. Which of the following interventions should the healthcare professional plan to take?
- A. Administer IM Enoxaparin along with the Alteplase dose.
- B. Hold direct pressure on puncture sites for up to 30 min.
- C. Administer Aminocaproic acid IV prior to alteplase infusion.
- D. Prepare to administer Alteplase within 8 hr of manifestation onset.
Correct answer: B
Rationale: The correct intervention when administering IV Alteplase is to hold direct pressure on puncture sites for 10 to 30 minutes or until oozing of blood stops. This helps prevent bleeding complications associated with thrombolytic therapy. Administering IM Enoxaparin is not indicated with Alteplase, as it is an anticoagulant rather than a thrombolytic agent. Aminocaproic acid is not typically administered prior to alteplase infusion in the context of a massive Pulmonary Embolism. While timely administration of Alteplase is important, the specific timeframe within which it should be administered may vary based on the clinical situation, so a strict 8-hour window is not universally applicable.
2. A client has a new prescription for Propranolol. Which of the following findings should be identified as a contraindication to this medication?
- A. Asthma
- B. Diabetes mellitus
- C. Hypertension
- D. Glaucoma
Correct answer: A
Rationale: Corrected Rationale: Propranolol is a non-selective beta-blocker that can cause bronchoconstriction, making it contraindicated for clients with asthma. Asthma is a contraindication due to the potential for worsening bronchoconstriction and exacerbating respiratory symptoms. Choice B, diabetes mellitus, is not a contraindication for Propranolol. Choice C, hypertension, is actually an indication for Propranolol as it is commonly used to treat hypertension. Choice D, glaucoma, is not a contraindication for Propranolol use.
3. A client has a new prescription for Labetalol. Which of the following instructions should the nurse include?
- A. Take this medication at bedtime.
- B. Avoid sudden discontinuation of the medication.
- C. Increase your intake of sodium-rich foods.
- D. Avoid drinking grapefruit juice.
Correct answer: B
Rationale: The correct instruction for a client on Labetalol is to avoid sudden discontinuation of the medication. Labetalol is a beta-blocker that, if abruptly stopped, can lead to rebound hypertension and other cardiac issues. It is essential for patients to taper off this medication under medical supervision to prevent adverse effects.
4. Following a stroke, a client has been started on clopidogrel (Plavix). Why is this medication being administered?
- A. To prevent stroke in high-risk patients, such as those with prosthetic heart valves
- B. To decrease blood pressure
- C. To increase heart rate
- D. To provide antiplatelet activity in patients who cannot tolerate aspirin
Correct answer: D
Rationale: Clopidogrel (Plavix) is an antiplatelet medication that inhibits platelet aggregation, reducing the risk of blood clots. It is commonly used in patients who have had a stroke and cannot tolerate aspirin due to allergies or intolerances. Choosing clopidogrel in these cases helps prevent further clot formation and reduces the risk of recurrent strokes.
5. When starting therapy with raloxifene, a client should monitor for which of the following adverse effects?
- A. Leg cramps
- B. Hot flashes
- C. Urinary frequency
- D. Hair loss
Correct answer: B
Rationale: The correct answer is B: Hot flashes. When initiating therapy with raloxifene, clients should be advised to monitor for hot flashes as they are a common adverse effect associated with this medication. Hot flashes are a well-known side effect of raloxifene due to its action on estrogen receptors. Leg cramps (Choice A), urinary frequency (Choice C), and hair loss (Choice D) are not typically associated with raloxifene therapy. Therefore, monitoring for hot flashes is crucial to manage and address this common side effect appropriately.
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