HESI A2
HESI A2 Biology Practice Test
1. Which of the following is true of Glycolysis?
- A. It requires the absence of Oxygen
- B. It occurs in the presence of Oxygen
- C. It is the final step of fermentation
- D. It is the final step of anaerobic respiration
Correct answer: B
Rationale: Glycolysis is the first step in cellular respiration and can occur in both aerobic (presence of oxygen) and anaerobic (absence of oxygen) conditions. In aerobic respiration, glycolysis takes place in the presence of oxygen and continues with the Krebs cycle and the electron transport chain. So, glycolysis does not require the absence of oxygen but can occur in its presence as part of the overall process of aerobic respiration. Choice A is incorrect because glycolysis can occur in the presence of oxygen. Choice C is incorrect because glycolysis is not the final step of fermentation; it is the initial step. Choice D is incorrect because glycolysis is not the final step of anaerobic respiration; it is the first step, followed by further processes to complete anaerobic respiration.
2. During protein synthesis, what process creates a complementary strand of RNA from a DNA template?
- A. Transcription
- B. Translation
- C. Transformation
- D. Replication
Correct answer: A
Rationale: The correct answer is 'Transcription.' During protein synthesis, transcription is the process that creates a complementary RNA strand from a DNA template. This process involves the synthesis of mRNA using DNA as a template. Choice B, 'Translation,' is incorrect as it is the process where the genetic code carried by mRNA is decoded to produce a specific polypeptide chain. Choice C, 'Transformation,' is not related to the synthesis of RNA from a DNA template. Choice D, 'Replication,' is the process of copying DNA to produce an identical DNA molecule, not RNA.
3. Choose the two bases that have two carbon rings:
- A. Adenine
- B. Cytosine
- C. Thymine
- D. Guanine
Correct answer: A
Rationale: Adenine and guanine have two carbon rings and are known as purines. These bases are found in nucleic acids such as DNA and RNA. Adenine (option A) and guanine (option D) are the correct choices as they both have two carbon rings in their molecular structure. Cytosine (option B) and thymine (option C) have a single carbon ring each, making them incorrect choices for bases with two carbon rings.
4. Which organelle contains the genetic material of the cell?
- A. Golgi apparatus
- B. Ribosome
- C. Endoplasmic reticulum
- D. Nucleus
Correct answer: D
Rationale: The correct answer is 'D: Nucleus.' The nucleus is the organelle that contains the cell's genetic material, which is the DNA. The genetic material in the nucleus controls the cell's activities and plays a crucial role in inheritance. Choices A, B, and C are incorrect because the Golgi apparatus is involved in modifying, sorting, and packaging of proteins; ribosomes are involved in protein synthesis; and endoplasmic reticulum is involved in protein and lipid synthesis and transportation, but none of them contain the genetic material of the cell.
5. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
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