HESI A2
Biology HESI A2 Practice Test
1. Which of the following describes the situation where one allele takes a different form from another in a gene?
- A. phenotype
- B. heterozygous
- C. homolog
- D. homozygous
Correct answer: B
Rationale: Heterozygous is the term used to describe the genotype of an individual with two different alleles for a specific gene. In this case, one allele takes a different form from another, resulting in genetic diversity and variation in trait expression. The other choices are incorrect: 'phenotype' refers to the observable traits of an organism, 'homolog' typically refers to chromosomes that are similar in structure, and 'homozygous' describes the genotype where both alleles for a gene are the same.
2. Phenotype refers to the _ of an individual.
- A. Genetic makeup
- B. Actual physical appearance
- C. Recessive alleles
- D. None of the above
Correct answer: B
Rationale: Phenotype refers to the actual physical appearance and characteristics of an individual, which are determined by the interaction of both genetic makeup (genotype) and environmental factors. It includes visible traits such as height, eye color, and hair type. Choice A, genetic makeup, refers to the genotype, which is the genetic constitution of an organism. Choice C, recessive alleles, is a specific type of gene variant and does not encompass the entire concept of phenotype. Choice D, none of the above, is incorrect as phenotype does refer to the actual physical appearance of an individual.
3. How is the plasma membrane arranged?
- A. In a single layer made of proteins
- B. In a double layer made of proteins
- C. In a single layer of phospholipids
- D. In a double layer of phospholipids
Correct answer: D
Rationale: The plasma membrane is arranged in a double layer of phospholipids, known as a phospholipid bilayer. This structure consists of two layers of phospholipid molecules with hydrophilic heads facing the exterior and hydrophobic tails facing the interior, providing a semipermeable barrier for the cell. Choice A is incorrect because the plasma membrane is not made of a single layer of proteins. Choice B is incorrect as the double layer is composed of phospholipids, not proteins. Choice C is incorrect as the plasma membrane is not made of a single layer of phospholipids but rather a double layer.
4. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
5. During protein synthesis, what process creates a complementary strand of RNA from a DNA template?
- A. Transcription
- B. Translation
- C. Transformation
- D. Replication
Correct answer: A
Rationale: The correct answer is 'Transcription.' During protein synthesis, transcription is the process that creates a complementary RNA strand from a DNA template. This process involves the synthesis of mRNA using DNA as a template. Choice B, 'Translation,' is incorrect as it is the process where the genetic code carried by mRNA is decoded to produce a specific polypeptide chain. Choice C, 'Transformation,' is not related to the synthesis of RNA from a DNA template. Choice D, 'Replication,' is the process of copying DNA to produce an identical DNA molecule, not RNA.
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