HESI A2
HESI A2 Biology 2024
1. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.
2. What happens to glucose during glycolysis?
- A. Its energy is entirely lost.
- B. It splits into molecules of pyruvic acid.
- C. It is stored in NADH.
- D. It joins with molecules of citric acid.
Correct answer: B
Rationale: During glycolysis, glucose undergoes a series of enzymatic reactions in the cytoplasm of the cell, resulting in its breakdown into two molecules of pyruvic acid. This process also generates ATP and NADH as energy carriers. Choice A is incorrect because glucose is not entirely lost, but rather converted into other molecules. Choice C is incorrect because NADH is a product of glycolysis, not a storage form for glucose. Choice D is incorrect as glucose does not join with molecules of citric acid during glycolysis, but rather in subsequent stages of cellular respiration.
3. Dogs are part of a larger animal group, the Carnivora. What classification is this?
- A. Kingdom
- B. Class
- C. Order
- D. Genus
Correct answer: C
Rationale: The classification 'Carnivora' refers to an order in the taxonomic hierarchy. In the Linnaean classification system, the order comes below the class but above the family level. Therefore, Carnivora is a higher classification that includes dog species as well as other carnivorous mammals like cats, bears, and weasels. Option A (Kingdom) is too broad and refers to the highest taxonomic rank. Option B (Class) is a lower taxonomic rank than order. Option D (Genus) is a much more specific rank that comes below the family level in the Linnaean hierarchy.
4. In contrast with triglycerides, phospholipids are lacking one of which of the following components?
- A. Monosaccharide
- B. Glycerol
- C. Phosphates
- D. Fatty acid
Correct answer: B
Rationale: Phospholipids are structurally similar to triglycerides but lack one of the fatty acid chains that triglycerides possess. Triglycerides consist of three fatty acid chains attached to a glycerol molecule, while phospholipids have two fatty acid chains and a phosphate group attached to a glycerol backbone. Therefore, phospholipids are lacking the third fatty acid chain found in triglycerides. Choice A (Monosaccharide) is incorrect because neither triglycerides nor phospholipids contain monosaccharides in their structure. Choice C (Phosphates) is incorrect because phospholipids actually contain phosphates, unlike triglycerides. Choice D (Fatty acid) is incorrect as both triglycerides and phospholipids contain fatty acids, but the number of fatty acid chains differs between the two.
5. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
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