HESI A2
Anatomy and Physiology Hesi A2 Practice Test
1. Which of the heart's four chambers is the largest and the strongest?
- A. Right atrium
- B. Left ventricle
- C. Right ventricle
- D. Left atrium
Correct answer: B
Rationale: The left ventricle is the largest and strongest chamber of the heart. It pumps oxygenated blood to the body, making it vital for systemic circulation. The right atrium receives deoxygenated blood from the body, the right ventricle pumps this blood to the lungs, and the left atrium receives oxygenated blood from the lungs.
2. What is the role of the spleen in the immune system?
- A. To filter blood and remove old red blood cells
- B. To produce white blood cells
- C. To store lymphocytes
- D. To produce antibodies
Correct answer: A
Rationale: The spleen plays a crucial role in the immune system by filtering blood, specifically removing old or damaged red blood cells. It also stores lymphocytes, which are white blood cells that help fight infections. While the spleen does not produce white blood cells or antibodies, its main functions lie in blood filtration and storage of immune cells. Therefore, the correct answer is A. Choice B is incorrect because the spleen does not produce white blood cells. Choice C is incorrect as the spleen stores lymphocytes but does not primarily function to do so. Choice D is incorrect because the spleen does not produce antibodies.
3. Which hormone is involved in regulating the sleep-wake cycle?
- A. Insulin
- B. Melatonin
- C. Cortisol
- D. Thyroxine
Correct answer: B
Rationale: The correct answer is B: Melatonin. Melatonin, produced by the pineal gland, is the hormone involved in regulating the sleep-wake cycle. It plays a crucial role in signaling the body that it is time to sleep and is influenced by light exposure. Melatonin levels typically rise in the evening, promoting sleep, and decrease in the morning, helping in waking up. Choice A, Insulin, is involved in regulating blood sugar levels, not the sleep-wake cycle. Choice C, Cortisol, is a stress hormone that helps regulate metabolism and immune response but is not primarily involved in the sleep-wake cycle. Choice D, Thyroxine, is a hormone produced by the thyroid gland that regulates metabolism, growth, and development, but it is not directly involved in regulating the sleep-wake cycle.
4. Which structure in the kidney filters blood to form urine?
- A. Nephron
- B. Glomerulus
- C. Bowman's capsule
- D. Loop of Henle
Correct answer: B
Rationale: The glomerulus is a key structure in the kidney responsible for filtering blood. It consists of a network of capillaries that filter waste products and excess substances from the blood, allowing the formation of urine. While the nephron, Bowman's capsule, and Loop of Henle are also essential components of the kidney's filtration system, the glomerulus is specifically involved in the initial blood filtration process. The nephron is the functional unit of the kidney, Bowman's capsule surrounds the glomerulus and collects the filtrate, and the Loop of Henle is responsible for reabsorption and concentration of urine, not the initial blood filtration.
5. What is the main function of the immune system?
- A. To produce hormones
- B. To protect the body from infections
- C. To remove waste products
- D. To regulate body temperature
Correct answer: B
Rationale: The main function of the immune system is to protect the body from infections by identifying and destroying pathogens like bacteria and viruses. It plays a crucial role in maintaining overall health and preventing illnesses. Choice A is incorrect because hormone production is primarily handled by the endocrine system, not the immune system. Choice C is incorrect as waste removal is mainly performed by the excretory system, not the immune system. Choice D is incorrect as regulating body temperature is primarily the role of the thermoregulatory system, not the immune system.
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