HESI A2
HESI A2 Biology Practice Test
1. Genes control heredity in man and other organisms. This gene is ___
- A. A segment of DNA
- B. A bead-like structure on the chromosomes
- C. A protein molecule
- D. A segment of RNA
Correct answer: A
Rationale: Genes are sections of DNA that contain instructions for building and operating living organisms. These sections of DNA contain the genetic information that is passed on from one generation to the next. Genes are composed of specific sequences of nucleotides within the DNA molecule. Therefore, genes are best described as segments of DNA. Choice A is correct. Choice B is incorrect because genes are not bead-like structures on chromosomes but specific sequences of DNA. Choice C is incorrect because genes are not protein molecules but rather sequences of nucleotides. Choice D is incorrect because genes are not segments of RNA but DNA.
2. Which of the following types of hormones can diffuse through the cell membrane to bind to receptors inside the cell and stimulate a chemical response to a target cell?
- A. fat-soluble hormones
- B. amino acid derivatives
- C. hydrophilic hormones
- D. water-soluble hormones
Correct answer: A
Rationale: The correct answer is A: fat-soluble hormones. Fat-soluble hormones are able to diffuse through the cell membrane to bind to receptors inside the cell. This is because they are lipophilic, allowing them to cross the lipid bilayer easily. Once inside the cell, fat-soluble hormones can directly affect gene expression or cell function. Choice B, amino acid derivatives, and choice C, hydrophilic hormones, are not able to diffuse through the cell membrane as they are not lipophilic. Therefore, they cannot bind to receptors inside the cell. Choice D, water-soluble hormones, also cannot diffuse through the cell membrane as it is hydrophilic, making it unable to reach receptors inside the cell.
3. Which one of the following best describes the function of a cell membrane?
- A. It controls the substances entering and leaving the cell.
- B. It maintains the cell's shape.
- C. It controls the substances entering the cell.
- D. It supports the cell's structures.
Correct answer: A
Rationale: The correct answer is A. The function of a cell membrane is to control the substances entering and leaving the cell. The cell membrane is selectively permeable, allowing it to regulate the movement of ions and molecules in and out of the cell to maintain internal balance and proper function. Choice B is incorrect because while the cell membrane does provide some structural support, its primary function is not to maintain the cell's shape. Choice C is incorrect because the cell membrane controls both the substances entering and leaving the cell, not just those entering. Choice D is incorrect as the primary function of the cell membrane is not to support the cell's structures but to regulate the movement of substances.
4. Why is polarity the most important characteristic of water?
- A. the results of the polarity are hydrogen bonding, a high specific heat value, and its versatile solvent properties
- B. the results of the polarity are covalent bonding, a low specific heat value, and its versatile solvent properties
- C. the results of the polarity are ionic bonding, a high specific heat value, and its versatile solvent properties
- D. the results of the polarity are hydrogen bonding, a low specific heat value, and its versatile solvent properties
Correct answer: A
Rationale: Polarity is the most important characteristic of water because it results in hydrogen bonding, a high specific heat value, and its versatile solvent properties. These unique properties enable water to form hydrogen bonds with other substances, resist temperature changes, and dissolve a wide variety of solutes, making it essential for life processes. Choice B is incorrect because water exhibits hydrogen bonding, not covalent bonding. Choice C is incorrect as water does not form ionic bonds. Choice D is incorrect because water has a high, not low, specific heat value, which is vital for its role in temperature regulation.
5. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
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