HESI A2
HESI A2 Biology Practice Test
1. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
2. Why is it important for cells to undergo mitosis?
- A. mitosis allows for reproduction with male and female gametes
- B. mitosis increases variation within the species
- C. mitosis produces cells that are different from the parent cell
- D. mitosis produces cells for growth and repair of body tissue
Correct answer: D
Rationale: It is important for cells to undergo mitosis because it produces cells for the growth and repair of body tissues. Mitosis allows for the formation of genetically identical daughter cells, ensuring proper function and maintenance of the organism's body. By producing new cells, mitosis helps in the replenishment of damaged or worn-out tissue and supports overall growth and development. Choices A, B, and C are incorrect because mitosis is not directly related to reproduction with male and female gametes, increasing variation within the species, or producing cells different from the parent cell. These functions are more associated with meiosis, which is specifically for sexual reproduction and genetic diversity.
3. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
4. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
5. Why can animal cells use a contractile ring but plant cells cannot?
- A. Plant cells can use both methods to divide
- B. Animal cells divide faster, requiring them to pinch apart
- C. Plant cells are too rigid to use a contractile ring
- D. N/A
Correct answer: C
Rationale: Plant cells have a rigid cell wall surrounding them, which prevents them from using a contractile ring for cell division. The rigid cell wall requires plant cells to form a cell plate during cell division instead of pinching apart like animal cells with a contractile ring. Choice A is incorrect because plant cells cannot use a contractile ring due to their rigid cell wall. Choice B is incorrect as the speed of cell division is not the primary reason for the difference in cell division mechanisms between plant and animal cells. Choice D is not applicable as plant cells indeed have a specific limitation in using a contractile ring for cell division.
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