HESI A2
HESI A2 Biology Practice Test
1. Which of the following is true of Glycolysis?
- A. It requires the absence of Oxygen
- B. It occurs in the presence of Oxygen
- C. It is the final step of fermentation
- D. It is the final step of anaerobic respiration
Correct answer: B
Rationale: Glycolysis is the first step in cellular respiration and can occur in both aerobic (presence of oxygen) and anaerobic (absence of oxygen) conditions. In aerobic respiration, glycolysis takes place in the presence of oxygen and continues with the Krebs cycle and the electron transport chain. So, glycolysis does not require the absence of oxygen but can occur in its presence as part of the overall process of aerobic respiration. Choice A is incorrect because glycolysis can occur in the presence of oxygen. Choice C is incorrect because glycolysis is not the final step of fermentation; it is the initial step. Choice D is incorrect because glycolysis is not the final step of anaerobic respiration; it is the first step, followed by further processes to complete anaerobic respiration.
2. Which of the following bases is not present in RNA?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: B
Rationale: Thymine is not present in RNA. RNA uses uracil as one of its bases, which pairs with adenine. In RNA, adenine does not pair with thymine as in DNA. Cytosine and guanine are the other two bases found in both RNA and DNA.
3. Enzymes are typically _ _.
- A. Fats
- B. Proteins
- C. Sugars
- D. Neurons
Correct answer: B
Rationale: Enzymes are typically proteins that act as biological catalysts, speeding up chemical reactions in living organisms. While most enzymes are made of proteins, a few exceptions, known as ribozymes, are made of RNA. Proteins are composed of amino acids arranged in specific sequences that give enzymes their unique shape and functionality. Choice A, 'Fats,' is incorrect as enzymes are not typically composed of fats. Choice C, 'Sugars,' is incorrect as enzymes are not typically composed of sugars. Choice D, 'Neurons,' is incorrect as neurons are a type of cell in the nervous system, not typically associated with enzymes.
4. Which of the following is false?
- A. Animal cells use lysosomes to break down old cells
- B. Animal cells use chloroplasts to gain energy
- C. Plant cells have a cell wall to maintain structure
- D. All of the above are true
Correct answer: B
Rationale: The statement "B. Animal cells use chloroplasts to gain energy" is false. Chloroplasts are only present in plant cells and certain algae, where they are responsible for photosynthesis to generate energy from sunlight. Animal cells rely on other organelles, such as mitochondria, for energy production. Choice A is true because animal cells use lysosomes to break down old cells and cellular waste. Choice C is true as plant cells have a cell wall composed of cellulose that provides structural support and protection.
5. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
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