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HESI A2

HESI A2 Biology Practice Test

1. Where is DNA stored?

Correct answer: A

Rationale: DNA is stored in the nucleus of a cell. The nucleus houses the cell's genetic material, including the DNA, which contains the instructions for building and operating the cell. The nucleus controls the activities of the cell and is essential for proper cell function and reproduction. Ribosomes are responsible for protein synthesis, not DNA storage. The endoplasmic reticulum is involved in protein and lipid synthesis, storage, and transport but does not store DNA. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP, but they do not store DNA.

2. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.

3. What organelle pushes water out of the cell?

Correct answer: B

Rationale: The correct answer is B: Vacuoles (contractile). Vacuoles (contractile) are responsible for expelling excess water out of the cell. Lysosomes are involved in the digestion and removal of waste materials, mitochondria are the powerhouse of the cell involved in energy production, and the nucleus contains the cell's genetic material but does not play a role in pushing water out of the cell.

4. Which of the following structures is not directly involved in translation?

Correct answer: D

Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.

5. Why is DNA important for metabolic activities of the cell?

Correct answer: A

Rationale: The correct answer is A. DNA plays a crucial role in metabolic activities by controlling the synthesis of enzymes. Enzymes are the biological catalysts that regulate and facilitate metabolic reactions within the cell. Choice B is incorrect because DNA is not involved in stabilizing the cell wall; that role is usually associated with other components like the cell membrane. Choice C is incorrect as cell division is primarily regulated by different processes and molecules, not directly by DNA. Choice D is incorrect because DNA is not related to preventing the diffusion of nutrients; instead, it is involved in coding for proteins that aid in various cellular functions.

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