HESI A2
HESI A2 Biology Practice Test 2024
1. What molecule is primarily responsible for providing energy to the cell?
- A. ATP
- B. DNA
- C. ADP
- D. Glycogen
Correct answer: A
Rationale: Correct! ATP (Adenosine Triphosphate) is the main molecule that stores and provides energy for cellular activities. ATP is known as the energy currency of the cell, where energy released from the breakdown of nutrients is stored in the high-energy phosphate bonds of ATP. Choices B, C, and D are incorrect because DNA carries genetic information, ADP is the precursor of ATP, and glycogen is a polysaccharide used for energy storage, not direct energy provision.
2. Which is not a product of the Krebs cycle?
- A. ATP
- B. Carbon dioxide
- C. Glucose
- D. NADH
Correct answer: C
Rationale: Glucose is not a direct product of the Krebs cycle. Glucose is a starting molecule that undergoes glycolysis outside the mitochondria to produce pyruvate, which then enters the mitochondrial matrix to participate in the Krebs cycle. The Krebs cycle primarily generates ATP, carbon dioxide, and NADH as products. Choices A, B, and D are all products of the Krebs cycle, making them incorrect answers.
3. What happens during the S phase of the cell cycle?
- A. Chromosomes are duplicated.
- B. Cell growth occurs.
- C. DNA is synthesized.
- D. DNA is destroyed.
Correct answer: A
Rationale: During the S phase of the cell cycle, chromosomes are duplicated. This is a critical step in cell division as each chromosome is replicated to ensure that the resulting daughter cells receive an identical set of genetic information. Choices B, C, and D are incorrect because cell growth primarily occurs in the G1 phase, DNA synthesis happens during the S phase, and DNA destruction does not occur during any phase of the cell cycle.
4. Which of the following is necessary for cell diffusion?
- A. water
- B. membrane
- C. ATP
- D. gradient
Correct answer: D
Rationale: The correct answer is 'gradient.' In cell diffusion, substances move from an area of high concentration to an area of low concentration, driven by the concentration gradient. This process does not require water, membrane, or ATP specifically. Water can aid in the movement of substances, but it is not necessary for diffusion itself. The membrane is involved in regulating diffusion but is not a requirement for the process. ATP is not directly involved in simple diffusion processes; instead, it is more related to active transport mechanisms. Therefore, the concentration gradient is essential for cell diffusion to occur.
5. Select the option that best shows complementary base pairing in DNA:
- A. A and G
- B. A and C
- C. A and A
- D. A and T
Correct answer: D
Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.
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