HESI A2
Biology HESI A2 2024
1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
2. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.
- A. acidity
- B. shape
- C. chemistry
- D. substrate
Correct answer: B
Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.
3. Which of the following molecules is an important component of the plasma membrane?
- A. Phospholipids
- B. Steroids
- C. Sugars
- D. Amino acids
Correct answer: A
Rationale: Phospholipids are indeed a crucial component of the plasma membrane. They have a unique structure with hydrophilic heads and hydrophobic tails, which allows them to form the lipid bilayer of the membrane. Steroids, sugars, and amino acids are not primary components of the plasma membrane. Steroids are a different type of lipid, sugars are often found in glycoproteins on the membrane surface, and amino acids are the building blocks of proteins, some of which are membrane proteins, but not the membrane itself.
4. What is the composition of the plasma membrane?
- A. Proteins
- B. Lipids
- C. Carbohydrates
- D. Nucleotides
Correct answer: B
Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.
5. What type of tissue is fat?
- A. Connective
- B. Muscle
- C. Nervous
- D. Epithelial
Correct answer: A
Rationale: Fat is a type of loose connective tissue known as adipose tissue. Adipose tissue primarily functions to store energy and provide cushioning and insulation for organs. While muscle tissue is responsible for movement, nervous tissue transmits nerve impulses, and epithelial tissue covers and protects body surfaces, fat specifically falls under the category of connective tissue.
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