hemophilia is a sex linked trait carried on the x chromosome in an example of a male with hemophilia and a female carrier what ratio of the offspring
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HESI A2

Biology HESI A2 2024

1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.

2. What is the correct order of the hierarchy of levels in the biological classification of organisms?

Correct answer: A

Rationale: The correct order of the hierarchy of levels in the biological classification of organisms is Kingdom, Phylum, Class, Order, Family, Genus, and Species. This order is based on the Linnaean system of classification, with each level representing a progressively more specific grouping of organisms. Choice B is incorrect because it starts with Phylum instead of Kingdom. Choice C is incorrect as it places Order before Phylum. Choice D is incorrect because it does not follow the correct order of the biological classification hierarchy.

3. What happens during anaphase?

Correct answer: A

Rationale: During anaphase, the sister chromatids, joined at the centromere, separate and move towards opposite ends of the spindle apparatus. This movement ensures that each daughter cell receives an identical set of chromosomes. Choice B is incorrect as the disintegration of the nuclear membrane and nucleoli occurs during prophase. Choice C is incorrect as chromatids align at the center of the spindle during metaphase, not anaphase. Choice D is incorrect as the formation of the nuclear membrane and nucleoli occurs during telophase, not anaphase.

4. Which of the following is true of optical microscopy?

Correct answer: D

Rationale: The correct answer is D, 'More than one of the above is true.' Optical microscopy utilizes visible light (Choice B) and often involves the use of dyes for samples (Choice C). Using dyes helps enhance contrast, making it easier to visualize the structures being observed. Choice A is incorrect as optical microscopy does not utilize scanning electrons, but rather visible light.

5. How does asexual reproduction differ from sexual reproduction?

Correct answer: C

Rationale: Sexual reproduction involves two cells (gametes) that contribute genetic material to daughter cells, resulting in significantly greater genetic variation in the offspring. This genetic variation is essential for evolution and adaptation to environmental changes. In contrast, asexual reproduction involves one cell dividing to produce offspring that are genetically identical to the parent cell. Choice A is incorrect because sexual reproduction does not result in half of the cells being identical to the original cell; it involves two cells contributing genetic material. Choice B is incorrect because asexual reproduction does not result in significantly greater variation; it produces genetically identical offspring. Choice D is incorrect because sexual reproduction involves two cells contributing genetic material, not one cell yielding all identical cells.

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