HESI A2
Biology HESI A2 2024
1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
2. Which of the following is the structure of the male reproductive system that stores spermatozoa during the maturation process?
- A. vas deferens
- B. scrotum
- C. epididymis
- D. testicular artery
Correct answer: C
Rationale: The epididymis is the structure of the male reproductive system that stores spermatozoa during the maturation process. Sperm cells produced in the testes move to the epididymis, where they mature and become motile before being ejaculated. The vas deferens is responsible for transporting mature sperm to the urethra during ejaculation, the scrotum holds the testes and helps regulate their temperature for sperm production, and the testicular artery supplies blood to the testes. Therefore, choices A, B, and D are incorrect as they do not play a direct role in storing spermatozoa during the maturation process.
3. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
4. How should a researcher test the hypothesis that practicing yoga reduces blood pressure?
- A. Record the blood pressure of one male and one female participant before and after participating in a yoga class.
- B. Divide 30 female participants into two groups with similar average blood pressure; test each participant’s blood pressure after participating in a yoga class.
- C. Divide 30 female participants into two groups with similar average blood pressure; have one group watch television for an hour while the other takes a yoga class, record each participant’s blood pressure after the hour. Repeat daily for two weeks.
- D. Start with 15 men and 15 women; have the men watch television for an hour while the women take a yoga class, record each participant’s blood pressure after the hour. Reverse, having the men take a yoga class while the women watch television.
Correct answer: B
Rationale: Option B is the most appropriate way to test the hypothesis that practicing yoga reduces blood pressure. By dividing 30 female participants into two groups with similar average blood pressure levels and testing each participant's blood pressure after participating in a yoga class, the researcher can effectively evaluate the impact of yoga on blood pressure. This design allows for a comparison between the two groups, helping to isolate the effects of yoga practice on blood pressure. Option A only involves one male and one female participant, which may not provide a representative sample. Option C introduces an additional variable of watching television, which could confound the results. Option D lacks consistency in the experimental design by switching the activities between men and women, making it difficult to attribute any observed changes solely to yoga practice.
5. Which of the following arrangement is seen in the plasma membrane?
- A. Lipids with embedded proteins
- B. An outer lipid layer and an inner lipid layer
- C. Proteins embedded in lipid bilayer
- D. Altering protein and lipid layers
Correct answer: C
Rationale: The correct arrangement seen in the plasma membrane is proteins embedded in the lipid bilayer. The plasma membrane is composed of a lipid bilayer with embedded proteins. These proteins perform various functions such as transport, signaling, and structural support within the cell membrane. This arrangement allows for the selective permeability of the membrane and facilitates communication between the cell and its environment. Choices A, B, and D are incorrect because the primary arrangement in the plasma membrane involves proteins being embedded in the lipid bilayer, not lipids with embedded proteins, an outer and inner lipid layer, or altering protein and lipid layers.
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