hemophilia is a sex linked trait carried on the x chromosome in an example of a male with hemophilia and a female carrier what ratio of the offspring
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HESI A2

Biology HESI A2 2024

1. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.

2. Which of the following is true of heterozygous traits?

Correct answer: D

Rationale: Heterozygous traits are denoted by having two different alleles for a particular gene, represented as Aa. This means that they are not haploid (A), not denoted AA (B), and not denoted aa (C). Therefore, the correct answer is D, as heterozygous traits are represented as Aa.

3. In an example of a male with hemophilia and a female carrier, what percentage of the offspring is predicted to be carriers only?

Correct answer: C

Rationale: In this scenario, the male offspring will inherit the X chromosome with the hemophilia gene from the mother, as males have one X chromosome inherited from their mother. The female offspring will inherit one normal X chromosome from the father and one X chromosome with the hemophilia gene from the mother, making them carriers of the hemophilia trait. Therefore, 50% of the offspring will be carriers only. Option A (0%) is incorrect as female offspring will inherit the X chromosome with the hemophilia gene from the mother. Option B (25%) is incorrect as the female offspring will not be unaffected. Option D (100%) is incorrect as not all offspring will be carriers, only the female offspring.

4. Where is the genetic information of a eukaryotic cell stored?

Correct answer: B

Rationale: The correct answer is B: Nucleus. In eukaryotic cells, genetic information (DNA) is stored in the nucleus. This organelle acts as the control center of the cell, housing the DNA and regulating gene expression. Choices A, C, and D are incorrect because the genetic information is not stored in the mitochondria, Golgi Apparatus, or cytoplasm. The mitochondria are responsible for energy production, the Golgi Apparatus is involved in protein processing and packaging, and the cytoplasm is where various cellular activities take place, but none of these organelles store the genetic information.

5. Which of the following is not a product of the Krebs cycle?

Correct answer: B

Rationale: The correct answer is B: oxygen. Oxygen is not a product of the Krebs cycle. During the Krebs cycle, carbon dioxide, adenosine triphosphate (ATP), and energy carriers like NADH and FADH2 are produced. Carbon dioxide is a byproduct of the cycle, ATP is a form of energy produced, and energy carriers play a crucial role in transferring energy within the cell. Therefore, oxygen is the only option that is not a product of the Krebs cycle, making it the correct answer.

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