HESI A2
HESI A2 Biology Practice Test 2024
1. What is the most important component of the cell, contributing to protection, communication, and the passage of substances?
- A. Cytoplasm
- B. Cell Membrane
- C. Cytoskeleton
- D. Vacuole
Correct answer: B
Rationale: The cell membrane is the correct answer. It is the most important component of the cell as it provides protection, facilitates communication, and regulates the passage of substances in and out of the cell. The cytoplasm (Choice A) is the gel-like substance within the cell that holds organelles, but it is not primarily responsible for the functions mentioned in the question. The cytoskeleton (Choice C) provides structural support to the cell but is not directly involved in protection, communication, or substance passage. Vacuoles (Choice D) are responsible for storage and maintaining turgor pressure but do not play a primary role in the functions specified in the question.
2. What type of transport moves substances across the cell membrane using energy?
- A. Passive Transport
- B. Active Transport
- C. Facilitated Diffusion
- D. Osmosis
Correct answer: B
Rationale: The correct answer is B: Active Transport. Active transport moves substances across the cell membrane by utilizing energy from the cell, typically in the form of ATP. This process allows the cell to move molecules against their concentration gradient, requiring energy expenditure. Choices A, C, and D are incorrect because passive transport does not require energy input, facilitated diffusion involves the assistance of proteins but does not directly use energy, and osmosis is the diffusion of water molecules specifically, not substances, across a selectively permeable membrane.
3. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
4. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
5. Why is DNA important for metabolic activities of the cell?
- A. It controls the synthesis of enzymes.
- B. It stabilizes the cell wall.
- C. It initiates cell division.
- D. It prevents diffusion of nutrients.
Correct answer: A
Rationale: The correct answer is A. DNA plays a crucial role in metabolic activities by controlling the synthesis of enzymes. Enzymes are the biological catalysts that regulate and facilitate metabolic reactions within the cell. Choice B is incorrect because DNA is not involved in stabilizing the cell wall; that role is usually associated with other components like the cell membrane. Choice C is incorrect as cell division is primarily regulated by different processes and molecules, not directly by DNA. Choice D is incorrect because DNA is not related to preventing the diffusion of nutrients; instead, it is involved in coding for proteins that aid in various cellular functions.
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