HESI A2
HESI A2 Biology 2024
1. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
2. Dogs are part of a larger animal group, the Carnivora. What classification is this?
- A. Kingdom
- B. Class
- C. Order
- D. Genus
Correct answer: C
Rationale: The classification 'Carnivora' refers to an order in the taxonomic hierarchy. In the Linnaean classification system, the order comes below the class but above the family level. Therefore, Carnivora is a higher classification that includes dog species as well as other carnivorous mammals like cats, bears, and weasels. Option A (Kingdom) is too broad and refers to the highest taxonomic rank. Option B (Class) is a lower taxonomic rank than order. Option D (Genus) is a much more specific rank that comes below the family level in the Linnaean hierarchy.
3. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
4. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
5. Why do cells need to use exocytosis?
- A. To obtain energy
- B. To defend against invaders
- C. To remove waste products
- D. To undergo division
Correct answer: C
Rationale: Cells need to use exocytosis to remove waste products from the cell. Exocytosis is a process where cells release molecules or substances outside the cell by fusing vesicles with the cell membrane. This process is crucial for maintaining cellular homeostasis by efficiently eliminating waste materials. Choices A, B, and D are incorrect because exocytosis is specifically involved in the expulsion of molecules, not for obtaining energy, defending against invaders, or cell division.
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