HESI A2
Biology HESI A2 2024
1. During which phase of cell division do the chromosomes replicate?
- A. Prophase
- B. Interphase
- C. Anaphase
- D. Telophase
Correct answer: B
Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.
2. Cytosine and thymine are known as:
- A. Purines
- B. Pyrimidines
- C. Both
- D. None of the above
Correct answer: B
Rationale: Cytosine and thymine are known as pyrimidines because they have a single carbon ring structure. Purines, on the other hand, have a double-ring structure. Choice A ('Purines') is incorrect because purines have a double-ring structure, unlike cytosine and thymine. Choice C ('Both') is incorrect as it implies they are both purines and pyrimidines, which is not true. Choice D ('None of the above') is incorrect because cytosine and thymine are indeed pyrimidines.
3. DNA bases include all but which of the following?
- A. Adenine
- B. Thymine
- C. Uracil
- D. Cytosine
Correct answer: C
Rationale: The correct answer is C: Uracil. Uracil is not a DNA base; it is a base found only in RNA. The four bases in DNA are Adenine, Thymine, Cytosine, and Guanine. Choice A, Adenine, is a correct DNA base. Choice B, Thymine, is a correct DNA base. Choice D, Cytosine, is a correct DNA base. Therefore, Uracil is the only incorrect choice among the options provided.
4. During which phase of mitosis do the chromosomes align in the center of the cell?
- A. Prophase
- B. Metaphase
- C. Telophase
- D. Anaphase
Correct answer: B
Rationale: The correct answer is Metaphase. During Metaphase, the chromosomes line up along the center of the cell's equator, forming the metaphase plate. This alignment ensures that during the subsequent phase, Anaphase, the sister chromatids can separate and move towards opposite poles. Prophase is the initial phase of mitosis where chromosomes condense and the nuclear envelope breaks down. Telophase is the final phase of mitosis where two new nuclei form.
5. Which of the following organelles are responsible for producing cell energy?
- A. Mitochondrion and chloroplast
- B. Mitochondrion and nucleus
- C. Chloroplast and nucleus
- D. Chloroplast and lysosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion and chloroplast. Mitochondria and chloroplasts are the organelles responsible for producing cell energy through cellular respiration and photosynthesis, respectively. Choice B is incorrect because the nucleus is not involved in energy production. Choice C is incorrect as the nucleus is not an organelle that produces energy. Choice D is incorrect as lysosomes function in digesting waste materials, not in energy production.
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