Nursing Elites

1. During which phase of cell division do the chromosomes replicate?

• A. Prophase
• B. Interphase
• C. Anaphase
• D. Telophase

Correct answer: B

Rationale: Chromosomes replicate during the interphase of the cell cycle. Interphase is the phase where the cell prepares for division by undergoing various activities such as growth, DNA replication, and protein synthesis. During DNA replication in interphase, each chromosome in the cell is duplicated to form two sister chromatids, which are then separated during cell division. Prophase is the phase where the chromosomes condense, and the nuclear envelope breaks down. Anaphase is the phase where sister chromatids are pulled apart towards opposite poles of the cell. Telophase is the phase where the nuclear envelope reforms, and chromosomes begin to decondense.

2. Where is the genetic information of a eukaryotic cell stored?

• A. Mitochondria
• B. Nucleus
• C. Golgi Apparatus
• D. Cytoplasm

Correct answer: B

Rationale: The correct answer is B: Nucleus. In eukaryotic cells, genetic information (DNA) is stored in the nucleus. This organelle acts as the control center of the cell, housing the DNA and regulating gene expression. Choices A, C, and D are incorrect because the genetic information is not stored in the mitochondria, Golgi Apparatus, or cytoplasm. The mitochondria are responsible for energy production, the Golgi Apparatus is involved in protein processing and packaging, and the cytoplasm is where various cellular activities take place, but none of these organelles store the genetic information.

3. The phases of mitosis include:

• A. Prophase, interphase, metaphase, anaphase, and telophase
• B. Prophase, prophase, metaphase, anaphase, and cytokinesis
• C. Prophase, prometaphase, metaphase, anaphase, and telophase
• D. Prophase, interphase, prophase, anaphase, and telophase

Correct answer: C

Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.

4. During protein synthesis, what process uses an RNA strand to produce a complementary strand of DNA?

• A. Transcription
• B. Translation
• C. Transfer synthesis
• D. Codon synthesis

Correct answer: A

Rationale: The correct answer is 'Transcription.' During transcription, an RNA strand is used to produce a complementary strand of DNA. This process is essential for converting the genetic information stored in DNA into RNA. Choice B, 'Translation,' is incorrect as it involves the synthesis of proteins from mRNA. Choice C, 'Transfer synthesis,' is not a recognized term in molecular biology. Choice D, 'Codon synthesis,' is also incorrect as it does not refer to the process of using an RNA strand to produce a complementary DNA strand.

5. What kind of bond connects sugar and phosphate in DNA?

• A. hydrogen
• B. ionic
• C. covalent
• D. overt

Correct answer: C

Rationale: Sugar and phosphate are indeed connected by covalent bonds in DNA. Covalent bonds involve the sharing of electrons between atoms, which is essential for forming the backbone of the DNA molecule. Hydrogen bonds (Choice A) are important in holding the nitrogenous bases together in the DNA double helix but do not connect sugar and phosphate. Ionic bonds (Choice B) involve the transfer of electrons between atoms and are not the primary bond connecting sugar and phosphate in DNA. 'Overt' (Choice D) is not a type of chemical bond and is an incorrect distractor.

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