HESI A2
Biology HESI A2 Practice Test
1. Which is true of gametes?
- A. They are diploid cells
- B. They are haploid cells
- C. They are somatic
- D. A & C are true
Correct answer: B
Rationale: Gametes are sex cells (sperm and eggs) that are involved in sexual reproduction. They are haploid cells, meaning they have half the number of chromosomes (n) compared to diploid cells. This is necessary for the formation of a diploid zygote when two gametes unite during fertilization. Somatic cells are non-reproductive cells in the body, so they are not gametes. Choice A is incorrect because gametes are not diploid but haploid. Choice C is incorrect because gametes are not somatic cells.
2. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
3. Why can animal cells use a contractile ring but plant cells cannot?
- A. Plant cells can use both methods to divide
- B. Animal cells divide faster, requiring them to pinch apart
- C. Plant cells are too rigid to use a contractile ring
- D. N/A
Correct answer: C
Rationale: Plant cells have a rigid cell wall surrounding them, which prevents them from using a contractile ring for cell division. The rigid cell wall requires plant cells to form a cell plate during cell division instead of pinching apart like animal cells with a contractile ring. Choice A is incorrect because plant cells cannot use a contractile ring due to their rigid cell wall. Choice B is incorrect as the speed of cell division is not the primary reason for the difference in cell division mechanisms between plant and animal cells. Choice D is not applicable as plant cells indeed have a specific limitation in using a contractile ring for cell division.
4. Which organelle is responsible for detoxifying harmful substances in the cell?
- A. Endoplasmic Reticulum
- B. Lysosomes
- C. Peroxisomes
- D. Golgi Apparatus
Correct answer: C
Rationale: The correct answer is C, Peroxisomes. Peroxisomes are responsible for detoxifying harmful substances in the cell by breaking down fatty acids and producing hydrogen peroxide. This process helps protect the cell from damage caused by toxic substances. Choice A, Endoplasmic Reticulum, is involved in protein and lipid synthesis, not detoxification. Choice B, Lysosomes, contain enzymes for digestion and waste removal, not primarily detoxification. Choice D, Golgi Apparatus, is responsible for modifying, sorting, and packaging proteins for secretion, not detoxification.
5. What is the role of tRNA during protein synthesis?
- A. Carries amino acids to the ribosome
- B. Links nucleotides together
- C. Copies DNA sequences
- D. Replicates genetic material
Correct answer: A
Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.
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