HESI A2
HESI A2 Biology 2024
1. Which animal has an open transport system?
- A. Grasshopper
- B. Earthworm
- C. Dolphin
- D. Chicken
Correct answer: B
Rationale: The correct answer is B: Earthworm. Earthworms have an open circulatory system, meaning their blood and interstitial fluid are not enclosed in blood vessels. Instead, the blood flows freely within the body cavity, allowing for direct exchange of nutrients and waste products with surrounding tissues. This lack of a closed transport system is a characteristic feature of earthworms. Choices A, C, and D are incorrect because grasshoppers, dolphins, and chickens have closed circulatory systems where the blood is enclosed within blood vessels, unlike earthworms.
2. When the genotype consists of a dominant and a recessive allele, the phenotype will be like the _ allele.
- A. Dominant
- B. Recessive
- C. Both
- D. Neither
Correct answer: A
Rationale: When the genotype consists of a dominant and a recessive allele, the phenotype will be like the dominant allele. This is because dominant alleles typically mask the expression of recessive alleles. Therefore, the dominant allele will be expressed in the phenotype in most basic cases. The recessive allele will only be expressed phenotypically if the individual is homozygous recessive. Choice B, 'Recessive,' is incorrect because the phenotype will not be like the recessive allele in this case. Choice C, 'Both,' is incorrect because in simple dominant-recessive inheritance, the dominant allele will overshadow the recessive allele. Choice D, 'Neither,' is incorrect as the phenotype will resemble the dominant allele.
3. The two catabolic pathways that lead to cellular energy production are:
- A. fermentation and protein synthesis
- B. cellular respiration and glycolysis
- C. fermentation and glycolysis
- D. cellular respiration and fermentation
Correct answer: D
Rationale: The correct answer is D: cellular respiration and fermentation. Cellular respiration involves the breakdown of glucose in the presence of oxygen to produce ATP, which is the primary source of energy for cells. Fermentation, on the other hand, occurs in the absence of oxygen and produces ATP through glycolysis followed by specific fermentation pathways. Choices A, B, and C are incorrect. Protein synthesis is a biosynthetic process, not a catabolic pathway for energy production. Glycolysis is a common step in both cellular respiration and fermentation, so it is not a pair of distinct catabolic pathways. Therefore, the most accurate pairing of catabolic pathways for cellular energy production is cellular respiration and fermentation.
4. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
5. How many chromosomes do sperm and egg produce in meiosis?
- A. 23
- B. 46
- C. 25
- D. 50
Correct answer: A
Rationale: During meiosis, sperm and egg cells produce half the number of chromosomes found in somatic cells. Each contributes 23 chromosomes, which combine to form a zygote with a total of 46 chromosomes. Choice B (46) is incorrect because this is the number of chromosomes produced in mitosis, not meiosis. Choices C (25) and D (50) are also incorrect as they do not align with the chromosome count in sex cells during meiosis.
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