HESI A2
Biology HESI A2 Practice Test
1. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
2. During protein synthesis, what process uses an RNA strand to produce a complementary strand of DNA?
- A. Transcription
- B. Translation
- C. Transfer synthesis
- D. Codon synthesis
Correct answer: A
Rationale: The correct answer is 'Transcription.' During transcription, an RNA strand is used to produce a complementary strand of DNA. This process is essential for converting the genetic information stored in DNA into RNA. Choice B, 'Translation,' is incorrect as it involves the synthesis of proteins from mRNA. Choice C, 'Transfer synthesis,' is not a recognized term in molecular biology. Choice D, 'Codon synthesis,' is also incorrect as it does not refer to the process of using an RNA strand to produce a complementary DNA strand.
3. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
4. Genes control heredity in man and other organisms. This gene is ___
- A. A segment of DNA
- B. A bead-like structure on the chromosomes
- C. A protein molecule
- D. A segment of RNA
Correct answer: A
Rationale: Genes are sections of DNA that contain instructions for building and operating living organisms. These sections of DNA contain the genetic information that is passed on from one generation to the next. Genes are composed of specific sequences of nucleotides within the DNA molecule. Therefore, genes are best described as segments of DNA. Choice A is correct. Choice B is incorrect because genes are not bead-like structures on chromosomes but specific sequences of DNA. Choice C is incorrect because genes are not protein molecules but rather sequences of nucleotides. Choice D is incorrect because genes are not segments of RNA but DNA.
5. Which of the following is not found within a bacterial cell?
- A. mitochondria
- B. DNA
- C. vesicles
- D. ribosome
Correct answer: A
Rationale: The correct answer is A: mitochondria. Mitochondria are not found in bacterial cells. Bacterial cells lack membrane-bound organelles like mitochondria, which are commonly found in eukaryotic cells. Choices B, C, and D are all components that can be found within a bacterial cell. Bacterial cells contain DNA as their genetic material, vesicles for various cellular functions, and ribosomes for protein synthesis. Therefore, the presence of mitochondria is the distinguishing factor that is not found in bacterial cells, making option A the correct answer.
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