HESI A2
HESI A2 Biology Practice Test
1. Prokaryotic cells:
- A. Have a nucleus
- B. Have a capsule
- C. Have membrane-bound organelles
- D. Cannot move on their own
Correct answer: B
Rationale: Prokaryotic cells do not have a nucleus or membrane-bound organelles. One characteristic feature of prokaryotic cells is the presence of a capsule, which is a protective layer outside the cell wall. This capsule helps the prokaryotic cell adhere to surfaces, evade the host immune system, and protect against desiccation. Choice A is incorrect because prokaryotic cells lack a nucleus. Choice C is incorrect as prokaryotic cells do not have membrane-bound organelles. Choice D is incorrect as prokaryotic cells can move using structures like flagella or pili.
2. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
3. The two catabolic pathways that lead to cellular energy production are:
- A. fermentation and protein synthesis
- B. cellular respiration and glycolysis
- C. fermentation and glycolysis
- D. cellular respiration and fermentation
Correct answer: D
Rationale: The correct answer is D: cellular respiration and fermentation. Cellular respiration involves the breakdown of glucose in the presence of oxygen to produce ATP, which is the primary source of energy for cells. Fermentation, on the other hand, occurs in the absence of oxygen and produces ATP through glycolysis followed by specific fermentation pathways. Choices A, B, and C are incorrect. Protein synthesis is a biosynthetic process, not a catabolic pathway for energy production. Glycolysis is a common step in both cellular respiration and fermentation, so it is not a pair of distinct catabolic pathways. Therefore, the most accurate pairing of catabolic pathways for cellular energy production is cellular respiration and fermentation.
4. Which organelle is the site of photosynthesis in plant cells?
- A. Mitochondria
- B. Chloroplasts
- C. Ribosomes
- D. Endoplasmic Reticulum
Correct answer: B
Rationale: The correct answer is B: Chloroplasts. Chloroplasts are responsible for conducting photosynthesis in plant cells. They contain chlorophyll, a pigment that captures light energy and converts it into chemical energy through the process of photosynthesis. Mitochondria (choice A) are known as the powerhouse of the cell and are involved in cellular respiration, not photosynthesis. Ribosomes (choice C) are responsible for protein synthesis. The endoplasmic reticulum (choice D) is involved in protein and lipid synthesis and transport within the cell, not photosynthesis.
5. Which of the following describes how a bacterium reproduces?
- A. Mitosis
- B. Meiosis
- C. Binary fission
- D. Cytokinesis
Correct answer: C
Rationale: Bacteria reproduce through a process called 'binary fission.' During binary fission, a bacterium duplicates its DNA and then divides into two identical daughter cells. This method is the primary way bacteria replicate. Choice A, 'Mitosis,' is incorrect because mitosis is a process specific to eukaryotic cells, where the nucleus divides to produce two identical nuclei. Choice B, 'Meiosis,' is incorrect as meiosis is a specialized type of cell division that produces gametes with half the chromosome number. Choice D, 'Cytokinesis,' is not the correct answer as cytokinesis is the physical process of cell division, which occurs after the genetic material has been divided in mitosis or meiosis.
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