HESI A2
HESI A2 Biology 2024
1. If bacteria are placed in a strong solution of salt water, they will shrink as water moves out of the bacteria. What is this process called?
- A. Dehydration synthesis
- B. Hydrolysis
- C. Osmosis
- D. Isotonic transport
Correct answer: C
Rationale: Osmosis is the process by which water molecules move across a semipermeable membrane from an area of lower solute concentration to an area of higher solute concentration. In this case, when bacteria are placed in a strong solution of salt water, the high concentration of solutes outside the bacteria causes water to move out of the bacteria, leading to shrinkage. This process is known as osmosis. Dehydration synthesis (Choice A) is a process where molecules combine by removing water. Hydrolysis (Choice B) is the breakdown of molecules by the addition of water. Isotonic transport (Choice D) does not accurately describe the specific movement of water in or out of bacterial cells in a hypertonic solution.
2. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
3. How should a researcher test the hypothesis that practicing yoga reduces blood pressure?
- A. Record the blood pressure of one male and one female participant before and after participating in a yoga class.
- B. Divide 30 female participants into two groups with similar average blood pressure; test each participant’s blood pressure after participating in a yoga class.
- C. Divide 30 female participants into two groups with similar average blood pressure; have one group watch television for an hour while the other takes a yoga class, record each participant’s blood pressure after the hour. Repeat daily for two weeks.
- D. Start with 15 men and 15 women; have the men watch television for an hour while the women take a yoga class, record each participant’s blood pressure after the hour. Reverse, having the men take a yoga class while the women watch television.
Correct answer: B
Rationale: Option B is the most appropriate way to test the hypothesis that practicing yoga reduces blood pressure. By dividing 30 female participants into two groups with similar average blood pressure levels and testing each participant's blood pressure after participating in a yoga class, the researcher can effectively evaluate the impact of yoga on blood pressure. This design allows for a comparison between the two groups, helping to isolate the effects of yoga practice on blood pressure. Option A only involves one male and one female participant, which may not provide a representative sample. Option C introduces an additional variable of watching television, which could confound the results. Option D lacks consistency in the experimental design by switching the activities between men and women, making it difficult to attribute any observed changes solely to yoga practice.
4. Which of the following is true of Glycolysis?
- A. It requires the absence of Oxygen
- B. It occurs in the presence of Oxygen
- C. It is the final step of fermentation
- D. It is the final step of anaerobic respiration
Correct answer: B
Rationale: Glycolysis is the first step in cellular respiration and can occur in both aerobic (presence of oxygen) and anaerobic (absence of oxygen) conditions. In aerobic respiration, glycolysis takes place in the presence of oxygen and continues with the Krebs cycle and the electron transport chain. So, glycolysis does not require the absence of oxygen but can occur in its presence as part of the overall process of aerobic respiration. Choice A is incorrect because glycolysis can occur in the presence of oxygen. Choice C is incorrect because glycolysis is not the final step of fermentation; it is the initial step. Choice D is incorrect because glycolysis is not the final step of anaerobic respiration; it is the first step, followed by further processes to complete anaerobic respiration.
5. Which of the following types of hormones can diffuse through the cell membrane to bind to receptors inside the cell and stimulate a chemical response to a target cell?
- A. fat-soluble hormones
- B. amino acid derivatives
- C. hydrophilic hormones
- D. water-soluble hormones
Correct answer: A
Rationale: The correct answer is A: fat-soluble hormones. Fat-soluble hormones are able to diffuse through the cell membrane to bind to receptors inside the cell. This is because they are lipophilic, allowing them to cross the lipid bilayer easily. Once inside the cell, fat-soluble hormones can directly affect gene expression or cell function. Choice B, amino acid derivatives, and choice C, hydrophilic hormones, are not able to diffuse through the cell membrane as they are not lipophilic. Therefore, they cannot bind to receptors inside the cell. Choice D, water-soluble hormones, also cannot diffuse through the cell membrane as it is hydrophilic, making it unable to reach receptors inside the cell.
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