HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. The renal system consists of all the organs involved in the formation and release of urine and includes the kidneys, ureters, bladder, and urethra.
- A. The digestive system
- B. The reproductive system
- C. The renal system
- D. The kidney system
Correct answer: C
Rationale: The correct term for the system involving the organs responsible for the formation and release of urine is the renal system, not the digestive or reproductive system. The kidneys, ureters, bladder, and urethra are specifically part of the renal system, which is responsible for filtering the blood to remove waste and excess fluids, producing urine, and eliminating it from the body. The other choices, the digestive system and the reproductive system, are not responsible for the formation and release of urine, making them incorrect answers.
3. Which organelle is involved in the synthesis of proteins?
- A. Endoplasmic Reticulum
- B. Ribosomes
- C. Lysosomes
- D. Vacuoles
Correct answer: B
Rationale: Ribosomes are the organelles involved in the synthesis of proteins. They are the cellular machinery responsible for translating mRNA into proteins, making them essential for cell function and structure. The other organelles listed, such as the Endoplasmic Reticulum, Lysosomes, and Vacuoles, have different functions unrelated to protein synthesis. The Endoplasmic Reticulum plays a role in protein processing and transport, Lysosomes are involved in digestion and waste removal, and Vacuoles are responsible for storage and maintaining cell turgor pressure.
4. If a hard-boiled egg is placed in a beaker of saltwater, what will happen to the egg?
- A. Expand because water will move into the egg
- B. Shrivel because water will leave the egg
- C. Remain the same
- D. None of the above
Correct answer: B
Rationale: The correct answer is B. When a hard-boiled egg is placed in a beaker of saltwater, the egg will shrivel because water will leave the egg through osmosis. Osmosis is the movement of water from an area of lower solute concentration to an area of higher solute concentration, in this case, from the egg into the saltwater. The higher concentration of solute in the saltwater causes water to move out of the egg, leading to the egg shrinking or shriveling. Choices A, C, and D are incorrect because the egg will not expand, remain the same, or have an outcome different from shriveling when placed in a beaker of saltwater.
5. The apical side of an epithelial cell:
- A. Is exposed to fluid or air
- B. Is on the bottom side of the cell
- C. Does not allow any substances to pass through
- D. None of the above
Correct answer: A
Rationale: The apical side of an epithelial cell is the top side, which is typically exposed to fluids, air, or the inside of an organ. This side allows substances to pass through it, facilitating the absorption, secretion, or excretion of various substances. Choice B is incorrect as the apical side is not on the bottom but the top side. Choice C is incorrect as the apical side does allow substances to pass through. Choice D is incorrect as there are characteristics associated with the apical side.
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