HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. How many different types of nucleotides are there in DNA?
- A. one
- B. two
- C. four
- D. eight
Correct answer: C
Rationale: The correct answer is 'C: four.' DNA is composed of four different types of nucleotides: adenine, thymine, guanine, and cytosine. These nucleotides pair up in specific combinations to form the genetic code. Choices 'A: one,' 'B: two,' and 'D: eight' are incorrect because DNA consists of a set of four distinct nucleotides, not one, two, or eight.
3. Which structure controls the passage of substances into and out of the cell?
- A. Vacuole
- B. Cell Membrane
- C. Nuclear Membrane
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the Cell Membrane. The cell membrane acts as a barrier that controls the passage of substances into and out of the cell. It is selectively permeable, allowing only certain molecules to pass through. Vacuole (Choice A), Nuclear Membrane (Choice C), and Cytoplasm (Choice D) do not primarily regulate the passage of substances in and out of the cell. Vacuoles are responsible for storage, the nuclear membrane surrounds the nucleus providing protection, and the cytoplasm is the fluid where organelles are suspended.
4. What is the composition of the plasma membrane?
- A. Proteins
- B. Lipids
- C. Carbohydrates
- D. Nucleotides
Correct answer: B
Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.
5. What is the main function of the ribosomes in the cell?
- A. DNA Replication
- B. Protein Synthesis
- C. Lipid Breakdown
- D. Cell Division
Correct answer: B
Rationale: The correct answer is B: Protein Synthesis. Ribosomes are cellular organelles responsible for synthesizing proteins. This process is crucial for various cellular functions. Choice A, DNA Replication, is incorrect as ribosomes are not involved in this process. Choice C, Lipid Breakdown, is also incorrect as ribosomes do not play a role in lipid metabolism. Choice D, Cell Division, is incorrect as ribosomes are not directly involved in the process of cell division.
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