HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. In the scientific process, which of the following is a statement or explanation of certain events or happenings?
- A. hypothesis
- B. observation
- C. experiment
- D. conclusion
Correct answer: A
Rationale: A hypothesis is a statement or explanation of certain events or phenomena based on observations and prior knowledge. It is a testable prediction that guides the scientific investigation process. By formulating a hypothesis, scientists can make predictions and design experiments to gather data and test the validity of the hypothesis. Observations (choice B) involve gathering information through the senses. Experiments (choice C) are procedures carried out to support or refute a hypothesis. Conclusions (choice D) are deductions made based on the results of experiments and observations, but they are not the initial statement or explanation of events or happenings.
3. Enzymes can _ reactions.
- A. Catalyze
- B. Inhibit
- C. Stop
- D. None of the above
Correct answer: A
Rationale: Enzymes function as catalysts that promote and accelerate chemical reactions in biological systems. They do this by lowering the activation energy required for the reactions to occur, thereby speeding up the process without being consumed in the reaction. Enzymes facilitate reactions rather than inhibiting or stopping them. Therefore, the correct answer is 'Catalyze.' 'Inhibit' and 'Stop' are incorrect because enzymes do not hinder or halt reactions but rather enhance them.
4. Which of the following are found both in open and closed circulatory systems?
- A. Arteries
- B. Red blood cells
- C. Capillaries
- D. Immune cells
Correct answer: C
Rationale: The correct answer is C, Capillaries. Capillaries are found in both open and closed circulatory systems. Capillaries are small blood vessels that connect arteries and veins, allowing for the exchange of nutrients and wastes between the blood and tissues. They are essential components of circulatory systems regardless of whether they are open or closed. Arteries (Choice A) are not found in open circulatory systems, as these systems lack distinct arteries and veins. Red blood cells (Choice B) are present in the blood but are not exclusive to either open or closed circulatory systems. Immune cells (Choice D) are not specific components of circulatory systems, as they are part of the immune system.
5. Which of the following is not a product of the Krebs cycle?
- A. carbon dioxide
- B. oxygen
- C. adenosine triphosphate (ATP)
- D. energy carriers
Correct answer: B
Rationale: The correct answer is B: oxygen. Oxygen is not a product of the Krebs cycle. During the Krebs cycle, carbon dioxide, adenosine triphosphate (ATP), and energy carriers like NADH and FADH2 are produced. Carbon dioxide is a byproduct of the cycle, ATP is a form of energy produced, and energy carriers play a crucial role in transferring energy within the cell. Therefore, oxygen is the only option that is not a product of the Krebs cycle, making it the correct answer.
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