HESI A2
HESI A2 Biology 2024
1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
2. When the genotype consists of a dominant and a recessive allele, the phenotype will be like the _ allele.
- A. Dominant
- B. Recessive
- C. Both
- D. Neither
Correct answer: A
Rationale: When the genotype consists of a dominant and a recessive allele, the phenotype will be like the dominant allele. This is because dominant alleles typically mask the expression of recessive alleles. Therefore, the dominant allele will be expressed in the phenotype in most basic cases. The recessive allele will only be expressed phenotypically if the individual is homozygous recessive. Choice B, 'Recessive,' is incorrect because the phenotype will not be like the recessive allele in this case. Choice C, 'Both,' is incorrect because in simple dominant-recessive inheritance, the dominant allele will overshadow the recessive allele. Choice D, 'Neither,' is incorrect as the phenotype will resemble the dominant allele.
3. In a phospholipid molecule, the head:
- A. Is hydrophilic
- B. Is hydrophobic
- C. Is on the inner side of the layer
- D. Both A and C
Correct answer: D
Rationale: The head of a phospholipid is hydrophilic (water-loving) and is located on the outer side of the lipid bilayer, interacting with water molecules. This arrangement positions the hydrophobic tails inward, away from water. Therefore, the correct answer is D. Choice A is incorrect because the head is hydrophilic, not hydrophobic. Choice B is incorrect as the head is on the outer side, not the inner side of the layer.
4. What is the process of cell division that results in two daughter cells with identical genetic material?
- A. Mitosis
- B. Meiosis
- C. Binary Fission
- D. Budding
Correct answer: A
Rationale: The correct answer is A, Mitosis. Mitosis is the process of cell division in which a cell divides and produces two daughter cells that are genetically identical to the parent cell. Choice B, Meiosis, is a type of cell division that produces gametes with half the number of chromosomes. Choice C, Binary Fission, is a form of asexual reproduction in single-celled organisms. Choice D, Budding, is a form of asexual reproduction where a new organism develops from an outgrowth or bud on the parent.
5. What type of cell is an animal cell?
- A. Prokaryotic
- B. Eukaryotic
- C. Plant Cell
- D. Bacterial Cell
Correct answer: B
Rationale: The correct answer is B, eukaryotic. Animal cells are classified as eukaryotic cells because they contain membrane-bound organelles such as the nucleus, mitochondria, and endoplasmic reticulum. Choice A, prokaryotic, is incorrect as prokaryotic cells lack membrane-bound organelles. Choice C, Plant Cell, is incorrect as the question specifically asks about animal cells. Choice D, Bacterial Cell, is incorrect as bacteria are prokaryotic cells.
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