huntingtons disease is carried on the dominant allele in a situation where two heterozygous parents have the disease what percentage of their offsprin
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HESI A2

HESI A2 Biology 2024

1. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

2. What is the role of tRNA during protein synthesis?

Correct answer: A

Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.

3. Which is a byproduct of fermentation in muscle cells?

Correct answer: C

Rationale: Lactic acid is a byproduct of fermentation in muscle cells. During intense exercise or when oxygen is limited, muscle cells use anaerobic respiration to generate energy. This process breaks down glucose into lactic acid, which can cause muscle fatigue and soreness. Choice A, Ethanol, is not produced in muscle cells during fermentation. Choice B, Pyruvic acid, is an intermediate product in glucose metabolism but is not a byproduct of fermentation in muscle cells. Choice D, Oxygen, is not a byproduct of fermentation but a reactant in aerobic respiration.

4. Three students measured the mass of a product of combustion. They recorded measurements of 14 g, 16 g, and 17 g. If the known mass of the product is 30 g, how would you describe the students’ measurements?

Correct answer: B

Rationale: The students' measurements are precise because they are consistently close to each other. However, they are not accurate because all the measurements deviate from the known mass of the product (30 g). Accuracy refers to how close a measurement is to the true or accepted value, while precision refers to the level of agreement among repeated measurements. Since the students' measurements are consistent but do not align with the true value, they can be considered precise but not accurate. Choice A is incorrect because accuracy relates to the proximity of the measurements to the true value, which is not the case here. Choice C is incorrect because although the measurements are precise, they are not accurate. Choice D is incorrect because the measurements are precise as they show good agreement with each other, even though they are not accurate.

5. Which organelle is found in protists but not in monerans?

Correct answer: A

Rationale: The Golgi apparatus is the correct answer. The Golgi apparatus is a cellular organelle responsible for processing and packaging proteins before they are transported to their final destination. Protists, being eukaryotic organisms, have membrane-bound organelles including the Golgi apparatus, which are absent in monerans. Monerans are prokaryotic organisms that lack membrane-bound structures such as the Golgi apparatus. Choices B, C, and D are incorrect as chromosomes, cytoplasm, and cell membranes are present in both protists and monerans.

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