HESI A2
HESI A2 Biology Practice Test 2024
1. Which organelle is involved in the synthesis of proteins?
- A. Endoplasmic Reticulum
- B. Ribosomes
- C. Lysosomes
- D. Vacuoles
Correct answer: B
Rationale: Ribosomes are the organelles involved in the synthesis of proteins. They are the cellular machinery responsible for translating mRNA into proteins, making them essential for cell function and structure. The other organelles listed, such as the Endoplasmic Reticulum, Lysosomes, and Vacuoles, have different functions unrelated to protein synthesis. The Endoplasmic Reticulum plays a role in protein processing and transport, Lysosomes are involved in digestion and waste removal, and Vacuoles are responsible for storage and maintaining cell turgor pressure.
2. Which statement is untrue?
- A. RNA is single-stranded.
- B. RNA contains uracil.
- C. DNA codes for proteins.
- D. DNA cannot be altered.
Correct answer: D
Rationale: DNA can be altered through various processes such as mutations, genetic engineering, and epigenetic modifications. Changes in DNA can occur naturally or through external influences, leading to variations in the genetic code. Therefore, the statement that DNA cannot be altered is untrue. Choices A, B, and C are true statements. RNA is indeed single-stranded, RNA contains uracil instead of thymine, and DNA serves as a template for protein synthesis.
3. The apical side of an epithelial cell:
- A. Is exposed to fluid or air
- B. Is on the bottom side of the cell
- C. Does not allow any substances to pass through
- D. None of the above
Correct answer: A
Rationale: The apical side of an epithelial cell is the top side, which is typically exposed to fluids, air, or the inside of an organ. This side allows substances to pass through it, facilitating the absorption, secretion, or excretion of various substances. Choice B is incorrect as the apical side is not on the bottom but the top side. Choice C is incorrect as the apical side does allow substances to pass through. Choice D is incorrect as there are characteristics associated with the apical side.
4. What is the most important component of the cell, contributing to protection, communication, and the passage of substances?
- A. Cytoplasm
- B. Cell Membrane
- C. Cytoskeleton
- D. Vacuole
Correct answer: B
Rationale: The cell membrane is the correct answer. It is the most important component of the cell as it provides protection, facilitates communication, and regulates the passage of substances in and out of the cell. The cytoplasm (Choice A) is the gel-like substance within the cell that holds organelles, but it is not primarily responsible for the functions mentioned in the question. The cytoskeleton (Choice C) provides structural support to the cell but is not directly involved in protection, communication, or substance passage. Vacuoles (Choice D) are responsible for storage and maintaining turgor pressure but do not play a primary role in the functions specified in the question.
5. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
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