HESI A2
Biology HESI A2 2024
1. A cell is in a solution in which the concentration of solutes is higher inside the cell than outside the cell. What would you expect to happen to the cell?
- A. It will swell and possibly burst.
- B. It will shrivel and shrink.
- C. It will maintain its current size.
- D. It will grow a supportive cell wall.
Correct answer: A
Rationale: When a cell is in a solution where the concentration of solutes is higher inside the cell than outside, it is in a hypertonic environment. In this situation, water will move into the cell in an attempt to equalize the concentration of solutes on both sides of the cell membrane through the process of osmosis. As a result, the cell will swell as it takes in more water, potentially leading to bursting or cell lysis. Choice B is incorrect because a cell in a hypertonic solution will not shrivel and shrink due to water moving into the cell. Choice C is incorrect because the cell will not maintain its current size; it will swell. Choice D is incorrect because growing a supportive cell wall is not the immediate response to being in a hypertonic environment.
2. Which of the following cell types has no nucleus?
- A. platelet
- B. red blood cell
- C. white blood cell
- D. phagocyte
Correct answer: B
Rationale: The correct answer is B, red blood cell. In humans, red blood cells do not have a nucleus. This unique feature allows them to have more space to carry oxygen efficiently. Platelets (choice A), white blood cells (choice C), and phagocytes (choice D) all have nuclei. Platelets are cell fragments, while white blood cells and phagocytes are types of immune cells that contain a nucleus for DNA and cellular functions.
3. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
4. If both parents have polydactylism, what percentage of their offspring is predicted to manifest the anomaly?
- A. 25%
- B. 50%
- C. 75%
- D. 100%
Correct answer: B
Rationale: When both parents have polydactylism, they each possess at least one dominant allele for polydactylism. Through a Punnett square analysis, it can be determined that 50% of their offspring will inherit the dominant allele from both parents. This results in a 100% chance of manifesting the anomaly (2 out of 4 possibilities). Therefore, 50% of the offspring are predicted to manifest the anomaly. Choices A, C, and D are incorrect as they do not align with the principles of Mendelian genetics and Punnett square analysis.
5. Cells reproduce by different processes, all of which fall into what two categories?
- A. Sexual reproduction and binary fission
- B. Sexual reproduction and asexual reproduction
- C. Asexual reproduction and binary fission
- D. Asexual reproduction and mitosis
Correct answer: B
Rationale: Cells reproduce through two main processes: 'sexual reproduction and asexual reproduction.' Sexual reproduction involves the fusion of gametes to produce offspring with genetic variation, while asexual reproduction involves the production of offspring genetically identical to the parent. Choice A is incorrect because binary fission is a form of asexual reproduction, not sexual reproduction. Choice C is incorrect because it combines two forms of asexual reproduction. Choice D is incorrect because mitosis is a specific type of cell division, not a form of reproduction involving the production of offspring.
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