HESI A2
Biology HESI A2 2024
1. A cell is in a solution in which the concentration of solutes is higher inside the cell than outside the cell. What would you expect to happen to the cell?
- A. It will swell and possibly burst.
- B. It will shrivel and shrink.
- C. It will maintain its current size.
- D. It will grow a supportive cell wall.
Correct answer: A
Rationale: When a cell is in a solution where the concentration of solutes is higher inside the cell than outside, it is in a hypertonic environment. In this situation, water will move into the cell in an attempt to equalize the concentration of solutes on both sides of the cell membrane through the process of osmosis. As a result, the cell will swell as it takes in more water, potentially leading to bursting or cell lysis. Choice B is incorrect because a cell in a hypertonic solution will not shrivel and shrink due to water moving into the cell. Choice C is incorrect because the cell will not maintain its current size; it will swell. Choice D is incorrect because growing a supportive cell wall is not the immediate response to being in a hypertonic environment.
2. Which statement is true of enzymes?
- A. They are made from lipids.
- B. They are made from proteins.
- C. They form double chains of DNA.
- D. They bind with catalysts.
Correct answer: B
Rationale: The correct answer is B: Enzymes are made from proteins. Enzymes are biological molecules that act as catalysts to speed up chemical reactions in living organisms. While the majority of enzymes are proteins, a few are made from RNA. The statement that enzymes are made from lipids (choice A) is incorrect. Enzymes do not form double chains of DNA (choice C) as their primary function is not related to DNA structure. Additionally, enzymes themselves do not bind with catalysts (choice D); instead, they act as catalysts to facilitate reactions.
3. What process involves the movement of water molecules through a selectively permeable membrane?
- A. Diffusion
- B. Osmosis
- C. Active Transport
- D. Facilitated Diffusion
Correct answer: B
Rationale: Osmosis is the process specifically involving the movement of water molecules through a selectively permeable membrane, from an area of higher water concentration to an area of lower water concentration. This process helps balance concentrations on both sides of the membrane. Choice A, Diffusion, refers to the movement of particles from an area of higher concentration to an area of lower concentration, not specific to water. Choice C, Active Transport, requires energy to move substances against their concentration gradient, unlike osmosis. Choice D, Facilitated Diffusion, involves the use of transport proteins to move specific substances across membranes, not limited to water molecules.
4. A scientist needs 12 mL of a solution. They have a bottle with 12L in it. Do they have enough?
- A. Yes, they have exactly what they need
- B. Yes, they have more than what they need
- C. No, they do not have enough
- D. None of the above
Correct answer: B
Rationale: 1 liter has 1000 milliliters. To convert from milliliters to liters, the decimal point moves three places to the left. So, the bottle has 12000 mL of solution, which is a lot more than the required 12 mL. Therefore, the scientist has more than what they need. Choice A is incorrect as the bottle has more than the required amount. Choice C is incorrect as the bottle contains significantly more solution than needed. Choice D is incorrect as the scientist does have more than enough solution.
5. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
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