HESI A2
Biology HESI A2 Practice Test
1. Which part of cellular respiration produces the greatest amount of ATP?
- A. electron transport chain
- B. glycolysis
- C. citric acid cycle
- D. fermentation
Correct answer: A
Rationale: The electron transport chain (ETC) produces the greatest amount of ATP during cellular respiration. This process occurs in the inner mitochondrial membrane and involves the transfer of electrons through a series of protein complexes, creating a proton gradient that drives the synthesis of ATP. By utilizing the energy from the electron carriers NADH and FADH2 produced in earlier stages of cellular respiration, the ETC can generate a large amount of ATP efficiently through oxidative phosphorylation. Glycolysis only produces a small amount of ATP in comparison to the ETC. The citric acid cycle generates some ATP but not as much as the ETC. Fermentation does not produce ATP through oxidative phosphorylation and yields a much smaller amount of ATP compared to the ETC.
2. Which of these molecules contains glucose?
- A. Proteins
- B. Lipids
- C. Nucleic acids
- D. Carbohydrates
Correct answer: D
Rationale: Glucose is a type of simple sugar and is classified as a carbohydrate. It is commonly found in various carbohydrate-containing foods such as fruits, vegetables, grains, and sugary snacks. Therefore, the molecule containing glucose would be a carbohydrate, making choice D the correct answer. Proteins (choice A) are made up of amino acids, lipids (choice B) are fats, and nucleic acids (choice C) are DNA and RNA, none of which contain glucose.
3. Which of the following is not true about antibiotics?
- A. They can interfere with the bacteria's ability to survive
- B. They can affect how bacteria multiply
- C. They can cause more bacteria to grow
- D. They only work on bacteria
Correct answer: C
Rationale: The correct answer is C. Antibiotics do not cause more bacteria to grow. They work by interfering with the bacteria's ability to survive, affecting how they multiply, or killing the bacteria cells. Antibiotics specifically target bacteria, so they do not promote the growth of more bacteria. Choices A, B, and D are true statements about antibiotics as they accurately describe how antibiotics work and their specific action on bacteria.
4. In an example of a male with hemophilia and a female carrier, what ratio of the offspring are predicted neither to carry nor to manifest the disease?
- A. 0 females : 1 male
- B. 1 female : 1 male
- C. 1 female : 0 males
- D. 2 females : 1 male
Correct answer: D
Rationale: In this scenario, the male offspring will inherit the Y chromosome from the father and the X chromosome from the carrier mother. As a result, they will not have the hemophilia gene. The female offspring will inherit one X chromosome from the mother, which does not carry the hemophilia gene, and one X chromosome from the father, which does not exist due to the Y chromosome. Therefore, all female offspring will not carry or manifest hemophilia, resulting in a ratio of 2 females to 1 male. Choice A is incorrect because it does not account for the female offspring. Choices B and C are incorrect as they do not reflect the correct ratio based on the inheritance pattern of hemophilia.
5. Which molecules contain only carbon, hydrogen, and oxygen?
- A. Lipids and proteins
- B. Carbohydrates and lipids
- C. Proteins and carbohydrates
- D. Nucleic acids and proteins
Correct answer: B
Rationale: Carbohydrates and lipids are the molecules that contain only carbon, hydrogen, and oxygen. Carbohydrates such as sugars and starches are made up of carbon, hydrogen, and oxygen in a ratio of 1:2:1, while lipids such as fats and oils are composed of carbon, hydrogen, and oxygen as well. Lipids typically contain more carbon and hydrogen atoms compared to oxygen atoms. Proteins contain nitrogen in addition to carbon, hydrogen, and oxygen, while nucleic acids contain phosphorus in addition to carbon, hydrogen, and oxygen. Therefore, choices A, C, and D are incorrect as they include molecules that contain elements other than carbon, hydrogen, and oxygen.
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