which organelle is responsible for making proteins

HESI A2

Biology HESI A2 Practice Test

1. Which organelle is responsible for making proteins?

A. Ribosome
B. Chloroplast
C. Lysosome
D. Mitochondrion

Correct answer: A

Rationale: Ribosomes are the organelles responsible for protein synthesis within the cell. They are the sites where amino acids are linked together to form proteins based on the instructions carried by mRNA (messenger RNA). Ribosomes can be found free-floating in the cytoplasm or attached to the endoplasmic reticulum, and they play a crucial role in translating genetic information into proteins. Chloroplasts are responsible for photosynthesis, lysosomes are involved in digestion and waste removal, and mitochondria are known as the powerhouse of the cell responsible for energy production through cellular respiration. Therefore, the ribosome is the correct organelle responsible for making proteins.

2. Which names a final step in protein synthesis?

A. DNA unzips.
B. Amino acids bond.
C. Transfer RNA bonds to messenger RNA.
D. Messenger RNA moves to ribosomes.

Correct answer: B

Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.

3. Which bacteria are spherical in shape?

A. Clostridia
B. Bacilli
C. Spirilla
D. Cocci

Correct answer: D

Rationale: The correct answer is D, Cocci. Bacteria that are spherical in shape are known as cocci. They can be found in various arrangements such as clusters, chains, or pairs. Examples of cocci bacteria include Staphylococcus aureus and Streptococcus pneumoniae. Choice A, Clostridia, consists of rod-shaped bacteria. Choice B, Bacilli, refers to rod-shaped bacteria as well. Choice C, Spirilla, are spiral-shaped bacteria, not spherical.

4. Select the option that best shows complementary base pairing in DNA:

A. A and G
B. A and C
C. A and A
D. A and T

Correct answer: D

Rationale: The correct answer is D. A purine (A) must pair with a pyrimidine (T) in DNA. This eliminates options A and C as they do not follow the rule of complementary base pairing. Adenine (A) always pairs with thymine (T) due to their specific shape and bonding properties in DNA structure. Choice B is incorrect because adenine does not pair with cytosine in DNA.

5. Which structure might be described as a core of nucleic acid surrounded by a protein coat?

A. RNA
B. Virus
C. Blue-green alga
D. Saprophyte

Correct answer: B

Rationale: A virus can be described as a core of nucleic acid (either RNA or DNA) surrounded by a protein coat, known as a capsid. This structure distinguishes viruses from other microorganisms such as blue-green algae (Cyanobacteria), fungi known as saprophytes, or individual RNA molecules. Viruses depend on a host cell to replicate and are considered non-living entities due to their inability to carry out metabolic functions independently.