HESI A2
Biology HESI A2 Practice Test
1. Which organelle is responsible for making proteins?
- A. Ribosome
- B. Chloroplast
- C. Lysosome
- D. Mitochondrion
Correct answer: A
Rationale: Ribosomes are the organelles responsible for protein synthesis within the cell. They are the sites where amino acids are linked together to form proteins based on the instructions carried by mRNA (messenger RNA). Ribosomes can be found free-floating in the cytoplasm or attached to the endoplasmic reticulum, and they play a crucial role in translating genetic information into proteins. Chloroplasts are responsible for photosynthesis, lysosomes are involved in digestion and waste removal, and mitochondria are known as the powerhouse of the cell responsible for energy production through cellular respiration. Therefore, the ribosome is the correct organelle responsible for making proteins.
2. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
3. What propels the cell forward?
- A. Microfilaments
- B. Propulsion
- C. Cilia
- D. Flagella
Correct answer: B
Rationale: Propulsion, not microfilaments, cilia, or flagella, is what drives the cell forward. Propulsion is the force or process that propels the cell forward and allows it to move within its environment. Microfilaments are involved in cell structure, cilia are small hair-like structures for movement, and flagella are tail-like structures used for cell propulsion in some organisms.
4. Which is true of gametes?
- A. They are diploid cells
- B. They are haploid cells
- C. They are somatic
- D. A & C are true
Correct answer: B
Rationale: Gametes are sex cells (sperm and eggs) that are involved in sexual reproduction. They are haploid cells, meaning they have half the number of chromosomes (n) compared to diploid cells. This is necessary for the formation of a diploid zygote when two gametes unite during fertilization. Somatic cells are non-reproductive cells in the body, so they are not gametes. Choice A is incorrect because gametes are not diploid but haploid. Choice C is incorrect because gametes are not somatic cells.
5. Epithelial cells are:
- A. Polarized
- B. Neutral
- C. Larger than other cells
- D. None of the above
Correct answer: A
Rationale: Epithelial cells have a distinct top (apical) and bottom (basal) side, demonstrating polarity. This polarity is essential for their specialized functions, such as secretion, absorption, and barrier formation. Choice B, 'Neutral,' is incorrect as epithelial cells exhibit polarity. Choice C, 'Larger than other cells,' is incorrect as epithelial cells come in various sizes and are not specifically larger than other cell types. Choice D, 'None of the above,' is incorrect as epithelial cells are indeed polarized.
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