HESI A2
Biology HESI A2 Practice Test
1. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
2. What cycle is the sequence of reactions by which most living cells generate energy during aerobic respiration?
- A. Calvin Cycle
- B. Krebs Cycle
- C. Photosynthesis
- D. Fermentation
Correct answer: B
Rationale: The Krebs Cycle is the correct answer. It is a series of reactions occurring in the mitochondria and is a crucial part of aerobic respiration. The Calvin Cycle is a part of photosynthesis, not respiration, making choice A incorrect. Photosynthesis (choice C) is the process by which plants, algae, and some bacteria convert light energy into chemical energy. Fermentation (choice D) is an anaerobic process that does not require oxygen and is not the primary energy-generating pathway during aerobic respiration, so it is incorrect.
3. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
4. What type of tissue is fat?
- A. Connective
- B. Muscle
- C. Nervous
- D. Epithelial
Correct answer: A
Rationale: Fat is a type of loose connective tissue known as adipose tissue. Adipose tissue primarily functions to store energy and provide cushioning and insulation for organs. While muscle tissue is responsible for movement, nervous tissue transmits nerve impulses, and epithelial tissue covers and protects body surfaces, fat specifically falls under the category of connective tissue.
5. What molecule is primarily responsible for providing energy to the cell?
- A. ATP
- B. DNA
- C. ADP
- D. Glycogen
Correct answer: A
Rationale: Correct! ATP (Adenosine Triphosphate) is the main molecule that stores and provides energy for cellular activities. ATP is known as the energy currency of the cell, where energy released from the breakdown of nutrients is stored in the high-energy phosphate bonds of ATP. Choices B, C, and D are incorrect because DNA carries genetic information, ADP is the precursor of ATP, and glycogen is a polysaccharide used for energy storage, not direct energy provision.
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