HESI A2
Biology HESI A2 Practice Exam
1. Which is not part of a nucleic acid?
- A. Sulfate
- B. Phosphate
- C. Carbon
- D. Nitrogen
Correct answer: A
Rationale: Sulfate is not part of a nucleic acid. Nucleic acids, such as DNA and RNA, are composed of nucleotide units, which consist of a phosphate group, a sugar molecule (ribose in RNA and deoxyribose in DNA), and a nitrogenous base. Carbon and nitrogen are essential elements found in nucleic acids, while sulfate is not a component of nucleic acid structure. Therefore, the correct answer is A: Sulfate.
2. Which system maintains the body's balance through the release of hormones directly into the bloodstream?
- A. The gastrointestinal system
- B. The endocrine system
- C. The digestive system
- D. The endocrine system
Correct answer: D
Rationale: The correct answer is D: The endocrine system. The endocrine system maintains the body's balance through the release of hormones directly into the bloodstream. Hormones produced by glands in the endocrine system regulate various bodily functions such as metabolism, growth, and reproduction. This system plays a crucial role in maintaining homeostasis by releasing hormones that help control and coordinate different processes in the body. Choices A, C, and B are incorrect. The gastrointestinal system is responsible for digestion, absorption of nutrients, and excretion of waste; the digestive system includes the gastrointestinal system and other accessory organs; and choice B is a duplicate of the correct answer.
3. Within the biological hierarchical system of organization, which of the following is least inclusive?
- A. phylum
- B. order
- C. kingdom
- D. species
Correct answer: D
Rationale: The correct answer is 'D: species.' In the biological hierarchical system of organization, a species is the least inclusive level. A species consists of organisms that share similar characteristics and can interbreed to produce fertile offspring. On the other hand, a phylum, order, and kingdom are more inclusive classifications that encompass multiple species. Phylum groups together related classes, order groups together related families, and kingdom groups together related phyla. Therefore, species is the least inclusive category within the biological hierarchical system.
4. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.
5. What is the initial step in the metabolism of food to cellular energy?
- A. Citric Acid Cycle
- B. Glycolysis
- C. Electron Transport Chain
- D. Photosynthesis
Correct answer: B
Rationale: The correct answer is B: Glycolysis. Glycolysis is the initial step in the metabolism of food to cellular energy. During glycolysis, glucose is broken down into pyruvate, generating ATP and NADH. Choices A, C, and D are incorrect because the Citric Acid Cycle and Electron Transport Chain occur later in cellular respiration, while Photosynthesis is the process by which plants convert light energy into chemical energy.
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