HESI A2
Biology HESI A2 Practice Exam
1. Which cells in the human body lack nuclei?
- A. Nerve cells
- B. Red blood cells
- C. Liver cells
- D. Connective tissue cells
Correct answer: B
Rationale: Red blood cells, also known as erythrocytes, lack nuclei in humans. This absence of a nucleus allows more space for hemoglobin, the protein responsible for carrying oxygen, making red blood cells efficient at their function of oxygen transport in the body. Nerve cells (Choice A), liver cells (Choice C), and connective tissue cells (Choice D) all possess nuclei as they require genetic material for their functions, such as cell signaling, protein synthesis, and structural support.
2. The procedure to focus an image using a compound microscope involves
- A. Adjusting the coarse adjustment each time a new magnification is selected
- B. Adjusting the fine adjustment each time a new magnification is selected
- C. Adjusting the stage each time a new magnification is selected
- D. All of the above
Correct answer: B
Rationale: When using a compound microscope, it is essential to adjust the fine adjustment knob each time you switch to a new magnification level. The fine adjustment knob allows for precise focusing on the specimen at different magnifications, ensuring a clear and sharp image. The coarse adjustment knob is typically used only at the lower magnification settings to bring the image into view roughly. Adjusting the stage may be necessary based on the size and thickness of the specimen, but it does not need to be done every time a new magnification is selected. Therefore, option B is the correct choice as it focuses on the key aspect of precise focusing during magnification changes.
3. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?
- A. Nucleus
- B. Cell membrane
- C. Endoplasmic reticulum
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.
4. Physical factors such as temperature and pH can alter enzyme activity because they have an effect on the enzyme's ___________.
- A. acidity
- B. shape
- C. chemistry
- D. substrate
Correct answer: B
Rationale: Physical factors such as temperature and pH can alter enzyme activity by affecting the enzyme's shape. Enzymes rely on their specific shapes to function properly and catalyze reactions. Any changes in temperature or pH can disrupt these shapes, causing the enzyme to become denatured and lose its functionality. Therefore, alterations in temperature and pH can impact enzyme activity by directly affecting their shapes. Choices A, C, and D are incorrect because while pH can affect acidity and chemical properties of the enzyme, and temperature can influence the enzyme-substrate interaction, the primary reason for enzyme activity alteration due to temperature and pH is the change in the enzyme's shape.
5. What organelle pushes water out of the cell?
- A. Lysosomes
- B. Vacuoles (contractile)
- C. Mitochondria
- D. Nucleus
Correct answer: B
Rationale: The correct answer is B: Vacuoles (contractile). Vacuoles (contractile) are responsible for expelling excess water out of the cell. Lysosomes are involved in the digestion and removal of waste materials, mitochondria are the powerhouse of the cell involved in energy production, and the nucleus contains the cell's genetic material but does not play a role in pushing water out of the cell.
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