HESI A2
HESI A2 Practice Test Anatomy and Physiology
1. Which bone does not articulate with any other bone?
- A. Femur
- B. Hyoid
- C. Radius
- D. Scapula
Correct answer: B
Rationale: The hyoid bone is the correct answer as it is the only bone in the human body that does not articulate with any other bone. Instead, it is suspended in the neck by ligaments and muscles, providing support for the tongue and serving as an attachment point for various throat and tongue muscles. The femur (Choice A), radius (Choice C), and scapula (Choice D) all articulate with other bones in the body at various joints, making them incorrect answers for this question.
2. Which hormone is responsible for regulating the sleep-wake cycle?
- A. Melatonin
- B. Thyroxine
- C. Insulin
- D. Cortisol
Correct answer: A
Rationale: Melatonin, produced by the pineal gland, regulates the sleep-wake cycle by responding to light and darkness in the environment. It plays a crucial role in signaling the body when it's time to sleep and wake up, helping to establish and maintain a healthy circadian rhythm. Thyroxine, Insulin, and Cortisol do not directly regulate the sleep-wake cycle, making them incorrect choices for this question.
3. What does trypsin break down in the body?
- A. Fat
- B. Starch
- C. Proteins
- D. Nucleic acids
Correct answer: C
Rationale: Trypsin is an enzyme that specifically breaks down proteins into smaller peptides by hydrolyzing peptide bonds. It is a key enzyme involved in the digestion of proteins in the body, particularly in the small intestine where it helps in the final stages of protein digestion. Choices A, B, and D are incorrect because trypsin does not break down fats, starch, or nucleic acids; its primary function is the digestion of proteins.
4. What is the main function of the large intestine?
- A. Absorption of nutrients
- B. Absorption of water
- C. Secretion of digestive enzymes
- D. Breaking down fats
Correct answer: B
Rationale: The main function of the large intestine is the absorption of water and electrolytes from indigestible food residues, helping to form solid waste (feces) for elimination. It mainly reabsorbs water and compacts the remaining material into feces, playing a crucial role in maintaining fluid balance in the body. Choices A, C, and D are incorrect because absorption of nutrients primarily occurs in the small intestine, secretion of digestive enzymes mainly occurs in the stomach and small intestine, and breaking down fats primarily occurs in the small intestine with the help of bile from the liver and enzymes.
5. Which of the following epithelial types is correctly matched with its major function?
- A. Simple squamous epithelium – diffusion
- B. Stratified squamous epithelium – protection
- C. Stratified squamous epithelium – diffusion
- D. Simple columnar epithelium – secretion or absorption
Correct answer: D
Rationale: The correct answer is D. Simple columnar epithelium is indeed primarily responsible for secretion and absorption due to its tall shape and presence of microvilli, which increase surface area for these functions. Simple squamous epithelium is mainly involved in diffusion, allowing for the exchange of gases or nutrients. Stratified squamous epithelium functions more for protection against mechanical stress and pathogens, as it forms a tough, protective barrier due to its many layers.
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