HESI A2
HESI A2 Anatomy and Physiology Practice Exam
1. When are gallstones most problematic?
- A. When they block a duct
- B. When they contain cholesterol
- C. When they contain bilirubin
- D. When they begin to dissolve
Correct answer: A
Rationale: Gallstones become most problematic when they block a duct, such as the bile duct or cystic duct. This blockage can lead to various complications, including inflammation, infection, and even damage to the gallbladder or liver. In severe cases, a blocked duct can cause intense pain, jaundice, and other serious symptoms that require medical intervention. Choices B, C, and D are incorrect because the presence of cholesterol or bilirubin in gallstones or the process of dissolution do not necessarily indicate when gallstones become most problematic. The critical issue arises when the stones obstruct a duct, leading to complications.
2. What is the function of the liver in digestion?
- A. To produce bile
- B. To store glucose
- C. To secrete digestive enzymes
- D. To detoxify harmful substances
Correct answer: A
Rationale: The liver's main role in digestion is to produce bile, a substance that aids in the breakdown and absorption of fats in the small intestine. Bile emulsifies fats, helping enzymes break them down into smaller molecules for easier absorption in the digestive tract. Therefore, the correct answer is A: 'To produce bile.' Storing glucose, secreting digestive enzymes, and detoxifying harmful substances are functions of the liver, but they are not primarily related to digestion.
3. Which organelle is responsible for generating energy within a cell?
- A. Nucleus
- B. Ribosome
- C. Mitochondria
- D. Golgi apparatus
Correct answer: C
Rationale: Mitochondria are commonly referred to as the powerhouses of the cell as they are primarily responsible for generating energy through cellular respiration. This process involves converting nutrients into adenosine triphosphate (ATP), which is the main energy currency of the cell. The nucleus is responsible for storing the cell's genetic material, the ribosome is involved in protein synthesis, and the Golgi apparatus is responsible for packaging and distributing molecules produced by the cell; therefore, they are not directly involved in energy generation.
4. Which hormone is produced by the thyroid gland?
- A. Insulin
- B. Thyroxine
- C. Glucagon
- D. Cortisol
Correct answer: B
Rationale: Thyroxine is the hormone produced by the thyroid gland. It plays a crucial role in regulating metabolism, heart rate, and growth. Insulin is produced by the pancreas to regulate blood sugar levels, not by the thyroid gland. Glucagon is also produced by the pancreas and helps increase blood sugar levels. Cortisol is produced by the adrenal glands and is involved in stress response and metabolism, not by the thyroid gland.
5. Which of the following is the largest organ in the human body?
- A. Liver
- B. Skin
- C. Brain
- D. Heart
Correct answer: B
Rationale: The skin is the largest organ in the human body. It serves as a protective barrier against the environment, regulates temperature, and provides sensory information. The liver, brain, and heart are vital organs, but they are not as extensive as the skin. The liver is primarily responsible for detoxification and metabolism. The brain is the control center of the body, coordinating various functions. The heart is a crucial organ that pumps blood throughout the body. However, in terms of size, the skin surpasses all of these organs.
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