HESI A2
HESI A2 Anatomy and Physiology Practice Exam
1. When are gallstones most problematic?
- A. When they block a duct
- B. When they contain cholesterol
- C. When they contain bilirubin
- D. When they begin to dissolve
Correct answer: A
Rationale: Gallstones become most problematic when they block a duct, such as the bile duct or cystic duct. This blockage can lead to various complications, including inflammation, infection, and even damage to the gallbladder or liver. In severe cases, a blocked duct can cause intense pain, jaundice, and other serious symptoms that require medical intervention. Choices B, C, and D are incorrect because the presence of cholesterol or bilirubin in gallstones or the process of dissolution do not necessarily indicate when gallstones become most problematic. The critical issue arises when the stones obstruct a duct, leading to complications.
2. Which hormone is not produced by the pituitary gland?
- A. FSH
- B. TRH
- C. LH
- D. ADH
Correct answer: B
Rationale: Thyrotropin-releasing hormone (TRH) is not produced by the pituitary gland. TRH is actually produced by the hypothalamus and acts on the pituitary gland to stimulate the release of thyroid-stimulating hormone (TSH). On the other hand, FSH (follicle-stimulating hormone), LH (luteinizing hormone), and ADH (antidiuretic hormone) are all hormones directly produced by the pituitary gland.
3. Which hormone is involved in the body's stress response?
- A. Insulin
- B. Adrenaline
- C. Cortisol
- D. Melatonin
Correct answer: C
Rationale: The correct answer is C: Cortisol. Cortisol, produced by the adrenal glands, is involved in the body's stress response. It helps regulate metabolism, immune function, and the body's response to stressors by increasing blood sugar levels, suppressing the immune system, and aiding in the metabolism of fats, carbohydrates, and proteins. Choice A, Insulin, is a hormone that regulates blood sugar levels and is not primarily involved in the stress response. Choice B, Adrenaline, is also known as epinephrine and is involved in the fight-or-flight response, which is related to stress but is not the main hormone in the body's stress response. Choice D, Melatonin, is a hormone that regulates sleep-wake cycles and is not directly involved in the stress response.
4. Where are B-lymphocytes produced?
- A. Thymus
- B. Red bone marrow
- C. Lymph nodes
- D. Spleen
Correct answer: B
Rationale: B-lymphocytes are produced in the red bone marrow. The red bone marrow is the primary site for B-cell development, where they mature before entering the circulation. The thymus is responsible for T-lymphocyte maturation, not B-lymphocytes. Lymph nodes and spleen play roles in immune responses but are not the primary sites for B-lymphocyte production.
5. Where is a gallstone most likely to cause pain?
- A. In the upper right quadrant of the abdomen
- B. In the lower right quadrant of the abdomen
- C. In the umbilical region
- D. Along the pelvic girdle
Correct answer: A
Rationale: A gallstone is most likely to cause pain in the upper right quadrant of the abdomen. This specific area corresponds to the location of the gallbladder. When a gallstone blocks the flow of bile from the gallbladder, it can lead to inflammation and pain in this region. The pain may also radiate to the back or right shoulder blade due to referred pain patterns associated with gallbladder issues. Choices B, C, and D are incorrect because gallstone pain is typically felt in the upper right quadrant of the abdomen, not the lower right quadrant, umbilical region, or along the pelvic girdle.
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