HESI A2
HESI A2 Practice Test Biology
1. What is the role of tRNA during protein synthesis?
- A. Carries amino acids to the ribosome
 - B. Links nucleotides together
 - C. Copies DNA sequences
 - D. Replicates genetic material
 
Correct answer: A
Rationale: During protein synthesis, tRNA plays the crucial role of carrying amino acids to the ribosome. This process ensures that the correct amino acids are brought to the ribosome according to the mRNA sequence. Choice B, linking nucleotides together, refers to the role of RNA polymerase in transcription, not tRNA. Choice C, copying DNA sequences, is the function of DNA polymerase during DNA replication, while choice D, replicating genetic material, is an overarching function of DNA replication, not specific to tRNA's role in protein synthesis.
2. What is the composition of the plasma membrane?
- A. Proteins
 - B. Lipids
 - C. Carbohydrates
 - D. Nucleotides
 
Correct answer: B
Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.
3. How should a researcher test the hypothesis that a particular species of bird vocalizes most in the hours around dawn?
- A. Observe a flock of the birds in captivity and record them at two-hour intervals from predawn until sunset for a month.
 - B. Observe a flock of the birds in the wild and record them at one-hour intervals from predawn until sunset in several seasons.
 - C. Observe a flock of the birds in the wild and record them in predawn and postdawn hours every day for six months.
 - D. Observe a flock of the birds in the wild, record them at one-hour intervals for a month, and compare that recording to recordings of other species.
 
Correct answer: C
Rationale: Observing a flock of the birds in the wild and recording them in predawn and postdawn hours every day for six months would be the best way to test the hypothesis that a particular species of bird vocalizes most in the hours around dawn. This method allows for consistent monitoring of the birds during specific times of interest over an extended period, providing a comprehensive dataset to accurately analyze the vocalization patterns. Options A and B do not focus specifically on dawn hours, making them less suitable for testing the hypothesis. Option D introduces a comparison with other species, which is unnecessary and distracts from the main objective of studying the vocalization pattern of the particular bird species around dawn.
4. Which of the following is not true about antibiotics?
- A. They can interfere with the bacteria's ability to survive
 - B. They can affect how bacteria multiply
 - C. They can cause more bacteria to grow
 - D. They only work on bacteria
 
Correct answer: C
Rationale: The correct answer is C. Antibiotics do not cause more bacteria to grow. They work by interfering with the bacteria's ability to survive, affecting how they multiply, or killing the bacteria cells. Antibiotics specifically target bacteria, so they do not promote the growth of more bacteria. Choices A, B, and D are true statements about antibiotics as they accurately describe how antibiotics work and their specific action on bacteria.
5. A cell that does not contain membrane-bound organelles or a defined nucleus would be classified as:
- A. eukaryotic
 - B. embryonic
 - C. prokaryotic
 - D. symbiotic
 
Correct answer: C
Rationale: A cell that does not contain membrane-bound organelles or a defined nucleus is classified as prokaryotic. Prokaryotic cells lack a true nucleus, and their genetic material is typically found in a region called the nucleoid. Examples of prokaryotic organisms include bacteria and archaea. Eukaryotic cells, on the other hand, contain membrane-bound organelles and a true nucleus, distinguishing them from prokaryotic cells. Embryonic and symbiotic classifications are not directly related to the presence of organelles or a nucleus in cells.
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