HESI A2
HESI A2 Biology 2024
1. What happens to messenger RNA when it reaches the cytoplasm?
- A. It attaches to a ribosome.
- B. It unzips, exposing nitrogen bases.
- C. It pairs with the DNA bases.
- D. It pulls free of the DNA strand.
Correct answer: A
Rationale: Messenger RNA (mRNA) carries genetic information from the DNA in the nucleus to the ribosomes in the cytoplasm. When mRNA reaches the cytoplasm, it attaches to a ribosome. The ribosome functions as the site for protein synthesis through translation, where the genetic code carried by mRNA is read and translated into a specific sequence of amino acids. Choices B, C, and D are incorrect because mRNA does not unzip, expose nitrogen bases, pair with DNA bases, or pull free of the DNA strand in the cytoplasm. The primary function of mRNA in the cytoplasm is to serve as a template for protein synthesis by binding to ribosomes.
2. What is the term for the movement of ions and other molecular substances across cell membranes without the need for energy?
- A. Active Transport
- B. Passive Transport
- C. Diffusion
- D. Osmosis
Correct answer: B
Rationale: Passive transport refers to the movement of substances across cell membranes without the need for energy input. In contrast, active transport, choice A, requires energy to move substances against their concentration gradient. Diffusion, choice C, is a type of passive transport where substances move from an area of high concentration to low concentration. Osmosis, choice D, specifically refers to the movement of water molecules across a selectively permeable membrane.
3. Which names a final step in protein synthesis?
- A. DNA unzips.
- B. Amino acids bond.
- C. Transfer RNA bonds to messenger RNA.
- D. Messenger RNA moves to ribosomes.
Correct answer: B
Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.
4. Which of the following is a protein?
- A. cellulose
- B. hemoglobin
- C. estrogen
- D. ATP
Correct answer: B
Rationale: The correct answer is 'hemoglobin' because it is a protein that carries oxygen in the blood. Cellulose is a carbohydrate found in the cell walls of plants, not a protein. Estrogen is a hormone, not a protein. ATP (adenosine triphosphate) is a molecule that carries energy within cells, not a protein.
5. Which organelle contains the genetic material of the cell?
- A. Golgi apparatus
- B. Ribosome
- C. Endoplasmic reticulum
- D. Nucleus
Correct answer: D
Rationale: The correct answer is 'D: Nucleus.' The nucleus is the organelle that contains the cell's genetic material, which is the DNA. The genetic material in the nucleus controls the cell's activities and plays a crucial role in inheritance. Choices A, B, and C are incorrect because the Golgi apparatus is involved in modifying, sorting, and packaging of proteins; ribosomes are involved in protein synthesis; and endoplasmic reticulum is involved in protein and lipid synthesis and transportation, but none of them contain the genetic material of the cell.
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