HESI A2
HESI A2 Biology Practice Test
1. Which type of passive transport uses proteins that change shape to move a target molecule through the membrane?
- A. Diffusion
- B. Carrier proteins
- C. Channel proteins
- D. None of the above
Correct answer: B
Rationale: The correct answer is B: Carrier proteins. Carrier proteins are involved in facilitated diffusion, a type of passive transport where specific target molecules are moved across the membrane with the help of proteins that change shape. These carrier proteins bind to the target molecule on one side of the membrane, undergo a conformational change, and then release the molecule on the other side. This process is crucial for the selective transport of certain molecules that cannot pass through the membrane by simple diffusion. Choices A and C are incorrect because diffusion and channel proteins do not involve proteins that change shape to transport target molecules selectively. Choice D is incorrect as carrier proteins fit the description provided in the question.
2. In a strand of DNA, you would expect to see adenine paired with ___________.
- A. cytosine
- B. uracil
- C. thymine
- D. guanine
Correct answer: C
Rationale: In a strand of DNA, adenine always pairs with thymine through two hydrogen bonds. This pairing is a fundamental aspect of DNA structure, where adenine and thymine complement each other in the double helix. Choice A (cytosine) is incorrect because adenine does not pair with cytosine in DNA. Choice B (uracil) is incorrect as uracil is found in RNA, not DNA. Choice D (guanine) is incorrect as guanine pairs with cytosine, not adenine, in DNA.
3. How does asexual reproduction differ from sexual reproduction?
- A. asexual reproduction results in all cells being identical to the original cell; sexual reproduction results in half of the cells being identical to the original cell
- B. asexual reproduction results in two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
- C. sexual reproduction involves two cells that contribute genetic material to daughter cells, resulting in significantly greater variation
- D. sexual reproduction involves one cell that yields all cells produced to be identical
Correct answer: C
Rationale: Sexual reproduction involves two cells (gametes) that contribute genetic material to daughter cells, resulting in significantly greater genetic variation in the offspring. This genetic variation is essential for evolution and adaptation to environmental changes. In contrast, asexual reproduction involves one cell dividing to produce offspring that are genetically identical to the parent cell. Choice A is incorrect because sexual reproduction does not result in half of the cells being identical to the original cell; it involves two cells contributing genetic material. Choice B is incorrect because asexual reproduction does not result in significantly greater variation; it produces genetically identical offspring. Choice D is incorrect because sexual reproduction involves two cells contributing genetic material, not one cell yielding all identical cells.
4. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
5. What are the two catabolic pathways that lead to cellular energy production?
- A. Fermentation and internal respiration
- B. Fermentation and external respiration
- C. Fermentation and cellular respiration
- D. Fermentation and anaerobic respiration
Correct answer: C
Rationale: The correct answer is 'Fermentation and cellular respiration.' Fermentation is an anaerobic catabolic process that occurs in the absence of oxygen, producing limited amounts of ATP. Cellular respiration, on the other hand, is the aerobic catabolic pathway that occurs in the presence of oxygen and is the most efficient way of producing ATP. Choices A, B, and D are incorrect because internal respiration, external respiration, and anaerobic respiration are not the correct pathways leading to cellular energy production.
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