HESI A2
Biology HESI A2 Practice Exam
1. RNA is made from DNA through a process called ___________.
- A. transcription
- B. synthesis
- C. translation
- D. replication
Correct answer: A
Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.
2. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
3. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
4. Which component is not found in the nucleotide of DNA?
- A. Simple sugar
- B. Nitrogen base
- C. Phosphate group
- D. Citric acid
Correct answer: D
Rationale: Citric acid is not found in the nucleotide of DNA. A DNA nucleotide is composed of a simple sugar (deoxyribose), a nitrogen base (adenine, thymine, cytosine, or guanine), and a phosphate group. Citric acid is not part of DNA nucleotides; instead, it is involved in the citric acid cycle of cellular respiration. Choices A, B, and C are essential components of DNA nucleotides, making them incorrect answers.
5. What is the classification of organisms into different categories based on their physical characteristics and presumed natural relationship?
- A. Biology
- B. Taxonomy
- C. Grouping
- D. Nomenclature
Correct answer: B
Rationale: Taxonomy is the correct answer. Taxonomy is the branch of biology that deals with the classification of organisms into different categories based on their physical characteristics and presumed natural relationship. It involves naming and categorizing organisms into hierarchical groups to show their evolutionary relationships. Choice A, 'Biology,' is incorrect as it is the broader field of science that encompasses the study of living organisms. Choice C, 'Grouping,' is incorrect as it is a general term that does not specifically refer to the systematic classification of organisms. Choice D, 'Nomenclature,' is incorrect as it refers to the system of naming organisms rather than the classification based on physical characteristics and natural relationships.
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