Nursing Elites

1. RNA is made from DNA through a process called ___________.

• A. transcription
• B. synthesis
• C. translation
• D. replication

Correct answer: A

Rationale: RNA is made from DNA through a process called transcription. During transcription, an enzyme called RNA polymerase reads the DNA template and synthesizes a complementary RNA molecule. This process is essential for gene expression and allows the information encoded in DNA to be converted into functional RNA molecules. Choice B, 'synthesis,' is incorrect as it is a general term and does not specifically describe the process of RNA formation from DNA. Choice C, 'translation,' is incorrect as it refers to the process where the mRNA is used to assemble amino acids during protein synthesis, not the conversion of DNA to RNA. Choice D, 'replication,' is incorrect as it is the process of making an identical copy of DNA, not converting DNA into RNA.

2. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

• A. 0%
• B. 25%
• C. 50%
• D. 100%

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

3. Which names a final step in protein synthesis?

• A. DNA unzips.
• B. Amino acids bond.
• C. Transfer RNA bonds to messenger RNA.
• D. Messenger RNA moves to ribosomes.

Correct answer: B

Rationale: The final step in protein synthesis is when amino acids bond together to form a protein chain. This process occurs during translation, where transfer RNA (tRNA) brings specific amino acids to the ribosome, and the ribosome catalyzes the formation of peptide bonds between the amino acids. This step ultimately leads to the synthesis of a complete protein based on the instructions from messenger RNA (mRNA). Choice A ('DNA unzips') is incorrect as it refers to the initiation of transcription, not the final step of protein synthesis. Choice C ('Transfer RNA bonds to messenger RNA') is incorrect as it describes the process of translation initiation rather than the final step. Choice D ('Messenger RNA moves to ribosomes') is also incorrect as mRNA is already present at the ribosomes throughout the translation process, not just in the final step.

4. Where is DNA stored?

• A. The nucleus
• B. Ribosomes
• C. Endoplasmic reticulum
• D. Mitochondria

Correct answer: A

Rationale: DNA is stored in the nucleus of a cell. The nucleus houses the cell's genetic material, including the DNA, which contains the instructions for building and operating the cell. The nucleus controls the activities of the cell and is essential for proper cell function and reproduction. Ribosomes are responsible for protein synthesis, not DNA storage. The endoplasmic reticulum is involved in protein and lipid synthesis, storage, and transport but does not store DNA. Mitochondria are known as the powerhouse of the cell, producing energy in the form of ATP, but they do not store DNA.

5. Tonicity refers to the movement of:

• A. Water
• B. Solute
• C. Cells
• D. None of the above

Correct answer: A

Rationale: Tonicity refers to the movement of water across a membrane in response to differences in solute concentration. In a hypertonic solution, where there is a higher concentration of solutes outside the cell, water will move out of the cell to try to reach equilibrium. In a hypotonic solution, where there is a lower concentration of solutes outside the cell, water will move into the cell to balance the concentrations. Cells and solutes themselves do not actively move in response to tonicity; it is the movement of water that helps achieve equilibrium. Therefore, the correct answer is water (Choice A). Choices B, C, and D are incorrect as tonicity specifically refers to water movement and not the movement of solutes, cells, or none of the above.

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