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HESI A2

Biology HESI A2 Practice Test

1. Which of the following is true of optical microscopy?

Correct answer: D

Rationale: The correct answer is D, 'More than one of the above is true.' Optical microscopy utilizes visible light (Choice B) and often involves the use of dyes for samples (Choice C). Using dyes helps enhance contrast, making it easier to visualize the structures being observed. Choice A is incorrect as optical microscopy does not utilize scanning electrons, but rather visible light.

2. Which of the following is true of the Krebs cycle?

Correct answer: B

Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.

3. What type of transport moves substances across the cell membrane using energy?

Correct answer: B

Rationale: The correct answer is B: Active Transport. Active transport moves substances across the cell membrane by utilizing energy from the cell, typically in the form of ATP. This process allows the cell to move molecules against their concentration gradient, requiring energy expenditure. Choices A, C, and D are incorrect because passive transport does not require energy input, facilitated diffusion involves the assistance of proteins but does not directly use energy, and osmosis is the diffusion of water molecules specifically, not substances, across a selectively permeable membrane.

4. Why doesn't an antibiotic work for treating the flu?

Correct answer: B

Rationale: The correct answer is B. Antibiotics are used to treat bacterial infections, not viral infections like the flu. The flu is caused by a virus, and antibiotics are ineffective against viruses. Choice A is incorrect because it does not address the fact that antibiotics do not work on viruses. Choice C is incorrect as the issue is not related to the dosage amount, but rather the nature of the infection. Choice D is incorrect as there is a specific reason why antibiotics do not work for the flu.

5. In contrast with triglycerides, phospholipids are lacking one of which of the following components?

Correct answer: B

Rationale: Phospholipids are structurally similar to triglycerides but lack one of the fatty acid chains that triglycerides possess. Triglycerides consist of three fatty acid chains attached to a glycerol molecule, while phospholipids have two fatty acid chains and a phosphate group attached to a glycerol backbone. Therefore, phospholipids are lacking the third fatty acid chain found in triglycerides. Choice A (Monosaccharide) is incorrect because neither triglycerides nor phospholipids contain monosaccharides in their structure. Choice C (Phosphates) is incorrect because phospholipids actually contain phosphates, unlike triglycerides. Choice D (Fatty acid) is incorrect as both triglycerides and phospholipids contain fatty acids, but the number of fatty acid chains differs between the two.

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