HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. What is the purpose of the mitochondria?
- A. Control the cell
- B. Create energy
- C. Create proteins
- D. Package waste for removal
Correct answer: B
Rationale: The correct answer is B: Create energy. The primary purpose of the mitochondria is to generate energy for the cell. Mitochondria are known as the 'powerhouses' of the cell because they produce ATP (adenosine triphosphate), which is the energy currency used by cells to carry out various functions and processes. Choice A is incorrect as the mitochondria do not control the cell but rather produce energy. Choice C is incorrect as protein synthesis primarily occurs in the ribosomes. Choice D is incorrect as packaging waste for removal is a function associated with lysosomes, not mitochondria.
3. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
4. Why is DNA important for metabolic activities of the cell?
- A. It controls the synthesis of enzymes.
- B. It stabilizes the cell wall.
- C. It initiates cell division.
- D. It prevents diffusion of nutrients.
Correct answer: A
Rationale: The correct answer is A. DNA plays a crucial role in metabolic activities by controlling the synthesis of enzymes. Enzymes are the biological catalysts that regulate and facilitate metabolic reactions within the cell. Choice B is incorrect because DNA is not involved in stabilizing the cell wall; that role is usually associated with other components like the cell membrane. Choice C is incorrect as cell division is primarily regulated by different processes and molecules, not directly by DNA. Choice D is incorrect because DNA is not related to preventing the diffusion of nutrients; instead, it is involved in coding for proteins that aid in various cellular functions.
5. Which type of sugar is a disaccharide?
- A. Sucrose
- B. Fructose
- C. Glucose
- D. Galactose
Correct answer: A
Rationale: The correct answer is A, Sucrose. Sucrose is a disaccharide composed of one molecule of glucose and one molecule of fructose. When glucose and fructose combine, they form sucrose. Choice B, Fructose, is a monosaccharide, not a disaccharide. Choice C, Glucose, is also a monosaccharide, not a disaccharide. Choice D, Galactose, is another monosaccharide and not a disaccharide.
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