imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. Which of the following animals would have the least energy efficiency in nutrient consumption?

Correct answer: A

Rationale: Cows are ruminant animals that have multiple stomachs and require large amounts of food to digest and convert into energy. They have lower energy efficiency compared to insects like caterpillars, coyotes, and crickets, which have more efficient nutrient consumption processes. The digestive system and metabolic functions of cows result in them having the least energy efficiency in nutrient consumption among the given choices. Caterpillars, coyotes, and crickets have more efficient nutrient consumption processes, making them more energy-efficient than cows.

3. Which, if any, of the following statements are true?

Correct answer: D

Rationale: Both statements A and C are true. Water indeed boils at approximately 100°C (212°F) at standard atmospheric pressure. However, water boils at a lower temperature in areas of lower pressure due to the decreased atmospheric pressure, which affects the vapor pressure and boiling point of water. Statement B is incorrect because the boiling point is the temperature at which the vapor pressure equals the external pressure (atmospheric pressure in this case), not when it is higher.

4. Which of the following shows how information is transformed to make a protein?

Correct answer: A

Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.

5. Where is the genetic code for each person stored?

Correct answer: B

Rationale: The genetic code for each person is stored in DNA. DNA carries all the hereditary information, including unique traits and characteristics. RNA (Choice A) is involved in protein synthesis but does not hold the complete genetic code. The nucleus (Choice C) is a cellular organelle that houses the DNA, but it is not the genetic code itself. Chromosomes (Choice D) are structures made of DNA and proteins, but the genetic code is specifically encoded in the DNA molecule.

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