imagine that two parents both carry the recessive gene for cystic fibrosis any homozygous recessive offspring will manifest the disease what percentag
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HESI A2

Biology HESI A2 2024

1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?

Correct answer: B

Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.

2. When the genotype consists of a dominant and a recessive allele, the phenotype will be like the _ allele.

Correct answer: A

Rationale: When the genotype consists of a dominant and a recessive allele, the phenotype will be like the dominant allele. This is because dominant alleles typically mask the expression of recessive alleles. Therefore, the dominant allele will be expressed in the phenotype in most basic cases. The recessive allele will only be expressed phenotypically if the individual is homozygous recessive. Choice B, 'Recessive,' is incorrect because the phenotype will not be like the recessive allele in this case. Choice C, 'Both,' is incorrect because in simple dominant-recessive inheritance, the dominant allele will overshadow the recessive allele. Choice D, 'Neither,' is incorrect as the phenotype will resemble the dominant allele.

3. Three students measured the mass of a product of combustion. They recorded measurements of 14 g, 16 g, and 17 g. If the known mass of the product is 30 g, how would you describe the students’ measurements?

Correct answer: B

Rationale: The students' measurements are precise because they are consistently close to each other. However, they are not accurate because all the measurements deviate from the known mass of the product (30 g). Accuracy refers to how close a measurement is to the true or accepted value, while precision refers to the level of agreement among repeated measurements. Since the students' measurements are consistent but do not align with the true value, they can be considered precise but not accurate. Choice A is incorrect because accuracy relates to the proximity of the measurements to the true value, which is not the case here. Choice C is incorrect because although the measurements are precise, they are not accurate. Choice D is incorrect because the measurements are precise as they show good agreement with each other, even though they are not accurate.

4. Why is DNA important for the metabolic activities of the cell?

Correct answer: D

Rationale: DNA is important for the metabolic activities of the cell because it controls the synthesis of enzymes. Enzymes are essential for catalyzing metabolic reactions in the cell. Choices A, B, and C are incorrect because DNA is not directly involved in cellular mitosis, cell wall stability, or glucose absorption.

5. What takes place in a lysosome?

Correct answer: D

Rationale: In a lysosome, food particles are digested through the action of enzymes. Lysosomes are membrane-bound organelles containing digestive enzymes that break down large molecules into smaller ones, allowing the cell to utilize the nutrients for energy and other processes. Choices A, B, and C are incorrect because ribosomes are not made in lysosomes, food is not produced in lysosomes, and lysosomes do not store water.

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