HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. Which component of the cell contributes to the protection, communication, and passage of substances into and out of the cell?
- A. Nucleus
- B. Cell membrane
- C. Endoplasmic reticulum
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the cell membrane. The cell membrane is responsible for protecting the cell, facilitating communication with the external environment, and regulating the passage of substances into and out of the cell. The nucleus (Choice A) is the control center of the cell and houses the genetic material but is not primarily involved in these functions. The endoplasmic reticulum (Choice C) is involved in protein synthesis and lipid metabolism, not primarily in protection or communication. The cytoplasm (Choice D) is the gel-like substance that fills the cell but does not specifically contribute to protection, communication, or substance passage.
3. What is the term for the breakdown of glycogen into glucose subunits?
- A. Hydrolysis
- B. Reduction
- C. Metabolism
- D. Transpiration
Correct answer: A
Rationale: Hydrolysis is the term used to describe the breakdown of large molecules into smaller units by adding water. In the case of glycogen being broken down into glucose subunits, this process involves the addition of water molecules to break the glycosidic bonds between glucose molecules, resulting in the release of individual glucose subunits. This process is crucial for providing cells with a source of energy when needed. Choice B, Reduction, refers to a chemical reaction involving a gain of electrons or a decrease in oxidation state, not the breakdown of glycogen into glucose subunits. Choice C, Metabolism, is a broad term encompassing all biochemical processes in an organism, including anabolism and catabolism, but does not specifically describe the breakdown of glycogen into glucose subunits. Choice D, Transpiration, is the process of water movement through a plant and is not related to the breakdown of glycogen into glucose subunits.
4. Which organelle is the site of energy production?
- A. Mitochondrion
- B. Vacuole
- C. Cell membrane
- D. Ribosome
Correct answer: A
Rationale: The correct answer is A: Mitochondrion. The mitochondrion is the site of energy production in a cell. It is often referred to as the powerhouse of the cell because it is where cellular respiration occurs, generating energy in the form of adenosine triphosphate (ATP) through processes like the citric acid cycle and oxidative phosphorylation. The other organelles listed play different roles in the cell - vacuoles store materials, the cell membrane regulates the movement of substances in and out of the cell, and ribosomes are involved in protein synthesis.
5. Which organelle is the site of photosynthesis in plant cells?
- A. Mitochondria
- B. Chloroplasts
- C. Ribosomes
- D. Endoplasmic Reticulum
Correct answer: B
Rationale: The correct answer is B: Chloroplasts. Chloroplasts are responsible for conducting photosynthesis in plant cells. They contain chlorophyll, a pigment that captures light energy and converts it into chemical energy through the process of photosynthesis. Mitochondria (choice A) are known as the powerhouse of the cell and are involved in cellular respiration, not photosynthesis. Ribosomes (choice C) are responsible for protein synthesis. The endoplasmic reticulum (choice D) is involved in protein and lipid synthesis and transport within the cell, not photosynthesis.
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