HESI A2
Biology HESI A2 2024
1. Imagine that two parents both carry the recessive gene for cystic fibrosis. Any homozygous recessive offspring will manifest the disease. What percentage of the offspring is predicted to be carriers but not manifest the disease?
- A. 0%
- B. 25%
- C. 50%
- D. 100%
Correct answer: B
Rationale: When both parents carry the recessive gene for cystic fibrosis (homozygous recessive), there is a 25% chance for each offspring to inherit two recessive alleles and, therefore, manifest the disease. There is also a 50% chance for each offspring to inherit one recessive allele and one dominant allele, making them carriers of the disease but not manifest it. Therefore, 25% of the offspring are predicted to be carriers but not manifest the disease. Choice A (0%) is incorrect because there is a portion of offspring that will be carriers. Choice C (50%) is incorrect as this percentage corresponds to carriers who will not manifest the disease. Choice D (100%) is incorrect as not all offspring will be carriers and not manifest the disease.
2. Where is the genetic information of a eukaryotic cell stored?
- A. Mitochondria
- B. Nucleus
- C. Golgi Apparatus
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is B: Nucleus. In eukaryotic cells, genetic information (DNA) is stored in the nucleus. This organelle acts as the control center of the cell, housing the DNA and regulating gene expression. Choices A, C, and D are incorrect because the genetic information is not stored in the mitochondria, Golgi Apparatus, or cytoplasm. The mitochondria are responsible for energy production, the Golgi Apparatus is involved in protein processing and packaging, and the cytoplasm is where various cellular activities take place, but none of these organelles store the genetic information.
3. Which of the following is always true about molecules?
- A. They cannot travel through all cell membranes
- B. They move from low concentration to high concentration without using energy
- C. They move from high concentration to low concentration without using energy
- D. They cannot move
Correct answer: C
Rationale: The statement that molecules move from high concentration to low concentration without using energy is always true due to the natural process of diffusion. This movement occurs to reach equilibrium and does not require any additional energy input directly from the molecule itself. Choice A is incorrect because not all molecules can travel through all cell membranes. Choice B is incorrect as molecules typically move from high concentration to low concentration in a process known as passive transport. Choice D is incorrect as molecules are in constant motion due to factors like temperature and kinetic energy.
4. Which of the following are components of the endocrine system?
- A. The pituitary gland
- B. The thyroid gland
- C. The adrenal glands
- D. All of the Above
Correct answer: D
Rationale: The endocrine system comprises a network of glands that produce and release hormones to regulate bodily functions. The pituitary gland, thyroid gland, and adrenal glands are essential components of this system. The pituitary gland secretes various hormones that control other glands and some body functions. The thyroid gland regulates metabolism, growth, and energy levels by producing thyroid hormones. The adrenal glands produce hormones involved in stress response, metabolism, and immune function. Therefore, all of the above glands are integral parts of the endocrine system, making choice D the correct answer.
5. Which is not one of the raw materials needed for cellular respiration?
- A. ADP
- B. Phosphate
- C. Water
- D. Glucose
Correct answer: C
Rationale: Water is not one of the raw materials needed for cellular respiration. The essential raw materials for cellular respiration include glucose (which is broken down to produce energy), oxygen, and ADP (adenosine diphosphate) and phosphate (which are necessary for the formation of ATP, the energy currency of cells). While water is crucial for many cellular processes and makes up a significant portion of cells, it is not directly involved as a raw material in the cellular respiration process.
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