during which phase of mitosis does the nuclear envelope disintegrate
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HESI A2

HESI A2 Biology Practice Test

1. During which phase of mitosis does the nuclear envelope disintegrate?

Correct answer: C

Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.

2. What type of transport moves substances across the cell membrane using energy?

Correct answer: B

Rationale: The correct answer is B: Active Transport. Active transport moves substances across the cell membrane by utilizing energy from the cell, typically in the form of ATP. This process allows the cell to move molecules against their concentration gradient, requiring energy expenditure. Choices A, C, and D are incorrect because passive transport does not require energy input, facilitated diffusion involves the assistance of proteins but does not directly use energy, and osmosis is the diffusion of water molecules specifically, not substances, across a selectively permeable membrane.

3. Huntington’s disease is carried on the dominant allele. In a situation where two heterozygous parents have the disease, what percentage of their offspring are predicted to be disease-free?

Correct answer: B

Rationale: In this scenario, both parents are heterozygous for Huntington's disease, meaning each carries one dominant allele (representing the disease) and one recessive allele (representing no disease). When they have offspring, there is a 25% chance that each child will inherit two recessive alleles, making them disease-free. The Punnett square for two heterozygous parents (Hh x Hh) yields a 25% probability of offspring being homozygous recessive (hh) and therefore disease-free. Choice A (0%) is incorrect because there is a possibility of disease-free offspring. Choice C (50%) is incorrect as it represents the likelihood of being a carrier. Choice D (100%) is incorrect as all offspring will not be disease-free in this scenario.

4. Which of the following cell types has no nucleus?

Correct answer: B

Rationale: The correct answer is B, red blood cell. In humans, red blood cells do not have a nucleus. This unique feature allows them to have more space to carry oxygen efficiently. Platelets (choice A), white blood cells (choice C), and phagocytes (choice D) all have nuclei. Platelets are cell fragments, while white blood cells and phagocytes are types of immune cells that contain a nucleus for DNA and cellular functions.

5. What kind of symbiosis exists between a pneumonia bacterium and a human?

Correct answer: B

Rationale: In the case of a pneumonia bacterium and a human, the relationship is best described as parasitism. The bacterium benefits by causing harm to the human host, while the human is negatively affected by the presence of the bacterium, leading to illness or infection. This is a classic example of a parasitic relationship where one organism benefits at the expense of the other. Mutualism (Choice A) is a type of symbiotic relationship where both organisms benefit from each other. Commensalism (Choice C) is a symbiotic relationship where one organism benefits, and the other is neither helped nor harmed. Competition (Choice D) refers to a relationship where both organisms are negatively affected by each other as they compete for resources.

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