HESI A2
HESI A2 Biology Practice Test
1. During which phase of mitosis does the nuclear envelope disintegrate?
- A. Prophase
- B. Prophase
- C. Prometaphase
- D. Metaphase
Correct answer: C
Rationale: During the prometaphase stage of mitosis, the nuclear envelope disintegrates. This allows the condensed chromosomes to move towards the center of the cell, preparing for their alignment along the metaphase plate. The breakdown of the nuclear envelope is a crucial step in mitosis to ensure the proper segregation of genetic material into daughter cells. Choices A, B, and D are incorrect as the nuclear envelope disintegration specifically occurs during the prometaphase stage, not in prophase or metaphase.
2. Why doesn't an antibiotic work for treating the flu?
- A. The antibiotic is for a different type of infection
- B. The antibiotic is not effective against viruses
- C. The antibiotic is not prescribed in a high enough dosage
- D. None of the above
Correct answer: B
Rationale: The correct answer is B. Antibiotics are used to treat bacterial infections, not viral infections like the flu. The flu is caused by a virus, and antibiotics are ineffective against viruses. Choice A is incorrect because it does not address the fact that antibiotics do not work on viruses. Choice C is incorrect as the issue is not related to the dosage amount, but rather the nature of the infection. Choice D is incorrect as there is a specific reason why antibiotics do not work for the flu.
3. Which of the following structures is not directly involved in translation?
- A. tRNA
- B. mRNA
- C. ribosome
- D. DNA
Correct answer: D
Rationale: The correct answer is 'D: DNA.' DNA is not directly involved in translation, which is the process of synthesizing proteins from mRNA. tRNA carries amino acids to the ribosome, mRNA provides the template for protein synthesis, and ribosomes are the cellular machinery where translation occurs. DNA's main role is in transcription, where it serves as the template for mRNA synthesis, not in translation.
4. Which of the following is a tertiary consumer?
- A. Owl
- B. Shrew
- C. Grasshopper
- D. Wheat
Correct answer: A
Rationale: The correct answer is A, Owl. Tertiary consumers are organisms that feed on secondary consumers, which, in turn, feed on primary consumers. Owls are considered tertiary consumers because they primarily feed on animals such as rodents, which are secondary consumers. Shrew (choice B) is a secondary consumer, feeding on insects and worms, placing it at a lower trophic level than the owl. Grasshopper (choice C) is a primary consumer, feeding on plants. Wheat (choice D) is not a consumer in the food chain but a plant.
5. Which of the following is true of the Krebs cycle?
- A. It is a redox reaction involving proteins produced during glycolysis
- B. It is a redox reaction involving sugars produced during glycolysis
- C. Protons are passed along a gradient to produce ATP
- D. It is also known as the glycolic acid cycle
Correct answer: B
Rationale: The Krebs cycle, also known as the citric acid cycle, involves a series of redox reactions that occur in the mitochondria. The cycle begins with the oxidation of acetyl CoA, which is derived from the breakdown of sugars produced during glycolysis. These sugars are broken down further in the Krebs cycle to produce ATP and reduce electron carriers such as NADH and FADH2. The cycle does not involve proteins produced during glycolysis. Protons are not passed along a gradient to produce ATP directly in the Krebs cycle; rather, they are used in the electron transport chain to generate ATP. The Krebs cycle is not known as the glycolic acid cycle; glycolysis is the metabolic pathway that produces pyruvate from glucose.
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