HESI A2
Biology HESI A2 Practice Exam
1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
2. Which structure controls the passage of substances into and out of the cell?
- A. Vacuole
- B. Cell Membrane
- C. Nuclear Membrane
- D. Cytoplasm
Correct answer: B
Rationale: The correct answer is the Cell Membrane. The cell membrane acts as a barrier that controls the passage of substances into and out of the cell. It is selectively permeable, allowing only certain molecules to pass through. Vacuole (Choice A), Nuclear Membrane (Choice C), and Cytoplasm (Choice D) do not primarily regulate the passage of substances in and out of the cell. Vacuoles are responsible for storage, the nuclear membrane surrounds the nucleus providing protection, and the cytoplasm is the fluid where organelles are suspended.
3. What are the three main events of the haploid cell cycle?
- A. DNA replication, mitosis, and cytokinesis
- B. DNA replication, meiosis, and cytokinesis
- C. DNA replication, cytokinesis, and degradation
- D. Mitosis, meiosis, and apoptosis
Correct answer: A
Rationale: In the haploid cell cycle, the three main events are DNA replication, where the cell's genetic material is duplicated; mitosis, which is the division of the nucleus to ensure each daughter cell receives a complete set of chromosomes; and cytokinesis, the division of the cell cytoplasm to separate the two daughter cells. Meiosis is not part of the haploid cell cycle as it occurs in diploid cells to produce haploid gametes. Apoptosis is a process of programmed cell death and is not a routine event in the cell cycle. Therefore, the correct answer is A. Choices B, C, and D are incorrect as meiosis and apoptosis are not part of the haploid cell cycle, and degradation is not a typical event in the cell cycle.
4. Which molecule is primarily responsible for storing energy in cells?
- A. Glucose
- B. ATP
- C. Fatty acids
- D. Starch
Correct answer: B
Rationale: ATP is the correct answer because it is the molecule responsible for storing and providing energy in cells. Glucose is a source of energy but not primarily for storage. Fatty acids are more involved in energy production through oxidation. Starch is a polysaccharide used for energy storage in plants.
5. What is the composition of the plasma membrane?
- A. Proteins
- B. Lipids
- C. Carbohydrates
- D. Nucleotides
Correct answer: B
Rationale: The plasma membrane is composed of lipids, proteins, and carbohydrates. While proteins are an essential component of the plasma membrane, it is not the only constituent. Carbohydrates and lipids also play crucial roles in the structure and function of the plasma membrane. Nucleotides are not part of the primary structural components of the plasma membrane, making this choice incorrect.
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