HESI A2
Biology HESI A2 Practice Exam
1. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
2. What is the process of cell division that results in two daughter cells with identical genetic material?
- A. Mitosis
- B. Meiosis
- C. Binary Fission
- D. Budding
Correct answer: A
Rationale: The correct answer is A, Mitosis. Mitosis is the process of cell division in which a cell divides and produces two daughter cells that are genetically identical to the parent cell. Choice B, Meiosis, is a type of cell division that produces gametes with half the number of chromosomes. Choice C, Binary Fission, is a form of asexual reproduction in single-celled organisms. Choice D, Budding, is a form of asexual reproduction where a new organism develops from an outgrowth or bud on the parent.
3. Why is the nucleus important in a cell?
- A. It stores the DNA
- B. It supports the cell
- C. It makes protein
- D. It makes energy out of food
Correct answer: A
Rationale: The nucleus is important in a cell because it stores the DNA, which contains the genetic information necessary for the cell's function and replication. This genetic material controls the cell's activities and characteristics. Choices B, C, and D are incorrect because supporting the cell, making proteins, and producing energy are functions typically associated with other cell organelles like the cytoskeleton, ribosomes, and mitochondria, respectively.
4. Which type of sugar is a disaccharide?
- A. Sucrose
- B. Fructose
- C. Glucose
- D. Galactose
Correct answer: A
Rationale: The correct answer is A, Sucrose. Sucrose is a disaccharide composed of one molecule of glucose and one molecule of fructose. When glucose and fructose combine, they form sucrose. Choice B, Fructose, is a monosaccharide, not a disaccharide. Choice C, Glucose, is also a monosaccharide, not a disaccharide. Choice D, Galactose, is another monosaccharide and not a disaccharide.
5. How should a researcher test the hypothesis that eating chocolate leads to acne in teenagers?
- A. Take 100 teenagers and feed each one a different amount of chocolate daily for 60 days; then test for acne.
- B. Take 100 teenagers and feed 50 two bars of chocolate daily for 60 days while the other 50 eat no chocolate; then test for acne.
- C. Take 1 teenager and feed him or her two bars of chocolate for 30 days and no chocolate for 30 days; then test for acne.
- D. Take 100 teenagers and feed them no chocolate for 30 days and two bars of chocolate apiece for 30 days; then test for acne.
Correct answer: B
Rationale: Option B is the correct approach to test the hypothesis that eating chocolate leads to acne in teenagers. This method involves having a control group (50 teenagers not consuming chocolate) and an experimental group (50 teenagers consuming two bars of chocolate daily), which allows for comparison. By having two distinct groups, researchers can assess the impact of chocolate consumption on acne development. Option A lacks a control group for comparison, making it harder to attribute any observed effects specifically to chocolate consumption. Option C only involves a single subject, which limits the generalizability of the results. Option D, where all teenagers experience both conditions, does not allow for a direct comparison between chocolate consumption and acne development, as all subjects are exposed to both conditions.
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