HESI A2
HESI A2 Biology 2024
1. Which is a byproduct of fermentation in muscle cells?
- A. Ethanol
- B. Pyruvic acid
- C. Lactic acid
- D. Oxygen
Correct answer: C
Rationale: Lactic acid is a byproduct of fermentation in muscle cells. During intense exercise or when oxygen is limited, muscle cells use anaerobic respiration to generate energy. This process breaks down glucose into lactic acid, which can cause muscle fatigue and soreness. Choice A, Ethanol, is not produced in muscle cells during fermentation. Choice B, Pyruvic acid, is an intermediate product in glucose metabolism but is not a byproduct of fermentation in muscle cells. Choice D, Oxygen, is not a byproduct of fermentation but a reactant in aerobic respiration.
2. Which organelle would you expect to be present in a cell responsible for detoxifying multiple molecules?
- A. rough ER
- B. smooth ER
- C. lysosome
- D. Golgi apparatus
Correct answer: B
Rationale: The smooth endoplasmic reticulum (ER) is the organelle responsible for detoxifying multiple molecules in a cell. It contains enzymes that help break down toxins and drugs, making it an essential organelle for detoxification processes. The rough ER, lysosome, and Golgi apparatus do not play direct roles in detoxification. The rough ER is mainly involved in protein synthesis and transport. Lysosomes are responsible for digestion and recycling within the cell. The Golgi apparatus is involved in modifying, sorting, and packaging proteins for secretion or for use within the cell.
3. What are the three main events of the haploid cell cycle?
- A. DNA replication, mitosis, and cytokinesis
- B. DNA replication, meiosis, and cytokinesis
- C. DNA replication, cytokinesis, and degradation
- D. Mitosis, meiosis, and apoptosis
Correct answer: A
Rationale: In the haploid cell cycle, the three main events are DNA replication, where the cell's genetic material is duplicated; mitosis, which is the division of the nucleus to ensure each daughter cell receives a complete set of chromosomes; and cytokinesis, the division of the cell cytoplasm to separate the two daughter cells. Meiosis is not part of the haploid cell cycle as it occurs in diploid cells to produce haploid gametes. Apoptosis is a process of programmed cell death and is not a routine event in the cell cycle. Therefore, the correct answer is A. Choices B, C, and D are incorrect as meiosis and apoptosis are not part of the haploid cell cycle, and degradation is not a typical event in the cell cycle.
4. Which of the following describes the situation where one allele takes a different form from another in a gene?
- A. phenotype
- B. heterozygous
- C. homolog
- D. homozygous
Correct answer: B
Rationale: Heterozygous is the term used to describe the genotype of an individual with two different alleles for a specific gene. In this case, one allele takes a different form from another, resulting in genetic diversity and variation in trait expression. The other choices are incorrect: 'phenotype' refers to the observable traits of an organism, 'homolog' typically refers to chromosomes that are similar in structure, and 'homozygous' describes the genotype where both alleles for a gene are the same.
5. Which organism reproduces via binary fission?
- A. Mushroom
- B. Blue whale
- C. Rainbow trout
- D. Salmonella
Correct answer: D
Rationale: The correct answer is D, Salmonella. Salmonella bacterium reproduces via binary fission, a form of asexual reproduction where the cell divides into two daughter cells with identical genetic material. This process is common among bacteria and single-celled organisms. Mushrooms reproduce through spores, blue whales and rainbow trout reproduce sexually, involving the fusion of male and female gametes. Therefore, choices A, B, and C are incorrect as they do not reproduce through binary fission.
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