HESI A2
HESI A2 Biology Practice Test
1. When the genotype consists of a dominant and a recessive allele, the phenotype will be like the _ allele.
- A. Dominant
- B. Recessive
- C. Both
- D. Neither
Correct answer: A
Rationale: When the genotype consists of a dominant and a recessive allele, the phenotype will be like the dominant allele. This is because dominant alleles typically mask the expression of recessive alleles. Therefore, the dominant allele will be expressed in the phenotype in most basic cases. The recessive allele will only be expressed phenotypically if the individual is homozygous recessive. Choice B, 'Recessive,' is incorrect because the phenotype will not be like the recessive allele in this case. Choice C, 'Both,' is incorrect because in simple dominant-recessive inheritance, the dominant allele will overshadow the recessive allele. Choice D, 'Neither,' is incorrect as the phenotype will resemble the dominant allele.
2. Which is a byproduct of fermentation in muscle cells?
- A. Ethanol
- B. Pyruvic acid
- C. Lactic acid
- D. Oxygen
Correct answer: C
Rationale: Lactic acid is a byproduct of fermentation in muscle cells. During intense exercise or when oxygen is limited, muscle cells use anaerobic respiration to generate energy. This process breaks down glucose into lactic acid, which can cause muscle fatigue and soreness. Choice A, Ethanol, is not produced in muscle cells during fermentation. Choice B, Pyruvic acid, is an intermediate product in glucose metabolism but is not a byproduct of fermentation in muscle cells. Choice D, Oxygen, is not a byproduct of fermentation but a reactant in aerobic respiration.
3. The phases of mitosis include:
- A. Prophase, interphase, metaphase, anaphase, and telophase
- B. Prophase, prophase, metaphase, anaphase, and cytokinesis
- C. Prophase, prometaphase, metaphase, anaphase, and telophase
- D. Prophase, interphase, prophase, anaphase, and telophase
Correct answer: C
Rationale: The correct phases of mitosis are prophase, prometaphase, metaphase, anaphase, and telophase. Prophase is the first phase where chromatin condenses into chromosomes, the nuclear envelope breaks down, and the mitotic spindle forms. Prometaphase follows prophase, involving the full disintegration of the nuclear envelope and the attachment of spindle fibers to the kinetochores of the chromosomes. Metaphase is where chromosomes align along the metaphase plate. Anaphase is the phase where sister chromatids separate and move towards opposite poles. Telophase marks the final stage of mitosis, involving the decondensation of chromosomes and the reformation of the nuclear envelope. Choice A is incorrect because it includes interphase, which is not a phase of mitosis. Choice B is incorrect as it repeats prophase, which is the initial phase. Choice D is incorrect because it includes interphase and repeats prophase.
4. Which of the following describes the situation where one allele takes a different form from another in a gene?
- A. phenotype
- B. heterozygous
- C. homolog
- D. homozygous
Correct answer: B
Rationale: Heterozygous is the term used to describe the genotype of an individual with two different alleles for a specific gene. In this case, one allele takes a different form from another, resulting in genetic diversity and variation in trait expression. The other choices are incorrect: 'phenotype' refers to the observable traits of an organism, 'homolog' typically refers to chromosomes that are similar in structure, and 'homozygous' describes the genotype where both alleles for a gene are the same.
5. Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. In an example of an unaffected father and a female carrier who have two daughters and two sons, which is the predicted outcome?
- A. Both daughters will carry the disease.
- B. Both sons will carry the disease.
- C. One daughter may have the disease.
- D. One son may have the disease.
Correct answer: C
Rationale: Duchenne muscular dystrophy is a recessive sex-linked trait carried on the X chromosome. Since the father is unaffected and does not carry the disease, he must have a normal X chromosome. The mother is a carrier, which means she has one normal X chromosome and one X chromosome with the disease allele. The daughters will inherit one X chromosome from each parent; one would be normal, and the other has a chance of carrying the disease allele. So, there is a 50% chance that one daughter may have the disease, as she could inherit the X chromosome with the disease allele. The sons will inherit the Y chromosome from the father and the X chromosome from the mother, so they will not be affected by the disease. Therefore, the predicted outcome is that one daughter may have the disease, while the sons will not carry the disease. This rules out choices A, B, and D.
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