what is the main idea of the passage about sickle cell anemia
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HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. What conclusion is suggested by this study from Germany?

Correct answer: D

Rationale: The study indicates that acupuncture is a reasonable treatment option for menstrual cramps, supported by the positive outcomes reported by participants in the study. The wording in option D directly aligns with the conclusion drawn from the findings, making it the correct answer.

3. The author suggests that persistent passivity and imperturbability may be a direct result of which of the following?

Correct answer: B

Rationale: The correct answer is B. The passage highlights that damage to the limbic system, specifically the amygdala, can lead to passivity and lack of aggression. This is supported by the statement that patients with trauma or damage to the amygdala exhibit a complete absence of aggression. Thus, a stroke causing severe tissue damage in the limbic system, including the amygdala, can result in persistent passivity and imperturbability. Choices A, C, and D are incorrect because they do not directly relate to damage in the limbic system, which is specifically mentioned in the passage as the cause of the described behaviors.

4. What is the meaning of the word 'enlist' as it is used in the second paragraph?

Correct answer: A

Rationale: In the context of the immune system, 'enlist' means to call into service. Immune cells recruit other cells to fight infection by producing chemicals that regulate their growth, behavior, and direct new recruits to trouble spots. This process is essential for the immune system's defense mechanism. The other choices are incorrect: 'write down' and 'put across' do not capture the action of mobilizing immune cells, and 'send away' is opposite in meaning to what is happening in the immune response.

5. Which of the following statements is an opinion?

Correct answer: A

Rationale: The statement that the connection between sleep and weight should be explored reflects a personal viewpoint rather than an objective fact. It indicates a belief that further research is warranted to understand this relationship better, making it an opinion and distinguishing it from the other factual statements presented in the passage.

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