what is the main idea of the passage about sickle cell anemia

HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

A. Bone pain is a symptom of sickle-cell anemia.
B. Sickle-cell anemia affects oxygen transport in the body.
C. Sickle-cell anemia is a genetically inherited disease.
D. Sickle-cell anemia is a painful, inherited disease.

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. What is the best title for the passage on bicycles?

A. Bicycles Are Better.
B. Cycle Your Way to Fitness.
C. A Ride through the History of Bicycles.
D. The Popularity of Bicycles.

Correct answer: C

Rationale: The correct answer is C: 'A Ride through the History of Bicycles.' This title best captures the passage's focus on the historical development and evolution of the bicycle from its invention to its modern form. Choice A, 'Bicycles Are Better,' is too general and doesn't encompass the historical aspect discussed in the passage. Choice B, 'Cycle Your Way to Fitness,' focuses solely on the fitness aspect of bicycles, ignoring the broader historical context. Choice D, 'The Popularity of Bicycles,' touches on one aspect but does not encompass the comprehensive historical journey presented in the passage.

3. Which of the following statements is an opinion related to Barefoot Running?

A. Running barefoot is natural and advantageous.
B. The cost of modern running shoes keeps increasing.
C. Concrete sidewalks are harder than dirt paths.
D. The arch of the foot gives a spring to the step.

Correct answer: A

Rationale: The statement that "running barefoot is natural and advantageous" reflects a subjective opinion, which cannot be definitively proven or measured objectively. The other statements (B, C, and D) provide factual observations or comparisons that can be validated through evidence, which distinguishes A as the only opinion-based statement.

4. A reader might infer from this passage that the organization ___________.

A. succeeded in eradicating malaria
B. has always been led by a medical doctor
C. no longer studies communicable diseases
D. changed its name to match its mission

Correct answer: D

Rationale: The passage never says whether or not the CDC succeeded in its original mission (choice A) or whether it continued to be led by doctors (choice B). Inferring either of those things would be a leap unsupported by the text. Choice C is countered by information in the final

5. What does the author suggest about the Earth's tilt in the passage on Daylight Savings Time?

A. The Earth's tilt has no effect on the seasons.
B. The Earth's tilt affects the amount of sunlight different areas receive.
C. The Earth's tilt is constant throughout the year.
D. The Earth's tilt changes dramatically during the seasons.

Correct answer: B

Rationale: The author suggests that the Earth's tilt affects the amount of sunlight different areas receive, influencing the seasons. The passage explains how the tilt of the Earth towards the sun results in different regions receiving varying amounts of sunlight, leading to the existence of seasons. This tilt causes regions near the equator to receive more sunlight consistently, while the Poles experience periods of constant darkness or sunlight, creating different seasons. Choices A, C, and D are incorrect because the passage clearly states that the Earth's tilt influences sunlight distribution and subsequently impacts the seasons.