what is the main idea of the passage about sickle cell anemia
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HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. The word watchdog as used in the second paragraph of the passage can best be defined as ___________.

Correct answer: B

Rationale: In this context, "watchdog" refers to a guard or overseer, specifically relating to Lifewings Partners’ mission of ensuring safety and preventing medical errors. The organization acts as a monitor in healthcare settings, which aligns with the definition of a watchdog, confirming that option B is correct.

3. Which statement from the selection presents a fact rather than an opinion?

Correct answer: B

Rationale: Statement B, 'Harsh voice qualities usually come from too much tension in the throat and jaw,' presents a fact rather than an opinion. This statement provides a clear and objective observation about the potential cause of harsh voice qualities, based on physical tension in specific areas of the body, which can be objectively measured and identified. Choice A is an opinion as it states 'One of the worst voice qualities is harshness' without providing a verifiable basis. Choice C lists subjective descriptors of an unpleasant voice without stating a definite cause. Choice D introduces a gender-based assertion about voice quality, making it an opinion rather than a factual observation.

4. A reader might infer from this passage that NASA ___________.

Correct answer: C

Rationale: The passage suggests that NASA will use the findings from the twin study to plan future extended space missions.

5. Which might be a good title for the passage about Barefoot Running?

Correct answer: D

Rationale: The title 'The Debate over Barefoot Running' captures the main discussion in the passage.

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