what is the main idea of the passage about sickle cell anemia

HESI A2

Reading Comprehension Practice Test HESI A2

1. What is the main idea of the passage about Sickle-Cell Anemia?

A. Bone pain is a symptom of sickle-cell anemia.
B. Sickle-cell anemia affects oxygen transport in the body.
C. Sickle-cell anemia is a genetically inherited disease.
D. Sickle-cell anemia is a painful, inherited disease.

Correct answer: D

Rationale: The correct answer is D. The passage focuses on describing sickle-cell anemia as a painful and inherited disease. It details how the abnormal sickle-shaped cells cause symptoms like bone pain, fever, and fatigue. While bone pain is mentioned as a symptom, it is not the main idea of the passage. Choice A is incorrect. Choice B, which mentions oxygen transport, is not the main idea but a general concept. Choice C, stating genetically inherited diseases affect thousands, is too broad and does not focus on the specifics of sickle-cell anemia. Therefore, D is the most precise choice.

2. Which of the following is not mentioned as a detail in the passage about High Fructose Corn Syrup?

A. HFCS and sugar share a biological structure.
B. HFCS is cheaper to use than sugar.
C. HFCS is now used to sweeten a variety of products.
D. HFCS contains more calories than aspartame.

Correct answer: D

Rationale: The correct answer is D because the passage does not mention that HFCS contains more calories than aspartame. While the passage discusses the concerns and implications of high fructose corn syrup (HFCS), it does not compare its caloric content to aspartame. Detail A is supported by the passage as both HFCS and sugar share a biological structure. Detail B is also mentioned in the passage, stating that HFCS is cheaper to use than sugar. Detail C is supported by the text, which mentions that HFCS is now used to sweeten a variety of products. However, detail D is never discussed in the passage, making it the correct answer.

3. In the passage the word embark means to:

A. Remove the covering from a tree
B. Speak harshly to others
C. Entertain the reader
D. Put or go on board a ship

Correct answer: D

Rationale: The word 'embark' typically means to board a ship or begin a journey. In this context, it means to start or set out on a new undertaking or venture, often including the act of boarding a ship. In the provided passage about the Golden Gate Bridge, it is mentioned that builders, architects, and workers embarked on the challenge of building a bridge across the Golden Gate Strait, which refers to them starting this new undertaking. Therefore, the correct definition of 'embark' is D. Put or go on board a ship. The other choices are incorrect: A. Removing the covering from a tree is unrelated to the context of the passage. B. Speaking harshly to others and C. Entertaining the reader are also irrelevant to the meaning of 'embark' in this context.

4. Which statement could be inferred from the passage?

A. The Georgia lab had conducted a previous study on the connection between exercise and energy.
B. Exercise regimes are not recommended for patients with serious health problems.
C. An increase in energy levels does not always correspond directly to a reduction in fatigue.
D. There were fewer than 10 participants in each group in the Georgia study.

Correct answer: A

Rationale: The correct answer is A. The passage mentions a previous study by the same team on the connection between exercise and energy, indicating that the lab had conducted such research before. Choice B is incorrect because the passage actually states that low-impact exercise can help reduce fatigue in patients with serious health conditions. Choice C is incorrect as the passage indicates that an increase in energy levels does correspond to a reduction in fatigue. Choice D is incorrect as the passage does not provide information on the exact number of participants in each group.

5. Which of the following statements is an opinion related to Barefoot Running?

A. Running barefoot is natural and advantageous.
B. The cost of modern running shoes keeps increasing.
C. Concrete sidewalks are harder than dirt paths.
D. The arch of the foot gives a spring to the step.

Correct answer: A

Rationale: The statement that "running barefoot is natural and advantageous" reflects a subjective opinion, which cannot be definitively proven or measured objectively. The other statements (B, C, and D) provide factual observations or comparisons that can be validated through evidence, which distinguishes A as the only opinion-based statement.