HESI A2
HESI A2 Biology Practice Test 2024
1. Where is the site of cellular respiration in eukaryotic cells?
- A. Nucleus
- B. Chloroplasts
- C. Mitochondria
- D. Ribosomes
Correct answer: C
Rationale: The correct answer is C: Mitochondria. Mitochondria are often referred to as the powerhouse of the cell because they are responsible for cellular respiration in eukaryotic cells. During cellular respiration, mitochondria generate energy in the form of ATP. Choices A, B, and D are incorrect. The nucleus is the organelle that houses the cell's genetic material, chloroplasts are responsible for photosynthesis in plant cells, and ribosomes are involved in protein synthesis, not cellular respiration.
2. Which of the following shows how information is transformed to make a protein?
- A. DNA-RNA-protein
- B. gene-chromosome-protein
- C. ATP-amino acid-protein
- D. RNA-DNA-protein
Correct answer: A
Rationale: The correct sequence of events for protein synthesis is that DNA is transcribed into RNA, which is then translated into a protein. This process is known as the central dogma of molecular biology. In this sequence, DNA serves as the template for RNA synthesis (transcription), and the RNA serves as the template for protein synthesis (translation). Choice B is incorrect as genes are segments of DNA that code for proteins, and chromosomes are structures that contain DNA. Choice C is incorrect as ATP is an energy molecule and amino acids are the building blocks of proteins, but they are not directly involved in the synthesis process. Choice D is incorrect because RNA is first transcribed from DNA and then used as a template to produce proteins.
3. What are plasma membranes mostly made of?
- A. Proteins
- B. Carbohydrates
- C. Lipids
- D. Nucleotides
Correct answer: C
Rationale: The correct answer is C: Lipids. Plasma membranes are primarily composed of lipids, specifically phospholipids, which form a lipid bilayer. While proteins are also an essential component of plasma membranes, they are not the primary constituent. Carbohydrates are present on the outer surface of the membrane but are not the main structural component. Nucleotides are the building blocks of nucleic acids like DNA and RNA and are not the main constituents of plasma membranes.
4. Which organelle is responsible for detoxifying harmful substances in the cell?
- A. Endoplasmic Reticulum
- B. Lysosomes
- C. Peroxisomes
- D. Golgi Apparatus
Correct answer: C
Rationale: The correct answer is C, Peroxisomes. Peroxisomes are responsible for detoxifying harmful substances in the cell by breaking down fatty acids and producing hydrogen peroxide. This process helps protect the cell from damage caused by toxic substances. Choice A, Endoplasmic Reticulum, is involved in protein and lipid synthesis, not detoxification. Choice B, Lysosomes, contain enzymes for digestion and waste removal, not primarily detoxification. Choice D, Golgi Apparatus, is responsible for modifying, sorting, and packaging proteins for secretion, not detoxification.
5. Which of the following are considered the most important molecules in biology?
- A. Carbohydrates, lipids, protein, and nucleic acids
- B. Carbohydrates, lipids, protein, and calcium
- C. Carbohydrates, lipids, protein, and sulfur
- D. Carbohydrates, lipids, protein, and iron
Correct answer: A
Rationale: The correct answer is A: Carbohydrates, lipids, protein, and nucleic acids are considered the most important molecules in biology. Carbohydrates are essential for providing energy, lipids for storing energy and forming cell membranes, proteins for various structural and functional roles, and nucleic acids (DNA and RNA) for storing genetic information. Choices B, C, and D are incorrect because while carbohydrates, lipids, and proteins are crucial biomolecules, calcium, sulfur, and iron are not considered among the most important molecules in biology.
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