HESI A2
HESI A2 Biology 2024
1. In contrast with triglycerides, phospholipids are lacking one of which of the following components?
- A. Monosaccharide
- B. Glycerol
- C. Phosphates
- D. Fatty acid
Correct answer: B
Rationale: Phospholipids are structurally similar to triglycerides but lack one of the fatty acid chains that triglycerides possess. Triglycerides consist of three fatty acid chains attached to a glycerol molecule, while phospholipids have two fatty acid chains and a phosphate group attached to a glycerol backbone. Therefore, phospholipids are lacking the third fatty acid chain found in triglycerides. Choice A (Monosaccharide) is incorrect because neither triglycerides nor phospholipids contain monosaccharides in their structure. Choice C (Phosphates) is incorrect because phospholipids actually contain phosphates, unlike triglycerides. Choice D (Fatty acid) is incorrect as both triglycerides and phospholipids contain fatty acids, but the number of fatty acid chains differs between the two.
2. 72 chromosomes undergo meiosis. How many chromosomes will be in each gamete?
- A. 18
- B. 36
- C. 72
- D. 144
Correct answer: A
Rationale: During meiosis, the number of chromosomes is halved in each gamete. Since 72 chromosomes undergo meiosis, each gamete will contain half of that number, which is 36 chromosomes. Therefore, the correct answer is 18 chromosomes in each gamete. Choice B (36 chromosomes) is incorrect because it represents the total number of chromosomes that undergo meiosis, not the number in each gamete. Choice C (72 chromosomes) is incorrect as it represents the initial number of chromosomes, not the number in each gamete after meiosis. Choice D (144 chromosomes) is incorrect as it doubles the initial number of chromosomes, which is not the outcome of meiosis.
3. What are the three main events of the haploid cell cycle?
- A. DNA replication, mitosis, and cytokinesis
- B. DNA replication, meiosis, and cytokinesis
- C. DNA replication, cytokinesis, and degradation
- D. Mitosis, meiosis, and apoptosis
Correct answer: A
Rationale: In the haploid cell cycle, the three main events are DNA replication, where the cell's genetic material is duplicated; mitosis, which is the division of the nucleus to ensure each daughter cell receives a complete set of chromosomes; and cytokinesis, the division of the cell cytoplasm to separate the two daughter cells. Meiosis is not part of the haploid cell cycle as it occurs in diploid cells to produce haploid gametes. Apoptosis is a process of programmed cell death and is not a routine event in the cell cycle. Therefore, the correct answer is A. Choices B, C, and D are incorrect as meiosis and apoptosis are not part of the haploid cell cycle, and degradation is not a typical event in the cell cycle.
4. Patient A, who weighs 68 kilograms, steps onto a scale 20 times. The scale consistently weighs Patient A as 75 kilograms. What is true of the measurement?
- A. It is valid, but not reliable.
- B. It is reliable, but not valid.
- C. It is both valid and reliable.
- D. It is neither reliable nor valid.
Correct answer: B
Rationale: The correct answer is B: 'It is reliable, but not valid.' The measurement is reliable because it consistently provides the same result (75 kg). However, it is not valid because it does not accurately reflect the true weight of Patient A (68 kg). Choice A is incorrect because if the scale consistently shows the same weight (75 kg), it is reliable. Choice C is incorrect because although the scale is consistent, the measurement does not reflect the true weight, making it not valid. Choice D is incorrect as the measurement is reliable but lacks validity.
5. In an example of a male with hemophilia and a female carrier, what ratio of the offspring is predicted to have the disease?
- A. 0 female : 2 males
- B. 1 female : 0 males
- C. 1 female : 2 males
- D. 2 females : 1 male
Correct answer: C
Rationale: In this scenario, the male offspring will inherit the hemophilia trait from their mother due to the sex-linked inheritance pattern. The female offspring will inherit one X chromosome from their mother, becoming carriers of hemophilia. Therefore, the predicted ratio of offspring with the disease would be 1 female as a carrier and 2 males with hemophilia. Choice A is incorrect because there would be male offspring with the disease. Choice B is incorrect as there would be male offspring with hemophilia. Choice D is incorrect as it does not reflect the inheritance pattern of hemophilia.
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