HESI LPN
HESI Maternal Newborn
1. What causes Down's syndrome?
- A. Alcohol abuse by the mother at the time of conception.
- B. Sex-linked chromosomal abnormalities.
- C. An extra chromosome on the 21st pair.
- D. Drug abuse by the mother during pregnancy.
Correct answer: C
Rationale: Down's syndrome, also known as trisomy 21, is caused by the presence of an extra chromosome on the 21st pair. Choice A is incorrect as alcohol abuse is not the cause of Down's syndrome. Choice B is incorrect because Down's syndrome is not related to sex-linked chromosomal abnormalities. Choice D is also incorrect as drug abuse by the mother during pregnancy is not the cause of Down's syndrome.
2. A client at 27 weeks of gestation with preeclampsia is being assessed by a nurse. Which of the following findings should the nurse report to the provider?
- A. Urine protein concentration of 200 mg/24 hr.
- B. Creatinine level of 0.8 mg/dL
- C. Hemoglobin level of 14.8 g/dL
- D. Platelet count of 60,000/mm3
Correct answer: D
Rationale: A platelet count of 60,000/mm3 is significantly low and can indicate HELLP syndrome, a severe complication of preeclampsia that involves hemolysis, elevated liver enzymes, and low platelet count. HELLP syndrome requires prompt medical intervention to prevent serious maternal and fetal complications. The other findings listed are within normal limits or not directly related to the severe condition associated with HELLP syndrome.
3. After meiosis, each new cell nucleus contains _____ chromosomes.
- A. 46
- B. 35
- C. 23
- D. 12
Correct answer: C
Rationale: After meiosis, each resulting cell contains 23 chromosomes. Meiosis is a process that involves two sequential divisions resulting in four daughter cells, each with half the number of chromosomes as the parent cell. In humans, the parent cell has 46 chromosomes (diploid), and after meiosis, the resulting cells (sperm or ova) have 23 chromosomes (haploid). Choice A (46 chromosomes) is incorrect because this is the number of chromosomes in a human diploid cell before meiosis. Choices B (35 chromosomes) and D (12 chromosomes) are incorrect as they do not represent the correct number of chromosomes after meiosis in human cells.
4. Are sperm much larger than ova?
- A. TRUE
- B. FALSE
- C. Sometimes
- D. Always
Correct answer: B
Rationale: The correct answer is B: FALSE. Ova, also known as eggs, are actually the largest cells in the human body, while sperm are significantly smaller. This size difference is due to the different functions of the two gametes. Sperm are specialized for motility to reach and fertilize the egg, while ova contain nutrients and cellular machinery needed for fertilization and early embryonic development. Choices A, C, and D are incorrect because sperm are not larger than ova; they are much smaller in size.
5. Which of the following conditions is considered a multifactorial problem?
- A. Cystic fibrosis
- B. Down syndrome
- C. Diabetes mellitus
- D. XYY syndrome
Correct answer: C
Rationale: The correct answer is 'Diabetes mellitus' because it is a multifactorial disease, influenced by both genetic predisposition and environmental factors. Cystic fibrosis (choice A) is primarily a genetic disorder caused by mutations in the CFTR gene. Down syndrome (choice B) is due to an extra copy of chromosome 21. XYY syndrome (choice D) is a genetic condition where males have an extra Y chromosome. These conditions are not considered multifactorial as their origins are primarily genetic.
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