downs syndrome is caused by

HESI LPN

HESI Maternal Newborn

1. What causes Down's syndrome?

A. Alcohol abuse by the mother at the time of conception.
B. Sex-linked chromosomal abnormalities.
C. An extra chromosome on the 21st pair.
D. Drug abuse by the mother during pregnancy.

Correct answer: C

Rationale: Down's syndrome, also known as trisomy 21, is caused by the presence of an extra chromosome on the 21st pair. Choice A is incorrect as alcohol abuse is not the cause of Down's syndrome. Choice B is incorrect because Down's syndrome is not related to sex-linked chromosomal abnormalities. Choice D is also incorrect as drug abuse by the mother during pregnancy is not the cause of Down's syndrome.

2. Which of the following pairs share 100% of their genes?

A. Biovular twins
B. Fraternal twins
C. Dizygotic (DZ) twins
D. Monozygotic (MZ) twins

Correct answer: D

Rationale: The correct answer is Monozygotic (MZ) twins. Monozygotic twins, also known as identical twins, share 100% of their genes because they originate from the same fertilized egg that splits into two. Fraternal twins (choice B), also known as dizygotic (DZ) twins (choice C), result from two separate fertilized eggs and share approximately 50% of their genes. Biovular twins (choice A) is not a term used in genetics and does not describe a type of twinning.

3. What is the primary role of meiosis in the production of sperm and ova?

A. To reduce the chromosome number by half
B. To increase the chromosome number
C. To create identical copies of chromosomes
D. To repair damaged chromosomes

Correct answer: A

Rationale: The correct answer is A. Meiosis is a type of cell division that reduces the chromosome number by half, resulting in the formation of sperm and ova. Choice B is incorrect because meiosis does not increase the chromosome number. Choice C is incorrect because meiosis creates genetically diverse gametes, not identical copies of chromosomes. Choice D is incorrect because meiosis does not primarily function to repair damaged chromosomes.

4. What information should the nurse include when teaching a client at 41 weeks of gestation about a non-stress test?

A. This test will confirm fetal lung maturity.
B. This test will determine the adequacy of placental perfusion.
C. This test will detect fetal infection.
D. This test will predict maternal readiness for labor.

Correct answer: B

Rationale: The correct answer is B: 'This test will determine the adequacy of placental perfusion.' The non-stress test is used to assess fetal well-being by monitoring the fetal heart rate in response to its own movements. It helps determine if the fetus is receiving enough oxygen and nutrients through placental perfusion. Choice A is incorrect because confirming fetal lung maturity is typically determined through tests like amniocentesis, not the non-stress test. Choice C is incorrect because detecting fetal infection is not the primary purpose of a non-stress test. Choice D is incorrect because predicting maternal readiness for labor is not the purpose of the non-stress test; it focuses on fetal well-being.

5. Which of the following is a fatal genetic neurologic disorder whose onset is in middle age?

A. Tay-Sachs disease
B. Duchenne muscular dystrophy
C. Hemophilia
D. Huntington’s disease

Correct answer: D

Rationale: Huntington's disease is a fatal genetic neurologic disorder characterized by progressive nerve cell degeneration in the brain. It typically manifests in middle age with symptoms such as involuntary movements, cognitive decline, and psychiatric disturbances. Tay-Sachs disease (Choice A) is a genetic disorder that primarily affects the nervous system in early childhood, not middle age. Duchenne muscular dystrophy (Choice B) is a genetic disorder that primarily affects muscle function and usually presents in early childhood. Hemophilia (Choice C) is a genetic disorder related to blood clotting, and its onset is not typically in middle age.