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HESI Maternal Newborn
1. What causes Down's syndrome?
- A. Alcohol abuse by the mother at the time of conception.
- B. Sex-linked chromosomal abnormalities.
- C. An extra chromosome on the 21st pair.
- D. Drug abuse by the mother during pregnancy.
Correct answer: C
Rationale: Down's syndrome, also known as trisomy 21, is caused by the presence of an extra chromosome on the 21st pair. Choice A is incorrect as alcohol abuse is not the cause of Down's syndrome. Choice B is incorrect because Down's syndrome is not related to sex-linked chromosomal abnormalities. Choice D is also incorrect as drug abuse by the mother during pregnancy is not the cause of Down's syndrome.
2. When assessing a woman in the first stage of labor, which clinical finding will alert the nurse that uterine contractions are effective?
- A. Dilation of the cervix.
- B. Descent of the fetus to –2 station.
- C. Rupture of the amniotic membranes.
- D. Increase in bloody show.
Correct answer: A
Rationale: During the first stage of labor, effective uterine contractions lead to cervical dilation. Dilation of the cervix is a key indicator that uterine contractions are progressing labor. Descent of the fetus to -2 station (Choice B) is related to the fetal position in the pelvis and not a direct indicator of uterine contraction effectiveness. Rupture of the amniotic membranes (Choice C) signifies the rupture of the fluid-filled sac surrounding the fetus and does not directly reflect uterine contraction effectiveness. An increase in bloody show (Choice D) can be a sign of impending labor, but it is not a direct indicator of uterine contraction effectiveness.
3. According to a study in 2013 by van Gameren-Oosterom, individuals with Down syndrome:
- A. are unlikely to die from cardiovascular problems by middle age.
- B. have no specific characteristic features.
- C. show deficits in cognitive development.
- D. are likely to have only 46 chromosomes.
Correct answer: C
Rationale: The correct answer is C. According to a study in 2013 by van Gameren-Oosterom, individuals with Down syndrome often exhibit deficits in cognitive development. This is a common characteristic of Down syndrome, along with other health challenges. Choice A is incorrect because individuals with Down syndrome are at a higher risk of cardiovascular problems, contrary to being unlikely to die from them. Choice B is incorrect as Down syndrome is associated with specific characteristic features such as distinctive facial characteristics, making the statement that they have no specific features incorrect. Choice D is incorrect as individuals with Down syndrome have an extra copy of chromosome 21, resulting in a total of 47 chromosomes, not 46.
4. In the structure of deoxyribonucleic acid (DNA), which of the following bases combines with thymine?
- A. Cytosine
- B. Adenine
- C. Rhodamine
- D. Serine
Correct answer: B
Rationale: The correct answer is B: Adenine. In the structure of DNA, adenine pairs with thymine through hydrogen bonding, forming one of the complementary base pairs that make up the double helix structure of DNA. Cytosine pairs with guanine, not thymine. Rhodamine and serine are not DNA bases and do not participate in DNA base pairing. Therefore, choices A, C, and D are incorrect.
5. Females with Turner syndrome:
- A. possess more thymine than cytosine.
- B. are taller than average.
- C. produce little estrogen.
- D. are more likely to give birth to twins.
Correct answer: C
Rationale: Turner syndrome is a chromosomal disorder in females characterized by short stature and underdeveloped ovaries, resulting in low estrogen production. This leads to symptoms such as delayed puberty and infertility. Choice A is incorrect because the chromosomal abnormality in Turner syndrome does not affect the thymine-cytosine ratio. Choice B is incorrect as females with Turner syndrome are typically shorter than average. Choice D is incorrect as Turner syndrome does not increase the likelihood of giving birth to twins.
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